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metabolite wikipedia jump to content main menu main menu move to sidebar hide navigation main page contents current events random article about wikipedia contact us contribute help learn to edit community portal recent changes upload file special pages search search appearance donate create account log in personal tools donate create account log in contents move to sidebar hide top 1 see also 2 references 3 external links toggle the table of contents metabolite 41 languages العربية azərbaycanca bosanski català čeština dansk deutsch ελληνικά esperanto español eesti فارسی français galego עברית bahasa indonesia ido italiano 日本語 한국어 latina latviešu മലയാളം bahasa melayu nederlands norsk bokmål polski português română русский srpskohrvatski српскохрватски simple english slovenčina slovenščina српски srpski svenska ไทย türkçe українська tiếng việt 中文 edit links article talk english read edit view history tools tools move to sidebar hide actions read edit view history general what links here related changes upload file permanent link page information cite this page get shortened url print export download as pdf printable version in other projects wikimedia commons wikibooks wikidata item appearance move to sidebar hide from wikipedia the free encyclopedia intermediate or end product of metabolism in biochemistry a metabolite is an intermediate or end product of metabolism 1 the term is usually used for small molecules metabolites have various functions including fuel structure signaling stimulatory and inhibitory effects on enzymes catalytic activity of their own usually as a cofactor to an enzyme defense and interactions with other organisms e g pigments odorants and pheromones a primary metabolite is directly involved in normal growth development and reproduction ethylene exemplifies a primary metabolite produced large scale by industrial microbiology a secondary metabolite is not directly involved in those processes but usually has an important ecological function examples include antibiotics and pigments such as resins and terpenes etc some antibiotics use primary metabolites as precursors such as actinomycin which is created from the primary metabolite tryptophan some sugars are metabolites such as fructose or glucose which are both present in the metabolic pathways examples of primary metabolites produced by industrial microbiology include 2 class example alcohol ethanol amino acids glutamic acid aspartic acid nucleotides guanosine monophosphate antioxidants isoascorbic acid organic acids acetic acid lactic acid polyols glycerol vitamins riboflavin the metabolome forms a large network of metabolic reactions where outputs from one enzymatic chemical reaction are inputs to other chemical reactions metabolites from chemical compounds whether inherent or pharmaceutical form as part of the natural biochemical process of degrading and eliminating the compounds 3 the rate of degradation of a compound is an important determinant of the duration and intensity of its action understanding how pharmaceutical compounds are metabolized and the potential side effects of their metabolites is an important part of drug discovery 4 see also edit antimetabolite intermediary metabolism also called intermediate metabolism metabolic control analysis metabolomics the study of global metabolite profiles in a system cell tissue or organism under a given set of conditions metabolic pathway volatile organic compound references edit venes donald ed 1940 taber s cyclopedic medical dictionary 23 ed philadelphia f a davis published 2017 p 1510 isbn 9780803659407 retrieved 16 march 2020 metabolite any product of metabolism cite book isbn date incompatibility help demain arnold l december 1980 microbial production of primary metabolites naturwissenschaften 67 12 582 587 bibcode 1980nw 67 582d doi 10 1007 bf00396537 pmid 7231563 s2cid 21590956 archived from the original on 2019 09 12 retrieved 2025 08 23 cite journal cs1 maint bot original url status unknown link harris edward d biochemical facts behind the definition and properties of metabolites pdf fda gov united states food and drug administration archived from the original pdf on december 16 2003 retrieved 28 april 2017 obach r scott esbenshade timothy a april 2013 pharmacologically active drug metabolites impact on drug discovery and pharmacotherapy pharmacological reviews 65 2 578 640 doi 10 1124 pr 111 005439 pmid 23406671 s2cid 720243 external links edit look up metabolite in wiktionary the free dictionary media related to metabolites at wikimedia commons authority control databases international gnd national united states france bnf data czech republic israel other yale lux retrieved from https en wikipedia org w index php title metabolite oldid 1333668930 category metabolites hidden categories cs1 errors isbn date cs1 maint bot original url status unknown articles with short description short description is different from wikidata commons category link is on wikidata this page was last edited on 19 january 2026 at 02 22 utc text is available under the creative commons attribution sharealike 4 0 license additional terms may apply by using this site you agree to the terms of use and privacy policy wikipedia is a registered trademark of the wikimedia foundation inc a non profit organization privacy policy about wikipedia disclaimers contact wikipedia legal safety contacts code of conduct developers statistics cookie statement mobile view search search toggle the table of contents metabolite 41 languages add topic
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