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ine discovery medicine is a peer reviewed academic journal indexed in the science citation index expanded sci e of web of science the journal publishes research in the field of medicine with a particular focus on advancing the understanding of physiological and pathological mechanisms in human health and disease as well as on the development improvement and clinical evaluation of strategies for disease prevention diagnosis and treatment it aims to provide a global platform for researchers and clinicians to disseminate impactful findings and to facilitate the continuous advancement of medical research and clinical practice more about discovery medicine about discovery medicine discovery medicine is a peer reviewed academic journal indexed in the science citation index expanded sci e of web of science the journal publishes research in the field of medicine with a particular focus on advancing the understanding of physiological and pathological mechanisms in human health and disease as well as on the development improvement and clinical evaluation of strategies for disease prevention diagnosis and treatment it aims to provide a global platform for researchers and clinicians to disseminate impactful findings and to facilitate the continuous advancement of medical research and clinical practice more about discovery medicine biomarkers and neuroimmune mechanisms in neurodegeneration and neurological disorders professor liang qiao has joined as associate editor in chief of the discovery medicine 2025 journal impact factor updated editorial system migration notice merging cellular mechanisms and translational strategies in chronic disease implementation of image integrity review tool in discovery medicine what led you to become eic editorial board jun li liu editor in chief gene targeting and transgenic overexpression in mice pancreatic islet growth and protection metabolic regulation and the mechanism of diabetes mellitus anne vejux associate editor in chief oxysterols very long chain fatty acids lipid metabolism peroxisomes biotherapies inflammation cancer cell cycle and apoptosis autophagy biological membranes oxidative damage biomarkers neurodegenerative diseases diet brain liang qiao associate editor in chief liver disease gastrointestinal diseases cancer stem cells pre clinical models organoids experimental cancer therapy fatty liver disease animal models of human diseases diana amantea editorial board member cerebral ischemia neuro immune interactions neuroinflammation neuroprotection stroke announcements editorial system migration notice 15 jun 2026 discovery medicine journal identity and submission information 1 may 2026 highlights review 20 jan 2025 neuroinflammation in the post ischemic brain in the presence of amyloid and tau protein ryszard pluta discov med 2025 37 192 1 18 https doi org 10 24976 discov med 202537192 1 download share 222 view s 100 download s 18 citation s editorial 20 sep 2024 antimicrobial resistance a global public health concern that needs perspective combating strategies and new talented antibiotics abdelazeem mohamed algammal payam behzadi discov med 2024 36 188 1911 1913 https doi org 10 24976 discov med 202436188 177 download share 206 view s 60 download s 51 citation s article 20 feb 2024 thermoresponsive and injectable pluronic f127 hydrogel for loading adipose derived mesenchymal stem cells khan sharun shajahan amitha banu merlin mamachan rony s emmanuel rohit kumar obli rajendran vinodhkumar kuldeep dhama abhijit motiram pawde swapan kumar maiti amar pal discov med 2024 36 181 294 307 https doi org 10 24976 discov med 202436181 28 download share 254 view s 97 download s 22 citation s review 20 feb 2024 growth differentiation factor 15 orchestrates inflammation related diseases via macrophage polarization jingjing huang xinhuan ding yuan dong haiyan zhu discov med 2024 36 181 248 255 https doi org 10 24976 discov med 202436181 23 download share 165 view s 127 download s 23 citation s email alert add your e mail address to receive forthcoming issues of this journal subscribe article list latest issue top read systematic review 23 sep 2026 the era of rapid acting antidepressants clinical insights into ketamine esketamine and scopolamine jozélio freire de carvalho eduardo pondé de sena discov med 2026 38 212 3051 3058 https doi org 10 24976 discov med 202638212 235 download share 77 view s 22 download s article 23 sep 2026 tlr3 overexpression attenuates d galn lps induced acute liver injury and is associated with ampk phosphorylation autophagy related changes and irf3 upregulation yi zhang jun zou xiang chen discov med 2026 38 212 3036 3050 https doi org 10 24976 discov med 202638212 234 download share 34 view s 11 download s article 23 sep 2026 lower limb muscle mass parameters predict short term prognosis after endovascular intervention for non thrombotic iliac vein compression syndrome with varicose veins yanqing zhan chenshu li juan wang peng qiu tingmiao wu zhigang wang hui ma hongji pu jinhua zhou wei chen discov med 2026 38 212 3028 3035 https doi org 10 24976 discov med 202638212 233 download share 25 view s 6 download s article 23 sep 2026 xpr1 promotes the malignant phenotypes of thyroid carcinoma cells partly through nf κb related signaling jie you tongxin zou boxi wang buran chen yefeng cai renyi xiao endong chen dixin xue ming yu discov med 2026 38 212 3016 3027 https doi org 10 24976 discov med 202638212 232 download share 27 view s 11 download s article 23 sep 2026 norepinephrine induces inflammation and injury related changes in epicardial adipose derived cells via the p38 mapk and nf κb signaling pathways and is associated with calcium handling protein changes and cellular injury in h9c2 cells exposed to epicardial adipose derived cell culture media fu li ping chen lina ma yu wang shaojing xi discov med 2026 38 212 3002 3015 https doi org 10 24976 discov med 202638212 231 download share 31 view s 7 download s article 23 sep 2026 ss 31 attenuates lipopolysaccharide induced injury in hk 2 renal tubular epithelial cells via sirt3 mediated regulation of mitochondrial metabolism xiangwei wu menghan shi min sun zhiyong xu hong chen zhiqiang hu jihui ye discov med 2026 38 212 2990 3001 https doi org 10 24976 discov med 202638212 230 download share 26 view s 7 download s article 23 sep 2026 knockdown of chi3l1 attenuates venous intimal hyperplasia by modulating vascular inflammation and oxidative stress via the jnk erk pathway sishi yan ji xu fengliang yao xuebo chen discov med 2026 38 212 2975 2989 https doi org 10 24976 discov med 202638212 229 download share 21 view s 5 download s article 23 sep 2026 quantitative features of neovascularization in fibrotic age related macular degeneration and their associations with visual changes after a single anti vegf therapy xinyue zhu xincan huang yuanyuan gong huixun jia yanlin qu ting shen jieqiong chen minwen zhou qiyu bo ying hu discov med 2026 38 212 2960 2974 https doi org 10 24976 discov med 202638212 228 download share 22 view s 6 download s special issues mitochondrial dysfunction and bioenergetics in cancer and cardiovascular disease alfredo cruz gregorio submission deadline 31 dec 2026 merging cellular mechanisms and translational strategies in chronic disease lei huang submission deadline 31 jan 2027 autoimmunity in rheumatic diseases state of art jozelio f carvalho yehuda shoenfeld leonid churilov submission deadline 28 feb 2027 biomarkers and neuroimmune mechanisms in neurodegeneration and neurological disorders ryszard pluta submission deadline 31 may 2027 about discovery medicine discovery medicine is a peer reviewed academic journal indexed in the science citation index expanded sci e of web of science the journal publishes research in the field of medicine with a particular focus on advancing the understanding of physiological and pathological mechanisms in human health and disease as well as on the development improvement and clinical evaluation of strategies for disease prevention diagnosis and treatment it aims to provide a global platform for researchers and clinicians to disseminate impactful findings and to facilitate the continuous advancement of medical research and clinical practice more about discovery medicine about discovery medicine discovery medicine is a peer reviewed academic journal indexed in the science citation index expanded sci e of web of science the journal publishes research in the field of medicine with a particular focus on advancing the understanding of physiological and pathological mechanisms in human health and disease as well as on the development improvement and clinical evaluation of strategies for disease prevention diagnosis and treatment it aims to provide a global platform for researchers and clinicians to disseminate impactful findings and to facilitate the continuous advancement of medical research and clinical practice more about discovery medicine biomarkers and neuroimmune mechanisms in neurodegeneration and neurological disorders professor liang qiao has joined as associate editor in chief of the discovery medicine 2025 journal impact factor updated editorial system migration notice merging cellular mechanisms and translational strategies in chronic disease implementation of image integrity review tool in discovery medicine what led you to become eic editorial board jun li liu editor in chief gene targeting and transgenic overexpression in mice pancreatic islet growth and protection metabolic regulation and the mechanism of diabetes mellitus anne vejux associate editor in chief oxysterols very long chain fatty acids lipid metabolism peroxisomes biotherapies inflammation cancer cell cycle and apoptosis autophagy biological membranes oxidative damage biomarkers neurodegenerative diseases diet brain liang qiao associate editor in chief liver disease gastrointestinal diseases cancer stem cells pre clinical models organoids experimental cancer therapy fatty liver disease animal models of human diseases diana amantea editorial board member cerebral ischemia neuro immune interactions neuroinflammation neuroprotection stroke announcements editorial system migration notice 15 jun 2026 discovery medicine journal identity and submission information 1 may 2026 highlights review 20 jan 2025 neuroinflammation in the post ischemic brain in the presence of amyloid and tau protein ryszard pluta discov med 2025 37 192 1 18 https doi org 10 24976 discov med 202537192 1 download share 222 view s 100 download s 18 citation s editorial 20 sep 2024 antimicrobial resistance a global public health concern that needs perspective combating strategies and new talented antibiotics abdelazeem mohamed algammal payam behzadi discov med 2024 36 188 1911 1913 https doi org 10 24976 discov med 202436188 177 download share 206 view s 60 download s 51 citation s article 20 feb 2024 thermoresponsive and injectable pluronic f127 hydrogel for loading adipose derived mesenchymal stem cells khan sharun shajahan amitha banu merlin mamachan rony s emmanuel rohit kumar obli rajendran vinodhkumar kuldeep dhama abhijit motiram pawde swapan kumar maiti amar pal discov med 2024 36 181 294 307 https doi org 10 24976 discov med 202436181 28 download share 254 view s 97 download s 22 citation s review 20 feb 2024 growth differentiation factor 15 orchestrates inflammation related diseases via macrophage polarization jingjing huang xinhuan ding yuan dong haiyan zhu discov med 2024 36 181 248 255 https doi org 10 24976 discov med 202436181 23 download share 165 view s 127 download s 23 citation s email alert add your e mail address to receive forthcoming issues of this journal subscribe article list latest issue top read systematic review 23 sep 2026 the era of rapid acting antidepressants clinical insights into ketamine esketamine and scopolamine jozélio freire de carvalho eduardo pondé de sena discov med 2026 38 212 3051 3058 https doi org 10 24976 discov med 202638212 235 download share 77 view s 22 download s article 23 sep 2026 tlr3 overexpression attenuates d galn lps induced acute liver injury and is associated with ampk phosphorylation autophagy related changes and irf3 upregulation yi zhang jun zou xiang chen discov med 2026 38 212 3036 3050 https doi org 10 24976 discov med 202638212 234 download share 34 view s 11 download s article 23 sep 2026 lower limb muscle mass parameters predict short term prognosis after endovascular intervention for non thrombotic iliac vein compression syndrome with varicose veins yanqing zhan chenshu li juan wang peng qiu tingmiao wu zhigang wang hui ma hongji pu jinhua zhou wei chen discov med 2026 38 212 3028 3035 https doi org 10 24976 discov med 202638212 233 download share 25 view s 6 download s article 23 sep 2026 xpr1 promotes the malignant phenotypes of thyroid carcinoma cells partly through nf κb related signaling jie you tongxin zou boxi wang buran chen yefeng cai renyi xiao endong chen dixin xue ming yu discov med 2026 38 212 3016 3027 https doi org 10 24976 discov med 202638212 232 download share 27 view s 11 download s article 23 sep 2026 norepinephrine induces inflammation and injury related changes in epicardial adipose derived cells via the p38 mapk and nf κb signaling pathways and is associated with calcium handling protein changes and cellular injury in h9c2 cells exposed to epicardial adipose derived cell culture media fu li ping chen lina ma yu wang shaojing xi discov med 2026 38 212 3002 3015 https doi org 10 24976 discov med 202638212 231 download share 31 view s 7 download s article 23 sep 2026 ss 31 attenuates lipopolysaccharide induced injury in hk 2 renal tubular epithelial cells via sirt3 mediated regulation of mitochondrial metabolism xiangwei wu menghan shi min sun zhiyong xu hong chen zhiqiang hu jihui ye discov med 2026 38 212 2990 3001 https doi org 10 24976 discov med 202638212 230 download share 26 view s 7 download s article 23 sep 2026 knockdown of chi3l1 attenuates venous intimal hyperplasia by modulating vascular inflammation and oxidative stress via the jnk erk pathway sishi yan ji xu fengliang yao xuebo chen discov med 2026 38 212 2975 2989 https doi org 10 24976 discov med 202638212 229 download share 21 view s 5 download s article 23 sep 2026 quantitative features of neovascularization in fibrotic age related macular degeneration and their associations with visual changes after a single anti vegf therapy xinyue zhu xincan huang yuanyuan gong huixun jia yanlin qu ting shen jieqiong chen minwen zhou qiyu bo ying hu discov med 2026 38 212 2960 2974 https doi org 10 24976 discov med 202638212 228 download share 22 view s 6 download s special issues mitochondrial dysfunction and bioenergetics in cancer and cardiovascular disease alfredo cruz gregorio submission deadline 31 dec 2026 merging cellular mechanisms and translational strategies in chronic disease lei huang submission deadline 31 jan 2027 autoimmunity in rheumatic diseases state of art jozel...