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eric lesage florian fink michel romey georges lazdunski michel may 1999 inhalational anesthetics activate two pore domain background k channels nature neuroscience 2 5 422 426 doi 10 1038 8084 pmid 10321245 s2cid 23092576 von hintzenstern u schwarz w 1 february 1996 frühe erlanger beiträge zur theorie und praxis der ather und chloroformnnarkose early contributions from erlangen to the theory and practice of ether and chloroform anesthesia 1 heyfelder s clinical trial with ether and chloroform der anaesthesist in german 45 2 131 139 doi 10 1007 s001010050247 pmid 8720885 an experience with the new anæsthetic chloroform ether and absolute alcohol the independent practitioner 4 2 97 100 february 1883 pmc 10072673 pmid 37826124 shah shrey p bause george s september 2020 from ace to aceno how america s munson added harley s british mixture to nitrous oxide journal of anesthesia history 6 3 168 169 doi 10 1016 j janh 2020 07 006 pmid 32921491 knight paul r iii bacon douglas r 2002 an 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chloroform chloroform administration a short film of anaesthetic chloroform application filmed in the 1930s concise international chemical assessment document 58 iarc summaries evaluations vol 1 1972 vol 20 1979 suppl 7 1987 vol 73 1999 international chemical safety card 0027 niosh pocket guide to chemical hazards 0127 national institute for occupational safety and health niosh nist standard reference database v t e halomethanes by substitution pattern unsubstituted ch 4 monosubstituted ch 3 f ch 3 cl ch 3 br ch 3 i ch 3 at disubstituted x x ch 2 f 2 ch 2 cl 2 ch 2 br 2 ch 2 i 2 x y ch 2 clf ch 2 brf ch 2 fi ch 2 brcl ch 2 cli ch 2 bri trisubstituted x x x chf 3 chcl 3 chbr 3 chi 3 x x y chclf 2 chbrf 2 chf 2 i chcl 2 f chbr 2 f chfi 2 chbrcl 2 chcl 2 i chbr 2 cl chcli 2 chbr 2 i chbri 2 x y z chbrclf chclfi chbrfi chbrcli tetrasubstituted x x x x cf 4 ccl 4 cbr 4 ci 4 x x x y cfi 3 cclf 3 cbrf 3 cf 3 i ccl 3 f cbr 3 f cbrcl 3 ccl 3 i cbr 3 cl ccli 3 cbr 3 i cbri 3 x x y y ccl 2 f 2 cbr 2 f 2 cf 2 i 2 cbr 2 cl 2 ccl 2 i 2 cbr 2 i 2 x x y z cbrclf 2 cclf 2 i cbrf 2 i cbrcl 2 f ccl 2 fi cbr 2 clf cclfi 2 cbr 2 fi cbrfi 2 cbrcl 2 i cbr 2 cli cbrcli 2 x y z w cbrclfi special types chiral chbrclf chclfi chbrfi chbrcli cbrclfi isotopologues c 2 h 2 cl 2 cd 2 cl 2 c 2 hcl 3 cdcl 3 c 2 h 3 i cd 3 i v t e general anesthetics n01a inhalational chloroform cyclopropane desflurane diethyl ether enflurane ethylene fluroxene halothane isoflurane methoxyflurane methoxypropane nitrous oxide sevoflurane trichloroethylene thiomethoxyflurane vinyl ether xenon injection phenols cipepofol ciprofol fospropofol propofol barbiturates amobarbital hexobarbital methohexital narcobarbital thiamylal thiopental thiotetrabarbital benzodiazepines midazolam diazepam lorazepam remimazolam opioids morphine oxycodone anileridine embutramide fentanyl alfentanil phenoperidine remifentanil sufentanil arylcyclohexylamines esketamine ketamine phencyclidine tiletamine neuroactive steroids alfadolone alfaxalone hydroxydione others etomidate propoxate metomidate propanidid who em withdrawn from market clinical trials phase iii never to phase iii pharmacodynamics v t e gaba a receptor positive modulators alcohols brometone butanol chloralodol chlorobutanol cloretone ethanol alcohol alcoholic drink ethchlorvynol isobutanol isopropanol menthol methanol methylpentynol pentanol petrichloral propanol tert butanol 2m2p tert pentanol 2m2b tribromoethanol trichloroethanol triclofos trifluoroethanol barbiturates dmbb allobarbital alphenal amobarbital aprobarbital barbexaclone barbital benzobarbital benzylbutylbarbiturate brallobarbital brophebarbital butabarbital secbutabarbital butalbital buthalital butobarbital butallylonal carbubarb crotylbarbital cyclobarbital cyclopentobarbital difebarbamate enallylpropymal ethallobarbital eterobarb febarbamate heptabarb heptobarbital hexethal hexobarbital methallatal metharbital methitural methohexital methylphenobarbital narcobarbital nealbarbital pentobarbital phenallymal phenobarbital phetharbital primidone probarbital propallylonal propylbarbital proxibarbital reposal secobarbital sigmodal spirobarbital talbutal tetrabamate tetrabarbital thialbarbital thiamylal thiobarbital thiobutabarbital thiopental thiotetrabarbital valofane vinbarbital vinylbital benzodiazepines 2 oxoquazepam 3 hydroxyphenazepam adinazolam alprazolam arfendazam avizafone bentazepam bretazenil bromazepam bromazolam brotizolam camazepam carburazepam chlordiazepoxide ciclotizolam cinazepam cinolazepam clazolam climazolam clobazam clonazepam clonazolam cloniprazepam clorazepate clotiazepam cloxazolam cp 1414s cyprazepam delorazepam demoxepam diazepam diclazepam dimdazenil doxefazepam elfazepam estazolam ethyl carfluzepate ethyl dirazepate ethyl loflazepate etizolam fg 8205 fletazepam flubromazepam flubromazolam fludiazepam flunitrazepam flunitrazolam flurazepam flutazolam flutemazepam flutoprazepam fosazepam gidazepam halazepam haloxazolam iclazepam imidazenil irazepine ketazolam lofendazam lopirazepam loprazolam lorazepam lormetazepam meclonazepam medazepam menitrazepam metaclazepam mexazolam midazolam motrazepam n desalkylflurazepam nifoxipam nimetazepam nitrazepam nitrazepate nitrazolam nordazepam nortetrazepam oxazepam oxazolam phenazepam pinazepam pivoxazepam prazepam premazepam proflazepam pyrazolam qh ii 66 quazepam reclazepam remimazolam rilmazafone ripazepam ro48 6791 ro48 8684 sh 053 r ch3 2 f sulazepam temazepam tetrazepam tolufazepam triazolam triflubazam triflunordazepam ro5 2904 tuclazepam uldazepam zapizolam zolazepam zomebazam carbamates carisbamate carisoprodol clocental cyclarbamate difebarbamate emylcamate ethinamate febarbamate felbamate hexapropymate hydroxyphenamate lorbamate mebutamate meprobamate nisobamate pentabamate phenprobamate procymate styramate tetrabamate tybamate flavonoids 6 methylapigenin ampelopsin dihydromyricetin apigenin baicalein baicalin catechin egc egcg hispidulin linarin luteolin rc ome skullcap constituents e g baicalin wogonin imidazoles etomidate metomidate methoxyetomidate propoxate isopropoxate butomidate iso butomidate sec butomidate cf2 etomidate cf3 etomidate cf3 propoxate flutomidate 2 6 dichloro 3 fluoroetomidate kava constituents 10 methoxyyangonin 11 methoxyyangonin 11 hydroxyyangonin desmethoxyyangonin 11 methoxy 12 hydroxydehydrokavain 7 8 dihydroyangonin kavain 5 hydroxykavain 5 6 dihydroyangonin 7 8 dihydrokavain 5 6 7 8 tetrahydroyangonin 5 6 dehydromethysticin methysticin 7 8 dihydromethysticin yangonin monoureides acecarbromal apronal apronalide bromisoval carbromal capuride ectylurea neurosteroids acebrochol allopregnanolone brexanolone alfadolone alfaxalone 3α androstanediol androstenol androsterone certain anabolic androgenic steroids cholesterol cortisol hydrocortisone dhdoc 3α dhp 5α dhp 5β dhp dht etiocholanolone etx 155 ganaxolone hydroxydione lpcn 1154 minaxolone nora 520 org 20599 org 21465 p1 185 posovolone prax 114 pregnanolone eltanolone progesterone renanolone sage 105 sage 324 sage 516 sage 689 sage 872 testosterone thdoc zuranolone nonbenzodiazepines cyclopyrrolones eszopiclone pagoclone pazinaclone suproclone suriclone zopiclone imidazopyridines alpidem ds 1 necopidem saripidem zolpidem pyrazolopyrimidines divaplon fasiplon indiplon lorediplon ocinaplon panadiplon taniplon zaleplon others adipiplon axs 17 baer 101 azd 7325 cgs 8216 cgs 9896 cgs 13767 cgs 20625 cl 218 872 cp 615 003 ctp 354 elb 139 enx 102 tpa 023b gbld 345 imepitoin jm 1232 l 838 417 lirequinil ro41 3696 miltirone rosmariquinone ns 2664 ns 2710 ns 11394 ns 11821 pipequaline rod 188 rwj 51204 sb 205 384 sx 3228 tgsc01aa tp 003 tpa 023 tp 13 u 89843a u 90042 viqualine y 23684 phenols cipepofol fospropofol propofol propofol hemisuccinate thymol piperidinediones glutethimide methyprylon piperidione pyrithyldione pyrazolopyridines cartazolate etazolate ici 190 622 tracazolate quinazolinones afloqualone cloroqualone diproqualone etaqualone mebroqualone mecloqualone methaqualone methylmethaqualone nitromethaqualone sl 164 volatiles gases acetone acetophenone acetylglycinamide chloral hydrate aliflurane benzene butane butylene centalun chloral chloral betaine chloral hydrate chloroform cryofluorane desflurane dichloralphenazone dichloromethane diethyl ether enflurane ethyl chloride ethylene fluroxene gasoline halopropane halothane isoflurane kerosine methoxyflurane methoxypropane nitric oxide nitrogen nitrous oxide norflurane paraldehyde propane propylene roflurane sevoflurane synthane teflurane toluene trichloroethane methyl chloroform trichloroethylene vinyl ether others unsorted 3 hydroxybutanal α emtbl aa 29504 alogabat avermectins e g ivermectin bromide compounds e g lithium bromide potassium bromide sodium bromide carbamazepine chloralose chlormezanone clomethiazole darigabat deabl deuterated etifoxine dihydroergolines e g dihydroergocryptine dihydroergosine dihydroergotamine ergoloid dihydroergotoxine ds2 efavirenz etazepine etifoxine fenamates e g flufenamic acid mefenamic acid niflumic acid tolfenamic acid fluoxetine flupirtine hopantenic acid krm ii 81 lanthanum lavender oil lignans e g 4 o methylhonokiol honokiol magnolol obovatol loreclezole menthyl isovalerate validolum monastrol nezavist dcuk oet nicotinic acid nicotinamide ntx 1955 ro 7308480 org 25 435 phenytoin propanidid retigabine ezogabine safranal seproxetine stiripentol sulfonylalkanes e g sulfonmethane sulfonal tetronal trional terpenoids e g borneol topiramate valerian constituents e g isovaleric acid isovaleramide valerenic acid valerenol unsorted benzodiazepine site positive modulators α pinene mrk 409 mk 0343 tcs 1105 tcs 1205 see also receptor signaling modulators gaba receptor modulators gaba metabolism transport modulators v t e ionotropic glutamate receptor modulators ampar tooltip α amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid receptor agonists main site agonists 5 fluorowillardiine acromelic acid acromelate ampa boaa domoic acid glutamate ibotenic acid proline quisquali...
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