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diberal wikipedia jump to content main menu main menu move to sidebar hide navigation main page contents current events random article about wikipedia contact us contribute help learn to edit community portal recent changes upload file special pages search search appearance donate create account log in personal tools donate create account log in contents move to sidebar hide top 1 pharmacology toggle pharmacology subsection 1 1 isomer 1 2 isomer 2 see also 3 references toggle the table of contents diberal 2 languages اردو 中文 edit links article talk english read edit view history save tools tools move to sidebar hide actions read edit view history save general what links here related changes upload file permanent link page information cite this page get shortened url switch to legacy parser print export download as pdf printable version in other projects wikidata item appearance move to sidebar hide from wikipedia the free encyclopedia redirected from 5 1 3 dimethylbutyl 5 ethylbarbituric acid diberal 1 names iupac name 5 ethyl 5 4 methylpentan 2 yl 1 3 diazinane 2 4 6 trione other names dmbb 5 ethyl 5 1 3 dimethylbutyl barbituric acid 5 1 3 dimethylbutyl 5 ethylbarbituric acid identifiers cas number 2964 06 9 3d model jsmol interactive image chemspider 17079 pubchem cid 18079 unii 31e1hc8i46 comptox dashboard epa dtxsid301031188 inchi inchi 1s c12h20n2o3 c1 5 12 8 4 6 7 2 3 9 15 13 11 17 14 10 12 16 h7 8h 5 6h2 1 4h3 h2 13 14 15 16 17 key kxhlanwwtksomw uhfffaoysa n smiles ccc1 c o nc o nc1 o c c cc c c properties chemical formula c 12 h 20 n 2 o 3 molar mass 240 303 g mol 1 except where otherwise noted data are given for materials in their standard state at 25 c 77 f 100 kpa infobox references chemical compound diberal also known as 5 1 3 dimethylbutyl 5 ethylbarbituric acid or dmbb is an atypical barbiturate this compound can be either convulsant or anticonvulsant depending on which enantiomer is used pharmacology edit diberal unlike most barbiturates can have convulsant actions this is uncommon as barbiturates typically enhance the function of gaba as allorestic modulators and agonists at higher doses 2 therefore having anticonvulsant properties depending on which isomer is used it can have either convulsant or anticonvulsant actions the different pharmacological profile between isomers is thought to be due to the differences in the formation of hydrogen bonds at the binding sites 3 isomer edit dmbb is the atypical enantiomer of diberal it is atypical in the means that it has convulsant action unlike most barbiturate drugs 4 isomer edit unlike dmbb the isomer is similar to most barbiturates by having anticonvulsant action it has been found that administration of dmbb reverses the convulsant actions of dmbb 3 dmbb is slightly more potent than pentobarbital in its depressant properties 5 see also edit cheb mcn 481 references edit diberal pubchem u s national library of medicine suddock jt kent kj regina ac cain md 2024 barbiturate toxicity statpearls treasure island fl statpearls publishing pmid 29763050 1 2 ho ik harris ra 1981 mechanism of action of barbiturates pdf annual review of pharmacology and toxicology 21 83 111 doi 10 1146 annurev pa 21 040181 000503 pmid 6263177 archived from the original pdf on 2024 03 10 retrieved 2024 01 29 desai r savechenkov py zolkowska d ge rl rogawski ma bruzik ks et al november 2015 contrasting actions of a convulsant barbiturate and its anticonvulsant enantiomer on the α1 β3 γ2l gabaa receptor account for their in vivo effects the journal of physiology 593 22 4943 4961 doi 10 1113 jp270971 pmc 4650410 pmid 26378885 downes h perry rs ostlund re karler r december 1970 a study of the excitatory effects of barbiturates the journal of pharmacology and experimental therapeutics 175 3 692 699 pmid 5489924 v t e convulsants gaba receptor antagonists bicuculline bicyclic phosphates tbps tbpo iptbo bidn bupleurotoxin chlorophenylsilatrane cicutoxin cloflubicyne coriamyrtin calycanthine dihydropicrotoxinin dmcm ebob endosulfan fg 7142 fipronil flurothyl gabazine oenanthotoxin pentylenetetrazol phenylsilatrane picrotoxin p cn tbob p ncs tbob rdx tbob tetramethylenedisulfotetramine thujone trimethylolpropane phosphite tutin gaba synthesis inhibitors 3 mercaptopropionic acid 4 deoxypyridoxine allylglycine crimidine decaborane ginkgotoxin isoniazid pentaborane thiocarbohydrazide toxopyrimidine glycine receptor antagonists coriamyrtin dendrobine picrotoxin strychnine tutin glutamate receptor agonists ampa domoic acid kainic acid nmda quisqualic acid tetrazolylglycine glutamine synthetase inhibitors arsinothricin glufosinate methionine sulfoximine convulsant barbiturates cheb diberal dmbb mcn 481 other 2 2 3 3 tetrafluoropropyl trifluoromethyl ether bromocamphor camphor faz 4 fluoroethyl fluoroacetate leptodactyline mc 2973 methyl fluoroacetate nitrocyclohexane thebaine retrieved from https en wikipedia org w index php title diberal oldid 1335731780 category convulsant barbiturates hidden categories articles without inchi source articles without ebi source articles without kegg source articles containing unverified chemical infoboxes chembox image size set articles with short description short description matches wikidata this page was last edited on 30 january 2026 at 22 07 utc page was rendered with parsoid text is available under the creative commons attribution sharealike 4 0 license additional terms may apply by using this site you agree to the terms of use and privacy policy wikipedia is a registered trademark of the wikimedia foundation inc a non profit organization privacy policy about wikipedia disclaimers contact wikipedia legal safety contacts code of conduct developers statistics cookie statement mobile view search search toggle the table of contents diberal 2 languages add topic
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