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description=BRENDA - The Comprehensive Enzyme Information System;
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brenda enzyme database leibniz institute dsmz dsmz digital diversity login enzyme ligand contains search enzyme or ligand go sparql classic view all enzymes enzyme history brenda support any feedback please rate this page index php 0 150 send feedback brenda support all fields enzyme ligand organism activating compound amino acid sequence application cas registry number cloned commentary cofactor crystallization commentary disease diagnostics ec number enzyme names synonyms expression general information general stability ic50 value inhibitors kcat km mm s kenda ki value mm km value mm ligands localization source tissue metals ions molecular weight da natural product natural substrate natural substrates products substrates organic solvent stability organism oxidation stability pathway pdb id ph optimum ph range ph stability pi value posttranslational modification product protein variants purification commentary reaction reaction type recommended name reference title renatured commentary specific activity micromol min mg storage stability substrate substrates and products substrate subunits synonyms systematic name temperature optimum c temperature range c temperature stability c turnover number 1 s uniprot accession code exact contains begins with ends with use or as wildcard boolean brenda features text based queries full text search advanced search drenda mesh ontology gene search new structure based queries ligand structure search metabolic pathways enzyme structures explorer enzyme classification taxtree protein folding cath scope ontologies visualization enzyme word maps organism word maps genomes functional parameter statistics metabolic pathways prediction membrane helices localization prediction supporting external brenda tissue ontology news brenda strenda 22nd strenda meeting standardization of functional enzyme data september 14 2026 antje jäde this week members of the brenda team will be attending the beilstein strenda commission meeting in rüdesheim germany strenda standards for reporting enzymology data brings together international experts in enzymology biochemistry enzyme nomenclature bioinformatics and related fields to improve the quality and reproducibility of enzyme data reported in the scientific literature read more brenda future new database pipeline paving the way for the future of brenda august 10 2026 mathias krull we are thrilled to announce a complete overhaul of our database update pipeline laying a robust foundation for the future of brenda this next generation architecture drastically improves deployment speed reliability and scalability for all upcoming data releases it is a key milestone on the way of deploying a new brenda website and api latest brenda release release 2026 1 march 4 2026 including 124 new and 750 updated enzyme classes use of this online version of brenda is free under the cc by 4 0 license see terms of use for full details release 2026 1 march 2026 about brenda introduction team expert committee esab iubmb how to cite brenda acknowledgements statistics news social media help support howto tutorial videos faqs survey denbi evaluation download sparql sbml output soap brenda download contribution brenda input submit your paper propose new enzyme to explorenz legal imprint privacy policy license disclaimer curated at member of we value your privacy brenda uses cookies to anonymously track site statistics and to enhance the user expericence by clicking the accept button you consent to the use of cookies for more information visit our privacy policy accept