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receptor (50), the (42), colony (36), #stimulating (36), factor (36), granulocyte (34), and (30), pmid (27), doi (27), csf (19), human (18), interferon (17), receptors (14), edit (13), gene (12), with (11), interleukin (11), for (11), epoetin (10), binding (10), see (9), alfa (9), pmc (9), cytokine (8), differentiation (8), blood (8), wikipedia (7), ligand (7), here (7), agonists (7), beta (7), csf3r (7), protein (7), search (6), chromosome (6), instead (6), also (6), signaling (6), expression (6), myeloid (6), 1148 (6), mouse (6), view (5), may (5), this (5), page (5), from (5), leukemia (5), tyrosine (5), kinase (5), ifn (5), erythropoietin (5), 125 (5), national (5), extracellular (5), domain (5), region (5), 1073 (5), pnas (5), proc (5), natl (5), acad (5), sci (5), 1991 (5), that (5), ensembl (5), cell (5), bone (5), membrane (5), contents (4), commons (4), jak (4), family (4), other (4), gcsf (4), medicine (4), external (4), links (4), 1996 (4), identification (4), 1995 (4), 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organization (2), wikimedia (2), use (2), was (2), categories (2), short (2), description (2), different (2), lestaurtinib (2), modulators (2), like (2), others (2), 154 (2), ruxolitinib (2), nsc (2), deuruxolitinib (2), 124 (2), baricitinib (2), jak2 (2), jak1 (2), inhibitors (2), tnf (2), ifnlr (2), peginterferon (2), omega (2), kappa (2), alpha (2), kit (2), 290 (2), chemokine (2), category (2), il12rb1 (2), stat (2), 371 (2), 351 (2), 350 (2), 344 (2), 333 (2), 324 (2), 321 (2), 301 (2), 278 (2), 249 (2), 233 (2), 201 (2), 200 (2), 151 (2), 150 (2), 117 (2), 115 (2), 114 (2), 101 (2), 100 (2), list (2), proteins (2), structure (2), 2d9q (2), 791 (2), res (2), haniu (2), katta (2), 1021 (2), biochemistry (2), layton (2), dimerization (2), 1006 (2), biochem (2), 4683 (2), three (2), lyn (2), 270 (2), 13814 (2), okamura (2), clin (2), functional (2), dong (2), welte (2), hdl (2), med (2), patients (2), 4480 (2), 2985 (2), both (2), 9323 (2), 1559 (2), hematopoietin (2), domains (2), 1016 (2), 8702 (2), 259 (2), anderson (2), cannizzaro (2), steinman (2), croce (2), huebner (2), 1371413 (2), v79 (2), cdnas (2), mapping (2), 1p32 (2), mds (2), s2cid (2), leuk (2), lymphoma (2), further (2), reading (2), ward (2), monkhouse (2), csar (2), hck (2), activated (2), grb2 (2), defective (2), kostmann (2), entrez (2), center (2), biotechnology (2), 2017 (2), release (2), ensmusg00000028859 (2), ensg00000119535 (2), references (2), interactions (2), are (2), significance (2), isoforms (2), transmembrane (2), humans (2), cd114 (2), refseq (2), entry (2), mediated (2), pathway (2), cellular (2), integral (2), more (2), data (2), right (2), spleen (2), expressed (2), lobe (2), ortholog (2), end (2), start (2), band (2), appearance (2), upload (2), file (2), changes (2), history (2), read (2), article (2), log (2), create (2), account (2), donate (2), menu (2), add, topic, mobile, cookie, statement, statistics, developers, code, conduct, legal, safety, contacts, disclaimers, 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il9r, il7ra, il7r, il13ra2, il13ra1, il13r, il4r, il15r, il2rb, il2ra, il2r, tnfrsf27, eda2r, tnfrsf25, dr3, tnfrsf21, dr6, tnfrsf19, taj, troy, tnfrsf18, gitr, tnfrsf17, bcma, tnfrsf16, ngfr, tnfrsf14, hvem, tnfrsf13c, baffr, tnfrsf13b, taci, tnfrsf12a, tweakr, tnfrsf11b, osteoprotegerin, tnfrsf11a, rank, tnfrsf10d, dcr2, tnfrsf10c, dcr1, tnfrsf10b, dr5, tnfrsf10a, dr4, tnfrsf9, tnfrsf8, cd30, tnfrsf7, cd27, tnfrsf6b, dcr3, tnfrsf6, fas, tnfrsf5, cd40, tnfrsf4, tnfrsf3, ltbr, tnfrsf1b, tnfr2, tnfrsf1a, tnfr1, cmklr1, ackr, xcr1, cx3c, cx3cr1, cxcr6, cxcr5, cxcr4, cxcr3, cxcr2, cxcr1, cxc, ccr10, ccr9, ccr8, ccr7, ccr6, ccr5, ccr4, ccr3, ccrl2, ccr2, ccr1, gpcrs, 370, 369, 368, 367, 366, 365, 364, 363, 362, 361, 360, 358, 357, 355, 354, 353, 352, 349, 340, 339, 338, 337, 336, 335, 334, 332, 331, 329, 328, 327, 326, 325, 322, 320, 318, 317, 316, 315, 314, 312, 309, 307, 306, 305, 304, 303, 302, 300a, 299, 298, 297, 295, 294, w293, 292, 289, 288, 286, 284, 283, 282, 281, 280, 279, 276, 275, 274, 273, 272, 271, 269, 268, 267, 266, 265, 264, 263, 262, 261, 258, 257, 256, 254, 253, 252, 300, 248, 247, 246, 244, 243, 241, 240d, 240ce, 239, 238, 236, 235, 234, 230, 229, 228, 227, 226, 225, 224, 223, 222, 221, 220, 218, 217, 213a, 212, w210, 209, 208, 207, 206, 205, 204, 202b, 250, w199, w198, 197, 196, 195, 194, 193, 192, 191, 186, 185, 184, 183, 182, 181, 180, 179, 178, 177, 174, 171, 170, 169, 168, 167, 166, 164, 163, 162, 161, 160, 159, 158, 157, 156, 155, 153, 152, 147, 146, 144, 143, 142, 141, 140b, 138, 137, 136, 135, 134, 133, 132, 131, 130, 129, 127, 126, 123, 122, 121, 120, 119, 118, 116, 113, 112, 111, 110, 109, 108, 107, 106, 105, 104, 103, 102, crystal, gallery, mesh, medical, subject, headings, bonaldo, lennon, soares, 1997, 806, 8889548, 1101, genome, normalization, subtraction, two, approaches, facilitate, discovery, hara, disulfide, glycosylation, sites, 8855939, bi960213u, 13040, mccracken, shorter, starkey, barlow, mardon, regulated, during, development, 8708536, 1677, joe, 1490249, 149, endocrinol, wen, narhi, parker, garcia, granuloycte, monovalent, induces, complexes, 8664280, bi9525841, 4886, rohde, interaction, close, proximity, 8554326, abbi, 0047, arch, corey, burkhardt, bolen, geahlen, tkatch, 8197119, 43852, 4683c, involves, formation, syk, kinases, zhao, wagner, frank, kraft, 7775438, 1074, jbc, biol, chem, amino, terminal, necessary, phosphorylation, shimoda, harada, kondo, niho, 1993, 7682568, 288100, 1172, jci116330, 1310, invest, platelets, brynes, tidow, löwenberg, 7542747, 1765, 60338, 1056, nejm199508243330804, 487, engl, preceded, hoefsloot, schelen, broeders, meijer, veerman, 7514305, 43809, 4480d, nonsense, mutation, nicholson, oates, harpur, ziemiecki, wilks, 7512720, 43499, 2985n, become, phosphorylated, after, activation, uzumaki, okabe, sasaki, hagiwara, takaku, tobita, 1990, 2480598, 298487, characterization, trophoblastic, larsen, davis, curtis, gimpel, sims, cosman, 2147944, 2188748, 1084, jem, exp, structural, mosaic, immunoglobulin, fibronectin, inazawa, nakagawa, misawa, abe, assignment, p35, p34, 1833306, 0888, 7543, 90202, 1075, genomics, ishizaka, ikeda, pan, 1717255, 452996, 1002, 1460, 2075, tb07835, 2855, embo, mizushima, 1701053, 55027, mrnas, encoding, 1530796, 4049, jimmunol, immunol, chromosomal, kimura, sultana, 2005, cd34, myelodysplastic, 2000, 36625508, 15370243, 1080, 10428190410001714034, tsuji, ebihara, progenitors, 8010177, 11911419, 3109, 10428190109097763, 1351, bello, october, src, docks, 9790917, bbrc, 9441, 1998bbrc, 117w, commun, hamilton, november, 9824671, 10536, dro, 30096477, s0167, 4889, 00120, 1448, biochim, acta, direct, shc, shp, p40, murine, ehlers, herbst, zimmermann, scharn, germeshausen, von, neuhoff, 20406937, 1200, jco, 2009, 9010, 2591, oncol, treatment, childhood, leukemias, overexpress, higher, incidence, relapse, beekman, june, 20237318, 234120, 5131, malignancy, zeidler, april, 11957189, 1053, shem, 31913, semin, hematol, mehta, futami, glaubach, lee, andolina, yang, 2014, 1051, 24170028, 5875430, 1038, leu, 2013, 1041, alternatively, spliced, truncated, promotes, leukemogenic, properties, sensitivity, inhibition, march, grcm38, grch38, cluster, has, been, shown, shc1, interact, there, suggestion, should, avoided, least, children, adolescents, perhaps, adults, when, csfr, overexpressed, intracellular, part, certain, types, cause, class, internalization, consists, cytoplasmic, responsible, through, including, erk1, luster, ifferentiation, encoded, surface, belong, present, precursor, stimulation, initiates, into, mature, neutrophilic, macrophages, granulocytes, proliferation, ucsc, np_031808, np_001239580, np_758519, np_724781, np_000751, nm_007782, nm_001252651, nm_172313, nm_156039, nm_156038, nm_000760, mrna, p40223, q99062, uniprot, 12986, 1441, species, oma, ncbi, databases, orthologs, sources, quickgo, amigo, amelogenesis, neutrophil, chemotaxis, regulation, adhesion, defense, biological, process, side, 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Text of the page (random words):
rula stroma of bone marrow spleen mesenteric lymph nodes right lung more reference expression data biogps more reference expression data gene ontology molecular function cytokine receptor activity protein binding granulocyte colony stimulating factor binding signaling receptor activity interleukin 3 receptor activity cytokine binding interleukin 3 binding cellular component integral component of membrane extracellular region integral component of plasma membrane membrane plasma membrane external side of plasma membrane receptor complex biological process defense response cell adhesion regulation of myeloid cell differentiation neutrophil chemotaxis signal transduction amelogenesis cytokine mediated signaling pathway cellular response to interleukin 3 interleukin 3 mediated signaling pathway sources amigo quickgo orthologs databases ncbi entry oma entry species human mouse entrez 1441 12986 ensembl ensg00000119535 ensmusg00000028859 uniprot q99062 p40223 refseq mrna nm_000760 nm_156038 nm_156039 nm_172313 nm_001252651 nm_007782 refseq protein np_000751 np_724781 np_758519 np_001239580 np_031808 location ucsc chr 1 36 47 36 48 mb chr 4 125 92 125 94 mb pubmed search 3 4 wikidata view edit human view edit mouse the granulocyte colony stimulating factor receptor g csf r also known as cd114 c luster of d ifferentiation 114 is a protein that in humans is encoded by the csf3r gene 5 g csf r is a cell surface receptor for the granulocyte colony stimulating factor g csf 6 the g csf receptors belong to a family of cytokine receptors known as the hematopoietin receptor family the granulocyte colony stimulating factor receptor is present on precursor cells in the bone marrow and in response to stimulation by g csf initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages the g csf r is a transmembrane receptor that consists of an extracellular ligand binding portion a transmembrane domain and the cytoplasmic portion that is responsible for signal transduction gcsf r ligand binding is associated with dimerization of the receptor and signal transduction through proteins including jak lyn stat and erk1 2 isoforms edit the class iv isoform defective for both internalization and differentiation signaling 7 and colony stimulating clinical significance edit mutations in this gene are a cause of kostmann syndrome also known as severe congenital neutropenia 8 mutations in the intracellular part of this receptor are also associated with certain types of leukemia 9 in clinical medicine there is a suggestion that use of gcsf should be avoided at least in children and adolescents and perhaps adults when g csfr isoform iv is overexpressed 10 interactions edit granulocyte colony stimulating factor receptor has been shown to interact with grb2 11 hck 12 and shc1 11 see also edit cluster of differentiation references edit 1 2 3 grch38 ensembl release 89 ensg00000119535 ensembl may 2017 1 2 3 grcm38 ensembl release 89 ensmusg00000028859 ensembl may 2017 human pubmed reference national center for biotechnology information u s national library of medicine mouse pubmed reference national center for biotechnology information u s national library of medicine tweardy dj anderson k cannizzaro la steinman ra croce cm huebner k march 1992 molecular cloning of cdnas for the human granulocyte colony stimulating factor receptor from hl 60 and mapping of the gene to chromosome region 1p32 34 blood 79 5 1148 54 doi 10 1182 blood v79 5 1148 1148 pmid 1371413 entrez gene csf3r colony stimulating factor 3 receptor granulocyte mehta hm futami m glaubach t lee dw andolina jr yang q et al may 2014 alternatively spliced truncated gcsf receptor promotes leukemogenic properties and sensitivity to jak inhibition leukemia 28 5 1041 1051 doi 10 1038 leu 2013 321 pmc 5875430 pmid 24170028 zeidler c welte k april 2002 kostmann syndrome and severe congenital neutropenia semin hematol 39 2 82 8 doi 10 1053 shem 2002 31913 pmid 11957189 beekman r touw ip june 2010 g csf and its receptor in myeloid malignancy blood 115 25 5131 6 doi 10 1182 blood 2010 01 234120 pmid 20237318 ehlers s herbst c zimmermann m scharn n germeshausen m von neuhoff n et al may 2010 granulocyte colony stimulating factor g csf treatment of childhood acute myeloid leukemias that overexpress the differentiation defective g csf receptor isoform iv is associated with a higher incidence of relapse j clin oncol 28 15 2591 7 doi 10 1200 jco 2009 25 9010 pmid 20406937 1 2 ward ac monkhouse jl hamilton ja csar xf november 1998 direct binding of shc grb2 shp 2 and p40 to the murine granulocyte colony stimulating factor receptor biochim biophys acta 1448 1 70 6 doi 10 1016 s0167 4889 98 00120 7 hdl 10536 dro du 30096477 pmid 9824671 ward ac monkhouse jl csar xf touw ip bello pa october 1998 the src like tyrosine kinase hck is activated by granulocyte colony stimulating factor g csf and docks to the activated g csf receptor biochem biophys res commun 251 1 117 23 bibcode 1998bbrc 251 117w doi 10 1006 bbrc 1998 9441 pmid 9790917 further reading edit tsuji k ebihara y 2002 expression of g csf receptor on myeloid progenitors leuk lymphoma 42 6 1351 7 doi 10 3109 10428190109097763 pmid 11911419 s2cid 8010177 kimura a sultana ta 2005 granulocyte colony stimulating factor receptors on cd34 cells in patients with myelodysplastic syndrome mds and mds acute myeloid leukemia leuk lymphoma 45 10 1995 2000 doi 10 1080 10428190410001714034 pmid 15370243 s2cid 36625508 tweardy dj anderson k cannizzaro la steinman ra croce cm huebner k 1992 molecular cloning of cdnas for the human granulocyte colony stimulating factor receptor from hl 60 and mapping of the gene to chromosome region 1p32 34 blood 79 5 1148 54 doi 10 1182 blood v79 5 1148 1148 pmid 1371413 seto y fukunaga r nagata s 1992 chromosomal gene organization of the human granulocyte colony stimulating factor receptor j immunol 148 1 259 66 doi 10 4049 jimmunol 148 1 259 pmid 1530796 fukunaga r seto y mizushima s nagata s 1991 three different mrnas encoding human granulocyte colony stimulating factor receptor proc natl acad sci u s a 87 22 8702 6 doi 10 1073 pnas 87 22 8702 pmc 55027 pmid 1701053 fukunaga r ishizaka ikeda e pan cx seto y nagata s 1991 functional domains of the granulocyte colony stimulating factor receptor embo j 10 10 2855 65 doi 10 1002 j 1460 2075 1991 tb07835 x pmc 452996 pmid 1717255 inazawa j fukunaga r seto y nakagawa h misawa s abe t et al 1991 assignment of the human granulocyte colony stimulating factor receptor gene csf3r to chromosome 1 at region p35 p34 3 genomics 10 4 1075 8 doi 10 1016 0888 7543 91 90202 p pmid 1833306 larsen a davis t curtis bm gimpel s sims je cosman d et al 1991 expression cloning of a human granulocyte colony stimulating factor receptor a structural mosaic of hematopoietin receptor immunoglobulin and fibronectin domains j exp med 172 6 1559 70 doi 10 1084 jem 172 6 1559 pmc 2188748 pmid 2147944 uzumaki h okabe t sasaki n hagiwara k takaku f tobita m et al 1990 identification and characterization of receptors for granulocyte colony stimulating factor on human placenta and trophoblastic cells proc natl acad sci u s a 86 23 9323 6 doi 10 1073 pnas 86 23 9323 pmc 298487 pmid 2480598 nicholson se oates ac harpur ag ziemiecki a wilks af layton je 1994 tyrosine kinase jak1 is associated with the granulocyte colony stimulating factor receptor and both become tyrosine phosphorylated after receptor activation proc natl acad sci u s a 91 8 2985 8 bibcode 1994pnas 91 2985n doi 10 1073 pnas 91 8 2985 pmc 43499 pmid 7512720 dong f hoefsloot lh schelen am broeders ca meijer y veerman aj et al 1994 identification of a nonsense mutation in the granulocyte colony stimulating factor receptor in severe congenital neutropenia proc natl acad sci u s a 91 10 4480 4 bibcode 1994pnas 91 4480d doi 10 1073 pnas 91 10 4480 pmc 43809 pmid 7514305 dong f brynes rk tidow n welte k löwenberg b touw ip 1995 mutations in the gene for the granulocyte colony stimulating factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia n engl j med 333 8 487 93 doi 10 1056 nejm199508243330804 hdl 1765 60338 pmid 7542747 shimoda k okamura s harada n kondo s okamura t niho y 1993 identification of a functional receptor for granulocyte colony stimulating factor on platelets j clin invest 91 4 1310 3 doi 10 1172 jci116330 pmc 288100 pmid 7682568 zhao y wagner f frank sj kraft as 1995 the amino terminal portion of the jak2 protein kinase is necessary for binding and phosphorylation of the granulocyte macrophage colony stimulating factor receptor beta c chain j biol chem 270 23 13814 8 doi 10 1074 jbc 270 23 13814 pmid 7775438 corey sj burkhardt al bolen jb geahlen rl tkatch ls tweardy dj 1994 granulocyte colony stimulating factor receptor signaling involves the formation of a three component complex with lyn and syk protein tyrosine kinases proc natl acad sci u s a 91 11 4683 7 bibcode 1994pnas 91 4683c doi 10 1073 pnas 91 11 4683 pmc 43852 pmid 8197119 haniu m horan t arakawa t le j katta v rohde mf 1996 extracellular domain of granulocyte colony stimulating factor receptor interaction with its ligand and identification of a domain in close proximity of ligand binding region arch biochem biophys 324 2 344 56 doi 10 1006 abbi 1995 0047 pmid 8554326 horan t wen j narhi l parker v garcia a arakawa t et al 1996 dimerization of the extracellular domain of granuloycte colony stimulating factor receptor by ligand binding a monovalent ligand induces 2 2 complexes biochemistry 35 15 4886 96 doi 10 1021 bi9525841 pmid 8664280 mccracken s layton je shorter sc starkey pm barlow dh mardon hj 1996 expression of granulocyte colony stimulating factor and its receptor is regulated during the development of the human placenta j endocrinol 149 2 249 58 doi 10 1677 joe 0 1490249 pmid 8708536 haniu m horan t arakawa t le j katta v hara s et al 1996 disulfide structure and n glycosylation sites of an extracellular domain of granulocyte colony stimulating factor receptor biochemistry 35 40 13040 6 doi 10 1021 bi960213u pmid 8855939 bonaldo mf lennon g soares mb 1997 normalization and subtraction two approaches to facilitate gene discovery genome res 6 9 791 806 doi 10 1101 gr 6 9 791 pmid 8889548 external links edit csf3r protein human at the u s national library of medicine medical subject headings mesh v t e pdb gallery 2d9q crystal structure of the human gcsf receptor signaling complex v t e proteins clusters of differentiation see also list of human clusters of differentiation 1 50 1 a c 1a 1b 1d 1e 2 3 γ δ ε 4 5 6 7 8 a 9 10 11 a b c d 13 14 15 16 a b 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 a b 33 34 35 36 37 38 39 40 41 42 a b c d 43 44 45 46 47 48 49 a b c d e f 50 51 100 51 52 53 54 55 56 57 58 59 61 62 e l p 63 64 a b c 66 a b c d e f 68 69 70 71 72 73 74 78 79 a b 80 81 82 83 84 85 a d e h j k 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 150 101 102 103 104 105 106 107 a b 108 109 110 111 112 113 114 115 116 117 118 119 120 a b 121 a b 122 123 124 125 126 127 129 130 131 132 133 134 135 136 137 138 140b 141 142 143 144 146 147 148 150 151 200 151 152 153 154 155 156 a b c 157 158 a d e i k 159 a c 160 161 162 163 164 166 167 a b 168 169 170 171 172 a b g 174 177 178 179 a b 180 181 182 183 184 185 186 191 192 193 194 195 196 197 w198 w199 200 201 250 201 202b 204 205 206 207 208 209 w210 a b 212 213a 1 2 217 218 a b 220 221 222 223 224 225 226 227 228 229 230 233 234 235 a b 236 238 239 240ce 240d 241 243 244 246 247 248 249 251 300 252 253 254 256 257 258 261 262 263 264 265 266 267 268 269 271 272 273 274 275 276 278 279 280 281 282 283 284 286 288 289 290 292 w293 294 295 297 298 299 301 350 300a 301 302 303 304 305 306 307 309 312 314 315 316 317 318 320 321 322 324 325 326 327 328 329 331 332 333 334 335 336 337 338 339 340 344 349 350 351 371 351 352 353 354 355 357 358 360 361 362 363 364 365 366 367 368 369 370 371 category commons v t e cytokine receptors chemokine receptor gpcrs cc ccr1 ccr2 ccrl2 ccr3 ccr4 ccr5 ccr6 ccr7 ccr8 ccr9 ccr10 cxc cxcr1 cxcr2 cxcr3 cxcr4 cxcr5 cxcr6 other cx3c cx3cr1 xc xcr1 ackr 1 2 3 4 5 cmklr1 tnf receptor 1 10 tnfr1 tnfrsf1a tnfr2 tnfrsf1b ltbr tnfrsf3 tnfrsf4 cd40 tnfrsf5 fas receptor tnfrsf6 dcr3 tnfrsf6b cd27 tnfrsf7 cd30 tnfrsf8 tnfrsf9 11 20 dr4 tnfrsf10a dr5 tnfrsf10b dcr1 tnfrsf10c dcr2 tnfrsf10d rank tnfrsf11a osteoprotegerin tnfrsf11b tweakr tnfrsf12a taci tnfrsf13b baffr tnfrsf13c hvem tnfrsf14 ngfr tnfrsf16 bcma tnfrsf17 gitr tnfrsf18 taj troy tnfrsf19 21 27 dr6 tnfrsf21 dr3 tnfrsf25 eda2r tnfrsf27 jak stat type i γ chain interleukin receptors il2r il2ra il2rb il15r il4r il13r il13ra1 il13ra2 il7r il7ra il9r il21r β chain interleukin receptors il3r il3ra il5r il5ra gm csf gp130 interleukin receptors il6ra 11 il11ra 27 il27ra osmr lifr cntfr il12rb1 interleukin receptors il12r il12rb1 il12rb2 il23r other other csf receptors epo g csf thrombopoietin hormone receptor gh prolactin type ii interleukin receptors il10r il10ra il10rb il22r il22ra1 il22ra2 il20r il20ra il20rb il28r interferon receptors α β ifnar1 ifnar2 γ ifngr1 ifngr2 ig superfamily il1 il1r1 il1r2 il18r il18r1 il 17 family il17 il17ra il17rb il17rc il17rd il17re enzyme linked receptor tyr csf1r kit ser thr tgf beta tgfbr1 tgfbr2 family category commons v t e cytokine receptor modulators chemokine see here instead csf erythropoietin agonists ara 290 asialo erythropoietin carbamylated erythropoietin cnto 530 darbepoetin alfa epoetin alfa epoetin beta epoetin delta epoetin epsilon epoetin gamma epoetin kappa epoetin omega epoetin theta epoetin zeta erythropoietin epo erythropoietin fc methoxy polyethylene glycol epoetin beta cera mircera peginesatide pegol sihematide epo 018b g csf csf3 agonists filgrastim granulocyte colony stimulating factor lenograstim leridistim lipegfilgrastim nartograstim pegfilgrastim pegnartograstim gm csf csf2 agonists ecogramostim granulocyte macrophage colony stimulating factor milodistim molgramostim regramostim sargramostim antibodies mavrilimumab namilumab otilimab m csf csf1 agonists cilmostim interleukin 34 lanimostim macrophage colony stimulating factor mirimostim kinase inhibitors agerafenib scf c kit see here instead thrombopoietin agonists eltrombopag pegacaristim promegapoietin romiplostim avatrombopag lusutrombopag thrombopoietin thpo mgdf interferon ifnar α β i agonists albinterferon interferon alpha interferon alfa ifn α interferon alfa ifna1 ifna2 ifna4 ifna5 ifna6 ifna7 ifna8 ifna10 ifna13 ifna14 ifna16 ifna17 ifna21 interferon alfa 2a interferon alfa 2b interferon alfa n1 interferon alfacon 1 interferon alpha n3 interferon beta ifn β ifnb1 ifnb3 interferon beta 1a interferon beta 1b interferon kappa ifn ε κ τ ζ ifnk interferon omega ifn ω ifnw1 peginterferon alfa 2a peginterferon alfa 2b antibodies anifrolumab faralimomab medi 545 rontalizumab sifalimumab decoy receptors bifarcept ifngr γ ii agonists interferon gamma ifn γ interfero...
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