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t waves of plague that twice devastated europe and changed the course of history had their origins in china a team of medical geneticists reported sunday as did a third plague outbreak that struck less harmfully in the 19th century in the issue of nature genetics published online sunday they conclude that all three of the great waves of plague originated from china where the root of their tree is situated the likely origin of the plague in china has nothing to do with its people or crowded cities dr achtman said the bacterium has no interest in people whom it slaughters by accident its natural hosts are various species of rodent such as marmots and voles which are found throughout china morelli et al 2010 eroshenko ga nosov ny krasnov ym oglodin yg kukleva lm guseva np et al 2017 yersinia pestis strains of ancient phylogenetic branch 0 ant are widely spread in the high mountain plague foci of kyrgyzstan plos one 12 10 e0187230 bibcode 2017ploso 1287230e doi 10 1371 journal pone 0187230 pmc 5658180 pmid 29073248 1 2 3 slavin 2019 1 2 spyrou ma tukhbatova ri feldman m drath j kacki s beltrán de heredia j et al june 2016 historical y pestis genomes reveal the european black death as the source of ancient and modern plague pandemics cell host microbe 19 6 874 881 doi 10 1016 j chom 2016 05 012 pmid 27281573 1 2 3 4 moore m 1 november 2010 black death may have originated in china the daily telegraph archived from the original on 18 october 2017 retrieved 2 april 2018 creighton c 1891 a history of epidemics in britain cambridge at the university press p 153 1 2 3 4 5 sussman 2011 kohn gc 2008 encyclopedia of plague and pestilence from ancient times to the present infobase publishing p 31 isbn 978 0 8160 6935 4 archived from the original on 31 march 2019 retrieved 16 october 2015 hecker 1859 p 21 cited by ziegler p 15 1 2 sussman 2011 p 328 benedictow 2004 pp 48 49 benedictow 2004 pp 50 51 von glahn 2016 p 440 green 2020 baker g 1847 1350 gilles aj ed galfridi le baker de 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