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n views 84773 comments 0 do netflix spotify and facebook know me as well as they think websites try to suggest everything from your next best friend to your next best shirt but are these recommendations a help or a hindrance computer science source theguardian views 90092 comments 0 great barrier reef species more at risk from climate change says study tropical species with smaller geographical ranges are more likely to die out in a warming climate than those that can adapt by invading new regions marine biology source theguardian views 90670 comments 0 yellow gets greener in summer remember winter when everything was cold and grey right now when all around is lush and green the contrast couldn t be greater but is everything really as it seems new research shows that we see things differently in winter compared with summer health source theguardian views 84408 comments 0 the bacteria that turn amoebas into farmers most people think of bacteria as germs signs of filth or unwanted bringers of disease slowly that view microbiology source national geographic views 84786 comments 0 octopuses seen throwing things may be using shells as weapons the gloomy octopuses crowded at jervis bay australia appear to spit and throw debris such as shell at each other in what could be an intentional use of weapons animal behavior source new scientist views 85124 comments 0 hormones boost placebo effect by making you want to cooperate therapies based on hormones that make us more trusting enhance our natural placebo effect a finding that could alter the way clinical trials are conducted neuroscience source new scientist views 85126 comments 0 app gives smartphone snaps more than 5 million different filters a new app called infltr taps into a smartphone s graphics processor to generate filters on the fly allowing for the perfect shot in one step technology source new scientist views 90543 comments 0 stephen hawking says he has a way to escape from a black hole researchers have long struggled to resolve what happens to information when it falls inside a black hole but the famous physicist says he has a solution physics source new scientist views 84923 comments 0 these newborn pandas face 4 big threats to survival the blind hairless babies born recently at washington d c s national zoo are completely dependent on their mothers who can sometimes accidentally crush them animal behavior source national geographic news views 84735 comments 0 why dung beetles watch the sky while rolling poop balls the poop hoarding insects have an amazingly advanced internal gps that allows them to navigate by day or night animal behavior source national geographic news views 84925 comments 0 why windows 95 was a game changer for computer users windows 95 the operating system update that changed the way millions of people interacted with their computers was released 20 years ago today computer science source abc news views 90065 comments 0 particles from the edge of space shine a light on fukushima researchers have been using muons to take a peek inside the nuclear reactors in japan that melted down in 2011 the results could aid the continuing cleanup operations physics source npr views 85416 comments 0 when whole genome sequencing doesn t give us the whole genome author brian krueger phd views 24040 comments 0 image courtesy of shutterstock if you re an avid follower of popular science in today s news media you might have noticed a recurring theme genomics is everywhere on an almost weekly basis the new york times the new yorker forbes and a myriad of other outlets are publishing stories with overly optimistic ledes about doctors and gene sequencers being replaced by apps and iphone accessories you would be forgiven if you thought genomics was solved and we re 5 years out from creating a star trek inspired tricorder that near instantly sequences your genome and tells you without equivocation what malady is afflicting you and how exactly to overcome said disorder the fact of the matter is that we re not there yet not by a long shot more 5 predictions for agbt15 author brian krueger phd views 13004 comments 0 the advances in genome biotechnology conference starts tomorrow in marco island fl twitter and the blogs have been a flurry of speculation about what the major vendors will present at this years meeting in previous years we ve seen the introduction of new disruptive technologies such as the ion torrent platform the oxford nanopore minion and the pacbio rs like many i have mixed emotions about this conference it s more ces than science given the history of the major announcements and where those products are now 3 and 5 years out it s hard to get excited about a show stopper while technically impressive the minion is still mired in problems that were glossed over in the fanfare of the original announcement and pacbio is finally starting to deliver on the promises it made eons ago i should also mention my disappointment with ion torrent here this is yet another company that made a major announcement at agbt and failed spectacularly keith robison thinks they still have a sho more have we entered the era of the 1 year sequencer release cycle updated author brian krueger phd views 23799 comments 0 yesterday marked the kickoff of the jp morgan healthcare conference in san francisco following last years lead illumina once again used this platform as an opportunity to announce the release of a number of new products including 4 new sequencing systems ahead of the more scientifically focused advances in genome biotechnology conference in february at this same time in 2014 illumina presented the hiseq x ten sequencing system which is a system for population scale genomics composed of ten hiseq x sequencers illumina touted this system s reduced reagent price increased speed and expanded capacity it has now taken much of the technology from this hiseq x system and put it into two new lower tier models the hiseq 3000 and hiseq 4000 more illumina s 1000 genome author brian krueger phd views 12739 comments 0 illumina the world leader in short read dna sequencing made a series of very big announcements yesterday at the jpmorgan healthcare conference these developments have many sequencing labs around the world excited and worried all at the same time the excitement comes from the fact that it appears on the surface that illumina has broken the 1000 genome barrier the worry comes from the realization that only a few of us can afford it more ch ch ch changes author brian krueger phd views 16886 comments 0 it s been a long run and we have a strong readership of the press releases but sadly i no longer have the time or the interest to continue posting press releases on the site my additional work commitments here at duke have really limited the amount of time i can devote to this and grabbing the press releases every night morning for an hour or two just became tedious i d like to spend my free time doing more creative things so hopefully i ll give my neglected blog some attention over the next few months to those who have been loyal followers of the press releases thanks for your devotion and continued support it does pain me to stop posting the press releases knowing they are served to nearly a million visitors a month but i just do not have the time or desire to continue these activities i will however continue to post link to mainstream news stories and blog posts i find interesting so keep an eye on twitter and the right hand column here on the blogs i ll be adding a from the web section shortly the blogs will still be here for anyone that would like to use them as an outlet just send me an email or contact me on twitter more a coming of age for pacbio and long read sequencing agbt13 author brian krueger phd views 30510 comments 9 last by michael schatz on feb 26 2013 12 13am aside from the dubstep pumping out of the roche and agilent booths the volume of agbt has been somewhat muted there was no grand offering of new hardware or over the top promises of sequencing genomes on what now appear to be vaporware usb thumb drives this is my first in person experience of agbt so as a virgin it seems for the most part to be rooted in the science despite the ridiculous parties and showgirl casino nights the atmosphere here is unlike any other science conference i ve attended it s like the bastard child of a gordon conference and a las vegas porn convention i really hope that the deep pockets of sequencing centers are more influenced by the science than the free dinner parties and alcohol but i have pretty low confidence in humanity regardless i think everyone in attendance today was overwhelmed by a stunning talk from pacbio and the dramatic advancements of their long read technology the pacbio talk came on the heels of what felt like a warm up opening act from jeremy schmutz of the hudson alpha institute schmutz has been working with a start up that was recently acquired by illumina called more next generation sequencing rapidly moves from the bench to the bedside agbt13 author brian krueger phd views 13241 comments 0 as the second day of agbt kicked off it became quite clear that this meeting would be dominated by medical genomics there were a few talks sprinkled in about gut or sewer microbiomes but the vast majority of the talks the last two days have been on clinical genomic sequencing this is fine by me since it s exactly what we do in the genomic analysis facility in duke s center for human genome variation it s really nice to see how other centers are approaching these problems unfortunately this is one of the few opportunities we have to peek into each other s operations yesterday s first talk was by russ altman of stanford university russ has been a leader in the field of pharmacogenomics and he presented his work on developing the pharmacogenomics knowledgebase pharmgkb pharmgkb org he led by saying don t ever give a talk about a website and in his case it was true because wifi in the conference room was down for the majority of his talk he urged the crowd to follow along on the website but only those of us with a cell connection could join him russ pointed out the major drawbacks of using gwas and snp chips for obtaining information about pharmacoenomic associations and joined pretty much everyone else in saying that the standard t more agbt day one talks and observations wes wgs kissing snails poo bacteria sequencing author brian krueger phd views 12951 comments 2 last by brian krueger phd on feb 21 2013 11 42pm today i dusted off my luggage and headed down to the annual advances in genome biology and technology meeting in marco island fl historically this meeting has been the detroit auto show of genomics where companies and labs release their beautiful shiny new products and methodologies in past years attendees were showered with fireworks displays and epic swag bags the tone this year is palpably more mutated one only has to point to the display banners located on the agbt presenter stage for evidence of this banners for bronze and silver sponsors appear to hang waiting for accompaniment by gold and platinum brethren there s even space allocated for them despite the tightened biotech purse strings the event appears from the outset to be extremely well organized there could be a few more power outlets for those of us carrying a small fortune in lithium powered devices but i guess i ll manage and of course there s no live streaming or any form of web enabled anything but i can gripe about that in a long winded and whiny post next week the evening opened with a brief introduction with a description of some new meeting changes this is the biggest agbt yet with over 800 attendees a new abstract selection committee was created more got fetal dna on the brain author brian krueger phd views 9846 comments 3 last by brian krueger phd on sep 28 2012 5 02pm one of the big stories that blew up on the internet the other day was the publication of some results that reportedly show that females who have birthed males have male dna in their brain that s pretty cool stuff this isn t uncommon it s called microchimerism or the deposition of cells or dna from the fetus to the mother or vice versa it has been shown in both mice and humans that the blood of the mother contains snippets of fetal dna and even whole cells these have even been used to completely sequence a fetal genome using only the blood of the mother the finding that these dna fragments or cells can deposit themselves in the human brain is novel and potentially cool from a brain regulation standpoint maybe baby boy brain cells change the mother s brain however a quick read of the abstract of the paper yesterday immediately raised a few red flags in my own brain absolutely full of male cells by the way the discovery was made using quantitative real time pcr and only quantitative real time pcr on a highly repetitive male gene on the y chromosome most people who aren t scientists don t more memes about junk dna miss the mark on paradigm shifting science author brian krueger phd views 10797 comments 2 last by brian krueger phd on sep 08 2012 12 05pm in 1990 the scientific community embarked on a landmark experiment to completely sequence the human genome at the time it was assumed that knowing the exact sequence of the human genome would provide scientists all of the information they ever wanted to know about genomics and how dna contributes to human disease at least this is how the project was presented to the public however every genome scientist knew that obtaining the sequence of the human genome was a lot like getting a cake recipe that listed all of the ingredients but didn t explain at all how much of each ingredient to use how to mix the ingredients together or how long to bake that mixture to create a delicious cake compound that with the fact that the list contains over 35 000 ingredients and you can quickly understand why the sequence alone wasn t very informative we spent over 3 billion dollars to obtain this sequence and since the final publication of the sequence in 2003 the media has questioned its usefulness apparently because cancer wasn t cured in 10 years the human genome project is largely seen by the media as a colossal waste of money however obtaining this sequence has been invaluable in speeding up research and has significantly contributed to our understanding of how som more so you ve dropped a cryovial or lost a sample box in your liquid nitrogen container now what author brian krueger phd views 34587 comments 6 last by mike gruidl on feb 22 2013 1 22pm it s bound to happen in every lab someone is going to get distracted and for whatever reason a box full of tubes or tubes themselves are going to accidentally get dropped in the lab s liquid nitrogen container a lot of people might say screw it and leave those samples on the bottom of the tank this might be a good solution for some samples but w...
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