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dess martin oxidation wikipedia jump to content main menu main menu move to sidebar hide navigation main page contents current events random article about wikipedia contact us contribute help learn to edit community portal recent changes upload file special pages search search appearance donate create account log in personal tools donate create account log in contents move to sidebar hide top 1 references toggle the table of contents dess martin oxidation 7 languages čeština español فارسی русский தமிழ் ไทย українська edit links article talk english read edit view history tools tools move to sidebar hide actions read edit view history general what links here related changes upload file permanent link page information cite this page get shortened url switch to legacy parser print export download as pdf printable version in other projects wikimedia commons wikidata item appearance move to sidebar hide from wikipedia the free encyclopedia chemical reaction this article is about the oxidation reaction for the oxidizing reagent see dess martin periodinane dess martin oxidation named after daniel benjamin dess james cullen martin reaction type organic redox reaction identifiers organic chemistry portal dess martin oxidation rsc ontology id rxno 0000256 the dess martin oxidation is an organic reaction for the oxidation of primary alcohols to aldehydes and secondary alcohols to ketones using dess martin periodinane 1 2 it is named after the american chemists daniel benjamin dess and james cullen martin who developed the periodinane reagent in 1983 the reaction uses a hypervalent iodine reagent 2 similar to 2 iodoxybenzoic acid to selectively and mildly oxidize alcohols to aldehydes or ketones the reaction is commonly conducted in chlorinated solvents such as dichloromethane or chloroform 2 the reaction can be done at room temperature and is quickly complete many other functional groups will not be affected by this reaction the dess martin oxidation may be preferable to other oxidation reactions as it is very mild avoids the use of toxic chromium reagents does not require large excess or co oxidants and has a relatively easy workup citation needed mechanism of the dess martin oxidation the reaction produces two equivalents of acetic acid it can be buffered with pyridine or sodium bicarbonate in order to protect acid labile compounds the rate of oxidation can be increased by the addition of water to the reaction mixture 3 references edit dess daniel b martin james cullen 1983 readily accessible 12 i 5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones j org chem 48 22 4155 4156 doi 10 1021 jo00170a070 1 2 3 carey francis a sundberg richard j 2007 advanced organic chemistry part b reactions and synthesis 5th ed new york springer p 1072 isbn 978 0387683546 meyer stephanie d schreiber stuart l 1994 acceleration of the dess martin oxidation by water j org chem 59 24 7549 7552 doi 10 1021 jo00103a067 retrieved from https en wikipedia org w index php title dess martin_oxidation oldid 1355957538 categories organic oxidation reactions name reactions hidden categories articles with short description short description matches wikidata all articles with unsourced statements articles with unsourced statements from may 2025 this page was last edited on 24 may 2026 at 22 39 utc page was rendered with parsoid text is available under the creative commons attribution sharealike 4 0 license additional terms may apply by using this site you agree to the terms of use and privacy policy wikipedia is a registered trademark of the wikimedia foundation inc a non profit organization privacy policy about wikipedia disclaimers contact wikipedia legal safety contacts code of conduct developers statistics cookie statement mobile view search search toggle the table of contents dess martin oxidation 7 languages add topic
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