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e ivermectin l alanine l proline l serine l threonine mdl 27531 milacemide picolinic acid propofol quisqualamine sarcosine taurine positive modulators alcohols e g brometone chlorobutanol chloretone ethanol alcohol tert butanol 2m2p tribromoethanol trichloroethanol trifluoroethanol alkylbenzene sulfonate anandamide barbiturates e g pentobarbital sodium thiopental chlormethiazole d12 116 dihydropyridines e g nicardipine etomidate ginseng constituents e g ginsenosides e g ginsenoside rf glutamic acid glutamate ivermectin ketamine neuroactive steroids e g alfaxolone pregnenolone eltanolone pregnenolone acetate minaxolone org 20599 nitrous oxide penicillin g propofol tamoxifen tetrahydrocannabinol triclofos tropeines e g atropine bemesetron cocaine ly 278584 tropisetron zatosetron volatiles gases e g chloral hydrate chloroform desflurane diethyl ether ether enflurane halothane isoflurane methoxyflurane sevoflurane toluene trichloroethane methyl chloroform trichloroethylene xenon zinc antagonists 2 aminostrychnine 2 nitrostrychnine 4 phenyl 4 formyl n methylpiperidine αembtl bicuculline brucine cacotheline caffeine colchicine colubrine cyanotriphenylborate dendrobine diaboline endocannabinoids e g 2 ag anandamide aea gaboxadol thip gelsemine iso thaz isobutyric acid isonipecotic acid isostrychnine laudanosine n methylbicuculline n methylstrychnine n n dimethylmuscimol nipecotic acid pitrazepin pseudostrychnine quinolines e g 4 hydroxyquinoline 4 hydroxyquinoline 3 carboxylic acid 5 7 ciqa 7 ciq 7 tfq 7 tfqa ru 5135 sinomenine strychnine thaz thiocolchicoside tutin negative modulators amiloride benzodiazepines e g bromazepam clonazepam diazepam flunitrazepam flurazepam corymine cyanotriphenylborate daidzein dihydropyridines e g nicardipine nifedipine nitrendipine furosemide genistein ginkgo constituents e g bilobalide ginkgolides e g ginkgolide a ginkgolide b ginkgolide c ginkgolide j ginkgolide m imipramine nbqx neuroactive steroids e g 3α androsterone sulfate 3β androsterone sulfate deoxycorticosterone dhea sulfate pregnenolone sulfate progesterone opioids e g codeine dextromethorphan dextrorphan levomethadone levorphanol morphine oripavine pethidine thebaine picrotoxin i e picrotin and picrotoxinin pmba riluzole tropeines e g bemesetron ly 278584 tropisetron zatosetron verapamil zinc nmdar tooltip n methyl d aspartate receptor see here instead transporter blockers glyt1 tooltip sodium and chloride dependent glycine transporter 1 acppb alx 5407 nfps asp2535 bitopertin rg1678 ro4917838 cp 802079 ethanol alcohol glycyldodecylamide gsk1018921 iclepertin ly 2365109 mardepodect org 24598 org 25935 sch 900435 pesampator biib 104 pf 04958242 pf 03463275 sarcosine sng 12 synapsinae ssr 103 800 ssr 504 734 tilapertin glyt2 tooltip glycine transporter 2 alx 1393 amoxapine ethanol alcohol nagly opiranserin vvz 149 org 25543 vvz 368 see also receptor signaling modulators gaba receptor modulators gaba a receptor positive modulators ionotropic glutamate receptor modulators v t e ion channel modulators calcium vdccs tooltip voltage dependent calcium channels blockers l type selective dihydropyridines amlodipine telmisartan and indapamide aranidipine azelnidipine barnidipine clevidipine cronidipine darodipine dexniguldipine elgodipine elnadipine felodipine flordipine furnidipine iganidipine isradipine lacidipine lemildipine lercanidipine levamlodipine levniguldipine manidipine mepirodipine mesudipine nicardipine nifedipine niguldipine niludipine nilvadipine nimodipine nisoldipine nitrendipine olradipine oxodipine palonidipine pranidipine ryodipine riodipine sagandipine sornidipine teludipine tiamdipine trombodipine vatanidipine diltiazem derivatives clentiazem diltiazem iprotiazem nictiazem siratiazem phenylalkylamines anipamil dagapamil devapamil dexverapamil emopamil etripamil falipamil gallopamil levemopamil nexopamil norverapamil ronipamil tiapamil verapamil others ah 1058 brinazarone budiodarone celivarone cyproheptadine dronedarone fantofarone sr 33805 tetrahydropalmatine n type selective ω conotoxins ω conotoxin gvia caroverine huwentoxin xvi leconotide ω conotoxin cvid pd 173212 ralfinamide safinamide z160 ziconotide ω conotoxin mviia p type selective ω agatoxin iva ω agatoxin ivb r type selective snx 482 t type selective abt 639 ml 218 niflumic acid nnc 55 0396 protx i z944 zonisamide non selective ω agatoxin tk ω conotoxin mviic benidipine bepridil cilnidipine cinnarizine dotarizine efonidipine flunarizine lamotrigine levetiracetam lomerizine loperamide mibefradil np078585 ruthenium red trox 1 α 2 δ subunit selective gabapentinoids 4 methylpregabalin arbaclofen arbaclofen placarbil atagabalin baclofen gabapentin gabapentin enacarbil imagabalin mirogabalin pd 200 347 pd 217 014 pd 299 685 phenibut pregabalin others unsorted bencyclane berbamine bevantolol canadine carboxyamidotriazole cycleanine dauricine dimeditiapramine diproteverine enpiperate eperisone elpetrigine ethadione ethanol alcohol ethosuximide fasudil fendiline fostedil imepitoin jtv 519 lidoflazine magnesium manoalide mesuximide monatepil naftopidil ochratoxin a osthol otilonium bromide paramethadione phensuximide pinaverium bromide prenylamine rhynchophylline sesamodil silperisone sipatrigine terodiline tetrandrine tolperisone trimethadione valperinol activators l type selective bay k8644 potassium vgkcs tooltip voltage gated potassium channels blockers 3 4 diaminopyridine amifampridine 4 aminopyridine fampridine dalfampridine adekalant almokalant amiodarone azimilide bretylium bunaftine charybdotoxin clamikalant conotoxins dalazatide dendrotoxin dofetilide dronedarone e 4031 hanatoxin hgetx1 hstx1 ibutilide inakalant kaliotoxin linopirdine lolitrem b maurotoxin nifekalant notoxin paxilline pinokalant quinidine shk 186 sotalol tedisamil terikalant tetraethylammonium vernakalant herg kcnh2 k v 11 1 specific ajmaline amiodarone ammtx3 astemizole azaspiracid azd1305 azimilide bedaquiline bekm 1 bmtx3 brl 32872 chlorpromazine cisapride clarithromycin darifenacin dextropropoxyphene diallyl trisulfide domperidone e 4031 ergtoxins erythromycin gigactonine haloperidol ketoconazole norpropoxyphene orphenadrine pimozide pnu 282 987 promethazine quinidine ranolazine roxithromycin sertindole solifenacin tamulotoxin terodiline terfenadine thioridazine tolterodine vanoxerine vernakalant kcnq k v 7 specific linopirdine spooky toxin sstx xe 991 activators kcnq k v 7 specific azetukalner encukalner cb03 154 fluoxakalner flupirtine opakalim pynegabine retigabine ezogabine irks tooltip inwardly rectifying potassium channel blockers k atp tooltip atp sensitive potassium channel specific acetohexamide carbutamide chlorpropamide glibenclamide glyburide glibornuride glicaramide gliclazide glimepiride glipizide gliquidone glisoxepide glyclopyramide glycyclamide metahexamide mitiglinide nateglinide repaglinide tolazamide tolbutamide girk tooltip g protein coupled inwardly rectifying potassium channel specific barium caramiphen cloperastine clozapine dextromethorphan ethosuximide ifenprodil tertiapin tipepidine activators k atp tooltip atp sensitive potassium channel specific aprikalim bimakalim cromakalim diazoxide emakalim levcromakalim mazokalim minoxidil minoxidil sulfate naminidil nicorandil pinacidil rilmakalim sarakalim girk tooltip g protein coupled inwardly rectifying potassium channel specific ml 297 vu0456810 k ca tooltip calcium activated potassium channel blockers bk ca specific ethanol alcohol gal 021 activators bk ca specific chlorzoxazone estradiol flindokalner flufenamic acid isopimaric acid meclofenamic acid niflumic acid nimesulide riluzole rottlerin mallotoxin tamoxifen tolfenamic acid vsn16r k2ps tooltip tandem pore domain potassium channel blockers 12 o tetradecanoylphorbol 13 acetate arachidonic acid fluoxetine norfluoxetine activators riluzole sodium vgscs tooltip voltage gated sodium channels blockers antianginals ranolazine antiarrhythmics class i ajmaline aprindine disopyramide dronedarone encainide flecainide lidocaine lorajmine lorcainide mexiletine moricizine pilsicainide prajmaline procainamide propafenone quinidine sparteine tocainide anticonvulsants acetylpheneturide carbamazepine cenobamate chlorphenacemide elpetrigine eslicarbazepine acetate ethotoin fosphenytoin lamotrigine lacosamide licarbazepine mephenytoin oxcarbazepine oxitriptyline phenacemide pheneturide phenytoin relutrigine rufinamide sipatrigine topiramate sodium valproate valnoctamide valproate pivoxil valproate semisodium valproic acid valpromide zonisamide local anesthetics p fbt amylocaine articaine benzocaine bupivacaine levobupivacaine ropivacaine butacaine butamben chloroprocaine cinchocaine cocaine cyclomethycaine dimethocaine diphenhydramine etidocaine hexylcaine iontocaine lidocaine mepivacaine meprylcaine metabutoxycaine orthocaine piperocaine prilocaine procaine propoxycaine proxymetacaine risocaine tetracaine trimecaine analgesics azd 3161 dsp 2230 funapide gdc 0276 nktr 171 pf 04531083 pf 05089771 ralfinamide raxatrigine rg7893 gdc 0287 suzetrigine toxins conotoxins neosaxitoxin saxitoxin tetrodotoxin zetekitoxin ab others buprenorphine evenamide menthol mint safinamide tricyclic antidepressants activators aconitine atracotoxins ω atracotoxin robustoxin versutoxin batrachotoxin ciguatoxins grayanotoxins poneratoxin enac tooltip epithelial sodium channel blockers amiloride benzamil triamterene activators solnatide asics tooltip acid sensing ion channel blockers a 317567 amiloride aspirin ibuprofen pctx1 chloride caccs tooltip calcium activated chloride channel blockers crofelemer dids ethacrynic acid flufenamic acid fluoxetine furosemide glibenclamide mefloquine mibefradil niflumic acid activators carbachol cftr tooltip cystic fibrosis transmembrane conductance regulator blockers glibenclamide lonidamine piretanide activators 1 7 phenanthroline 1 10 phenanthroline 4 7 phenanthroline 7 8 benzoquinoline ivacaftor phenanthridine unsorted blockers bumetanide flufenamic acid meclofenamic acid mefenamic acid mepacrine niflumic acid talniflumate tolfenamic acid trifluoperazine others trps tooltip transient receptor potential channels see here instead lgics tooltip ligand gated ion channels see here instead see also receptor signaling modulators transient receptor potential channel modulators v t e ionotropic glutamate receptor modulators ampar tooltip α amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid receptor agonists main site agonists 5 fluorowillardiine acromelic acid acromelate ampa boaa domoic acid glutamate ibotenic acid proline quisqualic acid willardiine positive allosteric modulators aniracetam cyclothiazide cx 516 cx 546 cx 614 farampator cx 691 org 24448 cx 717 cx 1739 cx 1942 diazoxide hydrochlorothiazide hctz idra 21 ly 392098 ly 395153 ly 404187 ly 451646 ly 503430 mibampator ly 451395 nooglutyl org 26576 oxiracetam pepa pesampator biib 104 pf 04958242 piracetam pramiracetam s 18986 tulrampator s 47445 cx 1632 antagonists acea 1011 atpo becampanel caroverine cnqx dasolampanel dnqx fanapanel mpqx gams kaitocephalin kynurenic acid kynurenine licostinel acea 1021 nbqx pnqx selurampanel tezampanel theanine topiramate ym90k zonampanel negative allosteric modulators barbiturates e g pentobarbital sodium thiopental cyclopropane enflurane ethanol alcohol evans blue gyki 52466 gyki 53655 halothane irampanel isoflurane perampanel pregnenolone sulfate rap 219 sevoflurane talampanel unknown unsorted antagonists minocycline kar tooltip kainate receptor agonists main site agonists 5 bromowillardiine 5 iodowillardiine acromelic acid acromelate ampa atpa domoic acid glutamate ibotenic acid kainic acid ly 339434 proline quisqualic acid sym 2081 positive allosteric modulators cyclothiazide diazoxide enflurane halothane isoflurane antagonists acea 1011 cnqx dasolampanel dnqx gams kaitocephalin kynurenic acid licostinel acea 1021 ly 382884 nbqx ns102 selurampanel tezampanel theanine topiramate ubp 302 negative allosteric modulators barbiturates e g pentobarbital sodium thiopental enflurane ethanol alcohol evans blue ns 3763 pregnenolone sulfate nmdar tooltip n methyl d aspartate receptor agonists main site agonists amaa aspartate glutamate homocysteic acid l hca homoquinolinic acid ibotenic acid nmda proline quinolinic acid tetrazolylglycine theanine glycine site agonists β fluoro d alanine acbd acc acpc acpd ak 51 apimostinel nrx 1074 b6b21 ccg d alanine d cycloserine d serine dhpg dimethylglycine glycine ha 966 l 687 414 l alanine l serine milacemide neboglamine nebostinel rapastinel glyx 13 sarcosine polyamine site agonists neomycin spermidine spermine other positive allosteric modulators 24 s hydroxycholesterol dhea tooltip dehydroepiandrosterone prasterone dhea sulfate prasterone sulfate epipregnanolone sulfate plazinemdor pregnenolone sulfate sage 201 sage 301 sage 718 antagonists competitive antagonists ap5 apv ap7 cgp 37849 cgp 39551 cgp 39653 cgp 40116 cgs 19755 cpp kaitocephalin ly 233053 ly 235959 ly 274614 mdl 100453 midafotel d cppene npc 12626 npc 17742 pbpd peaqx perzinfotel ppda sdz 220581 selfotel glycine site antagonists 4 cl kyn av 101 5 7 dcka 7 cka acc acea 1011 acea 1328 apimostinel nrx 1074 av 101 carisoprodol cgp 39653 cnqx d cycloserine dnqx felbamate gavestinel gv 196771 harkoseride kynurenic acid kynurenine l 689560 l 701324 licostinel acea 1021 lu 73068 mdl 105519 meprobamate mrz 2 576 pnqx rapastinel glyx 13 zd 9379 polyamine site antagonists arcaine co 101676 diaminopropane diethylenetriamine huperzine a putrescine uncompetitive pore blockers mostly dizocilpine site 2 mdp 3 ho pcp 3 meo pce 3 meo pcmo 3 meo pcp 4 meo pcp 8a pdhq 18 mc α endopsychosin alaproclate alazocine skf 10047 amantadine aptiganel argiotoxin 636 arketamine arl 12495 arl 15896 ar arl 16247 budipine cns 5161 coronaridine delucemine nps 1506 dexoxadrol dextrallorphan dextromethadone dextromethorphan dextrorphan dieticyclidine diphenidine dizocilpine ephenidine esketamine etoxadrol eticyclidine f 17475 fluorolintane gacyclidine ibogaine ibogamine indantadol ketamine ketobemidone lanicemine levomethadone levomethorphan levomilnacipran levorphanol loperamide memantine methadone methorphan methoxetamine methoxphenidine milnacipran morphanol nefa neramexane nitromemantine noribogaine norketamine orphenadrine pcpr pd 137889 pethidine meperidine phencyclamine phencyclidine propoxyphene remacemide rhynchophylline rimantadine rolicyclidine sabeluzole tabernanthine tenocyclidine tiletamine tramadol ifenprodil nr2b site antagonists besonprodil buphenine nylidrin co 101244 pd 174494 eliprodil haloperidol isoxsuprine radiprodil rgh 896 rislenemdaz cerc 301 mk 0657 ro 8 4304 ro 25 6981 safaprodil traxoprodil cp 101606 nr2a selective antagonists mpx 004 mpx 007 tcn 201 tcn 213 cations hydrogen magnesium zinc alcohols volatile anesthetics related benzene butane chloroform cyclopropane desflurane diethyl ether enflurane ethanol alcohol halothane hexanol isoflurane methoxyflurane nitrous oxide octanol se...
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