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tic responsible for its rapid onset it is an agonist of the μ opioid receptor while alfentanil tends to cause fewer cardiovascular complications than other similar drugs such as fentanyl and remifentanil it tends to give stronger respiratory depression and so requires careful monitoring of breathing and vital signs almost exclusively used by anesthesia providers during portions of a case where quick fast acting though not long lasting pain control is needed as for example during nerve blocks alfentanil is administered by the parenteral injected route for fast onset and precise control of dosage discovered at janssen pharmaceutica in 1976 alfentanil is classified as a schedule ii drug in the united states 4 history edit the first application of the bolus elimination transfer infusion scheme used alfentanil and etomidate in 1983 5 pharmacology edit alfentanil has moderate binding affinity for the μ opioid receptor in humans at 7 391 nm morphine 1 168 6 references edit anvisa 2023 03 31 rdc nº 784 listas de substâncias entorpecentes psicotrópicas precursoras e outras sob controle especial collegiate board resolution no 784 lists of narcotic psychotropic precursor and other substances under special control in brazilian portuguese diário oficial da união published 2023 04 04 archived from the original on 2023 08 03 retrieved 2023 08 16 shaw leslie m 2001 the clinical toxicology laboratory contemporary practice of poisoning evaluation washington dc aacc press p 89 isbn 978 1 890883 53 9 jacob mathew j kendall killgore methods for the synthesis of alfentanil sufentanil and remifentanil us patent 7 208 604 from dea website accessed 23 jan 2007 archived from the original on 2007 02 02 retrieved 2007 01 23 lamont la creighton cm 11 september 2024 general pharmacology of anesthetic and analgesic drugs in lamont l grimm k robertson s love l schroeder c eds veterinary anesthesia and analgesia the 6th edition of lumb and jones wiley blackwell p 303 isbn 978 1 119 83027 6 simon bt lizarraga i 11 september 2024 opioids in lamont l grimm k robertson s love l schroeder c eds veterinary anesthesia and analgesia the 6th edition of lumb and jones wiley blackwell pp 378 379 isbn 978 1 119 83027 6 external links edit medline plus patient information 09 01 2010 fda gov february 2017 genf interaction table https www hug ch sites interhug files structures pharmacologie_et_toxicologie_cliniques carte_cytochromes_2016_final pdf february 2017 v t e analgesics n02a n02b opioids opiates opium codeine aspirin paracetamol morphine naltrexone opium laudanum paregoric semisynthetic acetyldihydrocodeine benzylmorphine buprenorphine naloxone butorphanol desomorphine dihydrocodeine paracetamol dihydromorphine etorphine ethylmorphine hydrocodone paracetamol ibuprofen aspirin hydromorphinol hydromorphone levorphanol metopon nalbuphine nicocodeine nicodicodine nicomorphine oxycodone paracetamol aspirin ibuprofen naloxone naltrexone oxymorphone papaveretum thebacon synthetic alfentanil alphaprodine anileridine bezitramide carfentanil dextromoramide dextropropoxyphene dezocine dimenoxadol dipipanone ethoheptazine fentanyl fluanisone ketobemidone lofentanil meptazinol methadone nfepp norpipanone oliceridine pentazocine pethidine meperidine phenadoxone phenazocine phenoperidine piminodine piritramide proheptazine propiram remifentanil sufentanil tapentadol tegileridine tilidine tramadol celecoxib paracetamol viminol paracetamol type acetanilide bucetin butacetin paracetamol acetaminophen aspirin caffeine butalbital codeine hydrocodone ibuprofen metoclopramide naproxen oxycodone propyphenazone caffeine tramadol parapropamol phenacetin propacetamol nsaids propionates benoxaprofen fenoprofen flurbiprofen ibuprofen dexibuprofen paracetamol ketoprofen dexketoprofen loxoprofen naproxen paracetamol oxaprozin suprofen tiaprofenic acid zaltoprofen oxicams isoxicam lornoxicam meloxicam piroxicam tenoxicam acetates acemetacin bromfenac diclofenac etodolac indometacin indometacin farnesil ketorolac sulindac tolmetin zomepirac cox 2 inhibitors celecoxib tramadol etoricoxib lumiracoxib parecoxib rofecoxib valdecoxib fenamates flufenamic acid meclofenamic acid mefenamic acid tolfenamic acid salicylates aspirin acetylsalicylic acid paracetamol caffeine aloxiprin benorylate carbasalate calcium choline salicylate diflunisal dipyrocetyl ethenzamide guacetisal imidazole salicylate magnesium salicylate morpholine salicylate potassium salicylate salicin salicylamide salsalate sodium salicylate wintergreen methyl salicylate pyrazolones aminophenazone ampyrone metamizole dipyrone nifenazone phenazone propyphenazone paracetamol caffeine others benzydamine floctafenine glafenine nabumetone nimesulide proquazone cannabinoids cannabidiol cannabis nabilone nabiximols tetrahydrocannabinol dronabinol ion channel modulators calcium blockers alcohol ethanol gabapentin gabapentin enacarbil leconotide mirogabalin pregabalin ziconotide sodium blockers carbamazepine lacosamide local anesthetics e g cocaine lidocaine mexiletine nefopam tricyclic antidepressants e g amitriptyline na v 1 7 1 8 selective dsp 2230 funapide pf 05089771 suzetrigine potassium openers flupirtine myorelaxants carisoprodol chlorzoxazone cyclobenzaprine mephenoxalone methocarbamol orphenadrine others analgecine analgesic adjuvant bedinvetmab camphor capsaicin clonidine frunevetmab hydrocotarnine izenivetmab ketamine menthol methoxyflurane phenazopyridine proglumide relfovetmab rimazolium tanezumab who em withdrawn from market clinical trials phase iii never to phase iii v t e general anesthetics n01a inhalational chloroform cyclopropane desflurane diethyl ether enflurane ethylene fluroxene halothane isoflurane methoxyflurane methoxypropane nitrous oxide sevoflurane trichloroethylene thiomethoxyflurane vinyl ether xenon injection phenols cipepofol ciprofol fospropofol propofol barbiturates amobarbital hexobarbital methohexital narcobarbital thiamylal thiopental thiotetrabarbital benzodiazepines midazolam diazepam lorazepam remimazolam opioids morphine oxycodone anileridine embutramide fentanyl alfentanil phenoperidine remifentanil sufentanil arylcyclohexylamines esketamine ketamine phencyclidine tiletamine neuroactive steroids alfadolone alfaxalone hydroxydione others etomidate propoxate metomidate propanidid who em withdrawn from market clinical trials phase iii never to phase iii v t e opioid receptor modulators μ opioid mor agonists abridged full list 3 ho pcp 7 acetoxymitragynine 7 hydroxymitragynine ψ akuammigine α chlornaltrexamine α narcotine acetyldihydrocodeine acetylfentanyl acrylfentanyl adrenorphin metorphamide ah 7921 akuammicine akuammidine alfentanil anileridine apparicine β endorphin bam 12p bam 18p bam 22p benzhydrocodone benzylmorphine bezitramide biphalin bu08070 buprenorphine butorphan butorphanol butyrfentanyl bw373u86 carfentanil casokefamide cebranopadol chloroxymorphamine codeine dadle damgo dago dermorphin desmetramadol desmethyltramadol desomorphine deumitragynine dextromoramide dextropropoxyphene propoxyphene dezocine dimenoxadol dimethylaminopivalophenone eluxadoline diamorphine heroin dihydrocodeine dihydroetorphine dihydromorphine dinalbuphine sebacate diphenoxylate dipipanone dynorphin a embutramide endomorphin 1 endomorphin 2 eseroline ethylmorphine etorphine fentanyl fluorophen frakefamide furanylfentanyl hemorphin 4 herkinorin hodgkinsine hydrocodone hydromorphinol hydromorphone ibntxa ketamine ketobemidone kratom laudanosine lefetamine leu enkephalin levacetylmethadol levomethorphan levorphanol lexanopadol loperamide loxicodegol ls 115509 matrine meb 1170 meptazinol met enkephalin metenkefalin methadone metkefamide metopon mitragynine mitragynine pseudoindoxyl morphiceptin morphine nalbuphine naloxone benzoylhydrazone nalbzoh nalmexone naltalimide neopine nfepp nicocodeine nicodicodine nicomorphine norketamine nufenoxole octreotide oliceridine oxycodegol nktr 181 oxymorphone 3 methoxynaltrexonazine om 3 mnz oripavine oxycodone oxymorphazone oxymorphonazine oxymorphone oxymorphone phenylhydrazone oxypnph papaver somniferum opium pentazocine pericine pethidine meperidine phenazocine phencyclidine piminodine piritramide pl 017 prodine propiram pzm21 racemethorphan racemorphan remifentanil salsolinol sc 17599 sinomenine sr 15099 sr 17018 sufentanil susineridine tapentadol tetrahydropapaveroline th 030418 thebaine thienorphine tianeptine tilidine tramadol trimebutine trimu 5 trv734 tubotaiwine u 47700 valorphin viminol xorphanol antagonists 3s 4s picenadol 2 s n n r viminol 3cs nalmefene 4 caffeoyl 1 5 quinide 4 hydroxyflavanone 4 7 dihydroxyflavone 6β naltrexol 6β naltrexol d4 18 mc α gliadin β chlornaltrexamine β funaltrexamine akuammine alvimopan am 251 apigenin at 076 axelopran bevenopran catechin catechin gallate clocinnamox ctap ctop cyclofoxy cyprodime diacetylnalorphine diprenorphine ecg egc epicatechin eptazocine gemazocine ginsenoside r hyperoside ibogaine jdtic levallorphan lobeline ly 255582 ly 2196044 methocinnamox methylnaltrexone methylsamidorphan naldemedine nalmefene nalodeine n allylnorcodeine nalorphine nalorphine dinicotinate naloxazone naloxegol naloxol naloxonazine naloxone naltrexazone naltrexonazine naltrexone naltrindole naringenin noribogaine oxilorphan pawhuskin a rimonabant quadazocine samidorphan taxifolin δ opioid dor agonists 3cs nalmefene 6 gnti 7 siom adl 5747 pf 04856881 adl 5859 alazocine skf 10047 amoxapine ar m100390 arm390 azd2327 β endorphin bam 18p biphalin bu 48 butorphan butorphanol bw373u86 casokefamide cebranopadol codeine cyclazocine dadle deltorphin a deltorphin i deltorphin ii desmethylclozapine desmetramadol desmethyltramadol dezocine diamorphine heroin dihydroetorphine dihydromorphine dpdpe dpi 221 dpi 3290 dslet ethylketazocine etorphine fentanyl fit fluorophen hemorphin 4 hydrocodone hydromorphone ibogaine isomethadone jnj 20788560 knt 127 kratom laudanosine leu enkephalin levomethorphan levorphanol lexanopadol lofentanil met enkephalin metenkefalin metazocine metkefamide mitragynine mitragynine pseudoindoxyl morphine n phenethyl 14 ethoxymetopon norbuprenorphine nalbzoh oripavine oxycodone oxymorphone pethidine meperidine proglumide racemethorphan racemorphan rwj 394674 samidorphan sb 235863 snc 80 snc 162 tan 67 sb 205 607 th 030418 thebaine thiobromadol c 8813 tonazocine tramadol trv250 xorphanol zenazocine antagonists 4 7 dihydroxyflavone 5 ntii 6β naltrexol 6β naltrexol d4 α santolol β chlornaltrexamine apigenin at 076 axelopran bevenopran bntx catechin catechin gallate clocinnamox diacetylnalorphine diprenorphine ecg egc eluxadoline epicatechin ici 154129 ici 174864 ly 255582 ly 2196044 methylnaltrexone methylnaltrindole n benzylnaltrindole nalmefene nalorphine naltrexone naltriben naltrindole naloxone naringenin noribogaine pawhuskin a quadazocine sdm25n sori 9409 taxifolin thienorphine κ opioid kor agonists 3cs nalmefene 4 allyl 6 oxa noribogainalog 6 gnti 8 cac 18 mc 14 methoxymetopon β chlornaltrexamine β funaltrexamine adrenorphin metorphamide akuammicine alazocine skf 10047 allomatrine apadoline asimadoline bam 12p bam 18p bam 22p big dynorphin bremazocine brl 52537 butorphan butorphanol bw373u86 cebranopadol ciprefadol cr665 cyclazocine cyclorphan cyprenorphine desmetramadol desmethyltramadol diamorphine heroin diacetylnalorphine difelikefalin dihydroetorphine dihydromorphine dinalbuphine sebacate diprenorphine dynorphin a dynorphin b rimorphin eluxadoline enadoline eptazocine erinacine e ethylketazocine etorphine fedotozine fentanyl gemazocine gr 89696 gr 103545 hemorphin 4 herkinorin hs665 hydromorphone hz 2 ibogaine ici 199 441 ici 204 448 ketamine ketazocine laudanosine leumorphin dynorphin b 29 levallorphan levomethorphan levorphanol lexanopadol lofentanil lpk 26 lufuradom matrine mb 1c oh meb 1170 menthol metazocine metkefamide mianserin mirtazapine morphine moxazocine mr 2034 n mppp nalbuphine nalbzoh nalfurafine nalmefene nalodeine n allylnorcodeine nalorphine naltriben niravoline norbuprenorphine norbuprenorphine 3 glucuronide noribogaine norketamine oripavine oxa noribogaine oxilorphan oxycodone pentazocine pethidine meperidine phenazocine proxorphan racemethorphan racemorphan rb 64 salvinorin a salvia salvinorin b ethoxymethyl ether salvinorin b methoxymethyl ether samidorphan spiradoline u 62066 th 030418 thienorphine tifluadom tricyclic antidepressants e g amitriptyline desipramine imipramine nortriptyline u 50488 u 54494a u 69593 xorphanol antagonists 4 hydroxyflavanone 4 7 dihydroxyflavone 5 gnti 6 gnti 6β naltrexol 6β naltrexol d4 β chlornaltrexamine buprenorphine samidorphan amentoflavone anti apigenin arodyne at 076 aticaprant axelopran az mtab binaltorphimine bu09059 buprenorphine catechin catechin gallate cerc 501 ly 2456302 clocinnamox cvl 354 cyclofoxy dezocine dippa egc ecg epicatechin hyperoside jdtic ly 255582 ly 2196044 ly 2444296 ly 2459989 ly 2795050 mejdtic methylnaltrexone ml190 ml350 mr 2266 n fluoropropyl jdtic naloxone naltrexone naltrindole naringenin navacaprant norbinaltorphimine noribogaine pawhuskin a pf 4455242 rb 64 ru 24213 quadazocine taxifolin uphit zyklophin nociceptin nop agonists arg14 lys15 nociceptin pf phe 4 nociceptin 1 13 nh 2 phe 1 ψ ch 2 nh gly 2 nociceptin 1 13 nh 2 ac ryyrwk nh 2 ac ryyrik nh 2 bu08070 buprenorphine cebranopadol dihydroetorphine etorphine jnj 19385899 levomethorphan levorphanol lexanopadol mcoppb mt 7716 nnc 63 0532 nociceptin orphanin fq nociceptin 1 11 nociceptin 1 13 nh 2 norbuprenorphine racemethorphan racemorphan ro64 6198 ro65 6570 sch 221510 sch 486757 sr 8993 sr 16435 sunobinop s 117957 th 030418 antagonists nphe 1 nociceptin 1 13 nh 2 at 076 ban orl 24 btrx 246040 ly 2940094 j 113397 jtc 801 nalbzoh nociceptin 1 7 nocistatin sb 612111 sr 16430 thienorphine trap 101 ufp 101 others enkephalinase inhibitors amastatin bl 2401 candoxatril d phenylalanine dexecadotril retorphan ecadotril sinorphan kelatorphan racecadotril acetorphan rb 101 rb 120 rb 3007 opiorphan selank semax spinorphin thiorphan tynorphin ubenimex bestatin propeptides β lipotropin proendorphin prodynorphin proenkephalin pronociceptin proopiomelanocortin pomc others kyotorphin met enkephalin releaser degradation stabilizer retrieved from https en wikipedia org w index php title alfentanil oldid 1360846894 categories general anesthetics synthetic opioids piperidines tetrazoles ureas ethers lactams anilides mu opioid receptor agonists janssen pharmaceutica belgian inventions fentanyl hidden categories articles with short description short description is different from wikidata cs1 brazilian portuguese language sources pt br echa infocard id from wikidata this page was last edited on 24 june 2026 at 00 17 utc page was rendered with parsoid text is available under the creative commons attribution sharealike 4 0 license additional terms may apply by using this site you agree to the terms of use and privacy policy wikipedia is a 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