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moving overseas latest stories climate change and energy 23 hours the problem with plug in hybrids their drivers artificial intelligence 2 days how adobe s bet on non exploitative ai is paying off artificial intelligence 5 days apple researchers explore dropping siri phrase listening with ai instead biotechnology and health 6 days how scientists traced a mysterious covid case back to six toilets artificial intelligence 3 days the tech industry can t agree on what open source ai means that s a problem artificial intelligence 2 days ai could make better beer here s how biotechnology and health 7 days this startup wants to fight growing global dengue outbreaks with drones biotechnology and health 1 week the quest to legitimize longevity medicine collection most popular previous slide next slide artificial intelligence large language models can do jaw dropping things but nobody knows exactly why and that s a problem figuring it out is one of the biggest scientific puzzles of our time and a crucial step towards controlling more powerful future models artificial intelligence openai teases an amazing new generative video model called sora the firm is sharing sora with a small group of safety testers but the rest of us will have to wait to learn more artificial intelligence google s gemini is now in everything here s how you can try it out gmail docs and more will now come with gemini baked in but europeans will have to wait before they can download the app biotechnology and health this baby with a head camera helped teach an ai how kids learn language a neural network trained on the experiences of a single young child managed to learn one of the core components of language how to match words to the objects they represent culture meet the divers trying to figure out how deep humans can go figuring out how the human body can withstand underwater pressure has been a problem for over a century but a ragtag band of divers is experimenting with hydrogen to find out artificial intelligence google deepmind s new generative model makes super mario like games from scratch genie learns how to control games by watching hours and hours of video it could help train next gen robots too business why the world s biggest ev maker is getting into shipping byd has become so popular abroad that the company now needs its own fleet of boats to meet demand climate change and energy harvard has halted its long planned atmospheric geoengineering experiment the decision follows years of controversy and the departure of one of the program s key researchers artificial intelligence an openai spinoff has built an ai model that helps robots learn tasks like humans but can it graduate from the lab to the warehouse floor artificial intelligence the ai act is done here s what will and won t change the hard work starts now today s newsletter the latest from the checkup our weekly biotech and health email how scientists traced a mysterious covid case back to six toilets this week i have a mystery for you it s the story of how a team of researchers traced a covid variant in wisconsin from a wastewater plant to six toilets at a single company but it s also a story about privacy concerns that arise when you use sewers to track rare viruses back to their source that virus likely came from a single employee who happened to be shedding an enormous quantity of a very weird variant the researchers would desperately like to find that person but what if that person doesn t want to be found a few years ago marc johnson a virologist at the university of missouri became obsessed with weird covid variants he was seeing in wastewater samples the ones that caught his eye were odd in a couple of different ways they didn t match any of the common variants and they didn t circulate they would pop up in a single location persist for some length of time and then often disappear a blip johnson found his first blip in missouri it drove me nuts he says i was like what the hell was going on here then he teamed up with colleagues in new york and they found a few more hoping to pin down even more lineages johnson put a call out on twitter now x for wastewater in january 2022 he got another hit in a wastewater sample shipped from a wisconsin treatment plant he and david o connor a virologist at the university of wisconsin started working with state health officials to track the signal from the treatment plant to a pumping station and then to the outskirts of the city one manhole at a time johnson says every time there was a branch in the road we would check which branch the signal was coming from they chased some questionable leads the researchers were suspicious the virus might be coming from an animal at one point o connor took people from his lab to a dog park to ask dog owners for poop samples there were so many red herrings johnson says finally after sampling about 50 manholes the researchers found the manhole the last one on the branch that had the variant they got lucky the only source was this company johnson says their results came out in march in lancet microbe wastewater surveillance might seem like a relatively new phenomenon born of the pandemic but it goes back decades a team of canadian researchers outlines several historical examples in this story in one example a public health official traced a 1946 typhoid outbreak to the wife of a man who sold ice cream at the beach even then the researcher expressed some hesitation the study didn t name the wife or the town and he cautioned that infections probably shouldn t be traced back to an individual except in the presence of an outbreak in a similar study published in 1959 scientists traced another typhoid epidemic to one woman who was then banned from food service and eventually talked into having her gallbladder removed to eliminate the infection such publicity can have a devastating effect on the carrier they remarked in their write up of the case from being a quiet and respected citizen she becomes a social pariah when johnson and o connor traced the virus to that last manhole things got sticky until that point the researchers had suspected these cryptic lineages were coming from animals johnson had even developed a theory involving organic fertilizer from a source further upstream now they were down to a single building housing a company with about 30 employees they didn t want to stigmatize anyone or invade their privacy but someone at the company was shedding an awful lot of virus is it ethical to not tell them at that point johnson wondered o connor and johnson had been working with state health officials from the very beginning they decided the best path forward would be to approach the company explain the situation and ask if they could offer voluntary testing the decision wasn t easy we didn t want to cause panic and say there s a dangerous new variant lurking in our community ryan westergaard the state epidemiologist for communicable diseases at the wisconsin department of health services told nature but they also wanted to try to help the person who was infected the company agreed to testing and 19 of its 30 employees turned up for nasal swabs they were all negative that may mean one of the people who didn t test was carrying the infection or could it mean that the massive covid infection in the gut didn t show up on a nasal swab this is where i would use the shrug emoji if we were doing this over email o connor says at the time the researchers had the ability to test stool samples for the virus but they didn t have approval now they do and they re hoping stool will lead them to an individual infected with one of these strange viruses who can help answer some of their questions johnson has identified about 50 of these cryptic covid variants in wastewater the more i study these lineages the more i am convinced that they are replicating in the gi tract johnson says it wouldn t surprise me at all if that s the only place they were replicating but how far should they go to find these people that s still an open question o connor can imagine a dizzying array of problems that might arise if they did identify an individual shedding one of these rare variants the most plausible hypothesis is that the lineages arise in individuals who have immune disorders that make it difficult for them to eliminate the infection that raises a whole host of other thorny questions what if that person had a compromised immune system due to hiv in addition to the strange covid variant what if that person didn t know they were hiv positive or didn t want to divulge their hiv status what if the researchers told them about the infection but the person couldn t access treatment if you imagine what the worst case scenarios are they re pretty bad o connor says on the other hand o connor says they think there are a lot of these people around the country and the world isn t there also an ethical obligation to try to learn what we can so that we can try to help people who are harboring these viruses he asks now read the rest of the checkup more from mit technology review longevity specialists aim to help people live longer and healthier lives but they have yet to establish themselves as a credible medical field expensive longevity clinics that cater to the wealthy worried well aren t helping jessica hamzelou takes us inside the quest to legitimize longevity medicine drug developers bet big on ai to help speed drug development but when will we see our first generative drug antonio regalado has the story read more from mit technology review s archive the covid pandemic brought the tension between privacy and public health into sharp relief wrote karen hao in 2020 that same year genevieve bell argued that we can reimagine contact tracing in a way that protects privacy in 2021 antonio regalado covered some of the first efforts to track the spread of covid variants using wastewater earlier this year i wrote about using wastewater to track measles from around the web surgeons have transplanted a kidney from a genetically engineered pig into a 62 year old man in boston new york times surgeons transplanted a similar kidney into a brain dead patient in 2021 mit technology review researchers are also looking into how to transplant other organs just a few months ago surgeons connected a genetically engineered pig liver to another brain dead patient mit technology review the fda has approved a new gene therapy for a rare but fatal genetic disorder in children its 4 25 million price tag will make it the world s most expensive medicine but it promises to give children with the disease a shot at a normal life cnn read antonio regalado s take on the curse of the costliest drug mit technology review people who practice intermittent fasting have an increased risk of dying of heart disease according to new research presented at the american heart association meeting in chicago there are of course caveats washington post and stat some parents aren t waiting to give their young kids the new miracle drug to treat cystic fibrosis they re starting the treatment in utero the atlantic sign up to get the checkup weekly in your inbox enter your email sign up for free more newsletters features longread culture 1 month meet the divers trying to figure out how deep humans can go figuring out how the human body can withstand underwater pressure has been a problem for over a century but a ragtag band of divers is experimenting with hydrogen to find out computing inside the hunt for new physics at the world s largest particle collider the large hadron collider hasn t seen any new particles since the discovery of the higgs boson in 2012 here s what researchers are trying to do about it climate change and energy why hydrogen is losing the race to power cleaner cars batteries are dominating zero emissions vehicles and the fuel has better uses elsewhere artificial intelligence i used generative ai to turn my story into a comic and you can too by pulling together several different generative models into an easy to use package controlled with the push of a button lore machine heralds the arrival of one click ai biotechnology and health an ai driven factory of drugs claims to have hit a big milestone insilico is part of a wave of companies betting on ai as the next amazing revolution in biology biotechnology and health the next generation of mrna vaccines is on its way adding a photocopier gene to mrna vaccines could make them last longer and curb side effects collection what s next mit technology review s what s next series looks across industries trends and technologies to give you a first look at the future previous slide next slide climate change and energy what s next for offshore wind new projects and financial headwinds will make 2024 a bumpy year for the industry artificial intelligence what s next for robotaxis in 2024 in addition to restoring public trust robotaxi companies need to prove that their business models can compete with uber and taxis artificial intelligence what s next for ai in 2024 our writers look at the four hot trends to watch out for this year policy what s next for ai regulation in 2024 the coming year is going to see the first sweeping ai laws enter into force with global efforts to hold tech companies accountable computing what s next for the world s fastest supercomputers scientists have begun running experiments on frontier the world s first official exascale machine while facilities worldwide build other machines to join the ranks policy what s next for china s digital currency china s government has struggled to find uses for e cny inside of china now it s hoping to use it to challenge the us dominated international financial system space what s next for the moon robots and then humans are going back to the lunar surface here s what they ll be doing magazine our new issue march april 2024 the hidden worlds issue using technology to explore and expose hidden worlds from enabling deeper dives into ocean depths to journeying to one of jupiter s orbiting bodies to pushing the boundaries of particle physics plus wearables for wildlife wi fi sensing and a reconsideration of luddites read now more issues culture meet the divers trying to figure out how deep humans can go figuring out how the human body can withstand underwater pressure has been a problem for over a century but a ragtag band of divers is experimenting with hydrogen to find out computing inside the hunt for new physics at the world s largest particle collider the large hadron collider hasn t seen any new particles since the discovery of the higgs boson in 2012 here s what researchers are trying to do about it space the search for extraterrestrial life is targeting jupiter s icy moon europa nasa s europa clipper mission will travel to one of jupiter s largest moons to look for evidence of conditions that could support life climate change and energy how tracking animal movement may save the plan...
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