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Text of the page (random words):
affairs of the heart determined university of arkansas skip to content close search search a z index blackboard learn campus map directory email myapps workday determined and dedicated to arkansas quick links university of arkansas a z index blackboard learn campus map directory email myapps workday search search join selectedindex 1 reset selection on new input add click event to each suggestion const suggestionitems suggestionbox queryselectorall div suggestionitems foreach item item addeventlistener click const selectedterm item getattribute data term searchinput value selectedterm searchform submit window location href https www uark edu search index php searchstudioquery encodeuricomponent selectedterm catch error console error error fetching suggestions error suggestionbox innerhtml error fetching suggestions searchinput addeventlistener keydown event const suggestionitems suggestionbox queryselectorall suggestion item if suggestionitems length 0 return if event key arrowdown event preventdefault selectedindex selectedindex 1 suggestionitems length else if event key arrowup event preventdefault selectedindex selectedindex 1 suggestionitems length suggestionitems length else if event key enter if selectedindex 0 suggestionitems selectedindex event preventdefault searchinput value suggestionitems selectedindex getattribute data term searchform submit highlight the selected suggestion suggestionitems foreach item index if index selectedindex item style backgroundcolor ddd highlight selected item else item style backgroundcolor reset others menu preventing diagnosing and treating cardiovascular disease arkansas and its surrounding states have the highest death rates from cardiovascular disease in the united states research at the university of arkansas seeks to change that affairs of the heart one percent of all live births have some type of heart defect explains morten jensen an associate professor of biomedical engineering at the university of arkansas who specializes in developing innovative medical devices and experimental cardiovascular surgery that s nothing to be alarmed about because you don t see one out of every 100 live births needing surgery the majority of people who have small defects never need to worry about it doctoral student kaitlyn elmer works with jensen in his lab a case in point jensen himself has a leaking pulmonary valve discovered by a colleague who assured him that 60 of adults suffer from the same condition which invites the question if more than half of all adults have a leaky valve is it really a defect or is it supposed to be like that ultimately jensen says many things can go wrong in the development process of the heart and it s one of the imperfect wonders of nature that creates something that is so remarkable it s a design that took 5 billion years to develop to talk to jensen is to be immersed in the mystery and wonder of the human heart its leaky valves its coronary bifurcations and blockages its left ventricle muscles creating five newtons of force every time they open and close the mitral valve which he simulates by grabbing two 500ml plastic bottles and banging them down oh and the word mitral it means shaped like a mitre in latin which is the pointed hat the pope wears when jensen says of the heart it s simple beautiful but incredibly complex it s clear his fascination stems from a deep understanding of its function and mechanics a transformative internship jensen got into the field almost by accident when he was a computer and electrical engineering student in denmark where he was born he was required to do a one semester internship on a research or industry related project he did this with the bioengineering department of aarhus university hospital where he witnessed heart surgeries on humans including a heart transplant the experience set him on an entirely new course i thought it was extremely fascinating with the heart being a pump jensen explained you could look at the heart as a mechanical device adding pressure to fluids and the fluids flowing into the blood vessels jensen earned a master s degree in biomedical engineering at the georgia institute of technology and returned to aarhus for his doctorate in 2015 jensen became just the third engineer in denmark since 1479 to obtain the prestigious doctor of medical science degree which is officially a higher doctorate ranking above a ph d that same year jensen came to the u of a as an arkansas research alliance scholar and is now the principal investigator at the cardiovascular biomechanics laboratory unfortunately he has his work cut out for him cardiovascular disease is the number one killer worldwide while arkansas and its surrounding states have the highest death rates from cardiovascular disease in the united states the others are nearby oklahoma mississippi louisiana and alabama the cblab brings engineers and clinicians together to address conditions such as heart attack stroke heart failure and congenital heart disease while creating novel approaches in the prevention diagnosis and treatment of cardiovascular disease a stent in gel attached to a pressure hose the angle of bifurcation since he saw that first heart transplant jensen has helped contribute intellectual property to nine patent applications this includes development of lifelike artificial tissues to aid medical students in their training spoons to assist with the removal of bladder stones on companion animals and a heart valve created from animal tissues that can be implanted in humans kaitlyn elmer a doctoral student in biomedical engineering from springfield missouri conducts research in jensen s lab elmer and jensen are specifically focused on arterial blockages at a coronary bifurcation where a major artery splits into smaller blood vessels elmer notes that twenty percent of plaque blockages are actually in a bifurcation and since it s branching it s just a weird shape and really difficult for physicians to use conventional methods to treat those she said that normal methods employ a balloon to expand a stent that props the vessel open these constructs are usually cylindrically shaped but the bifurcation typically is not so she and jensen are working with cardiologists to create a stent that is designed to fit in the bifurcation which can have a range of angles this has required development of a computer program to measure the angles of these bifurcations so they can create better designed balloons and stents prototypes are then created and tested in ballistic gel models to see how the stent s shape changes when expanded the project is funded by the american heart association and the technology is promising enough that they applied for two patents through the u of a s technology ventures one for the software program that measures the angle of bifurcation and another for the actual devices vascugenix a company based in little rock specializing in medical devices for interventional cardiology surgery has signed an option agreement with tech ventures that would pave the way for licensing pending further development noah ascher ceo of vascugenix said there is a clear need for a solution in the treatment of bifurcation lesions and it is our company s vision to work with dr jensen to develop manufacture and deliver a comprehensive stent system for addressing this need a better way to detect internal bleeding jensen is also the principal investigator on a recent 1 9 million award from the department of defense to develop a wearable device for the early detection and monitoring of internal or external bleeding jingxian wu and robert saunders hemorrhagic shock is currently the leading cause of preventable death in casualty care settings existing methods often fail to detect blood loss until the onset of shock which can be too late for some patients this makes early detection and management of bleeding related conditions critical to improving survival rates jensen is working with a multi disciplinary team to design a mobile device that can detect blood pressure waveforms which correlate with the volume of blood within the blood vessels and can determine if blood volume is falling due to hemorrhaging this will enable first responders and hospital staff to get more accurate readings earlier and respond with better timed and more precisely calibrated care jensen s work will include jingxian wu a u of a professor of electrical engineering and robert saunders an associate department head of electrical engineering and computer science hanna jensen an assistant professor in the department of surgery at the university of arkansas for medical sciences and course director of the school s cardiovascular module will oversee the translational and clinical phases of the project ultimately their goal is to develop a device that is less than an inch square and sells for less than 100 collaboration is key saunders who teaches a senior design class in the college of engineering has worked with jensen on a range of projects how many wow that s a long list saunders laughs before rattling off a few heated pulse oximeters for people who have bad circulation wheelchair monitors for disabled people an ohm device to determine whether or not an artificial knee has appropriate motion saunders says of jensen he s a great part of the team everybody is really dedicated to the project they re working on they re dedicated to the students around them collaboration is clearly key to jensen s success from witnessing those teams in the aarhus basement to all the adjoining names on his patent applications to his recent research projects in fact one of his closest collaborators is his wife hanna an m d who knew jensen professionally before knowing him personally their research topics were so closely related that they kept presenting at the same sessions of the same conferences her on the medical side him on the engineering hanna jensen i distinctly remember morten walking up to me after one of my first presentations and telling me he could write a program to automatically count the number of activated leukocytes on an intravital microscope video clip something i had spent painstaking months doing manually alone in a dark room as a medical student hanna jensen said i always joke that it was the moment i knew i d marry him the jensens have collaborated on a number of projects including the current dod grant a vector flow imaging study on pediatric patients to create detailed images of the internal structure and blood flow of babies hearts and two children matilda and lukas we figured out we can constantly learn from each other and fill gaps on the continuum of biomedical research hanna explained and we respect each other s areas of expertise so we rarely clash on professional topics we also have distinct roles that work well for us in professional and personal life morten is the idea generator and i am the organizer we both love to be connected and plugged into our professional communities and it s been so rewarding to find collaborators on both the medicine and engineering side we are both at our best as team players plus when a big deadline is looming we can gear the entire family schedule towards making it happen coda in a conversation with jensen he offered a quick tour of the heart showing how blood comes in from the lungs through the left atrium passes through the mitral valve which prevents it from flowing backwards then enters the left ventricle and pushes on to the aorta from there it circulates through the body until it finally returns to the heart through the right ventricle and is sent back to the lungs for more oxygen he concludes so it s pretty neat the way it works he s just got a few more things to fix university of arkansas about apply academics student life research news razorbacks like us on facebook follow us on twitter watch us on youtube see us on instagram connect with us on linkedin 1 university of arkansas 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