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hylactic antibiotics are not utilized 13 in patients with diabetes quality foot care may prevent development of om 13 epidemiology edit about 2 4 per 100 000 people are affected by osteomyelitis each year 6 the young and old are more commonly affected 8 1 males are more commonly affected than females 3 history edit the word is from greek words ὀστέον osteon meaning bone μυελός myelos meaning marrow and ῖτις itis meaning inflammation in 1875 american artist thomas eakins depicted a surgical procedure for osteomyelitis at jefferson medical college in an oil painting titled the gross clinic 48 canadian politician and premier of saskatchewan tommy douglas suffered from osteomyelitis as a child and in 1910 underwent several surgeries which the surgeon performed for free in exchange for allowing his medical students to observe the procedures which douglas s parents could not have otherwise afforded this experience convinced him that medical care should be free for everyone 49 douglas became known as the canadian father of medicare 50 before the widespread availability and use of antibiotics blow fly larvae were sometimes deliberately introduced to the wounds to feed on the infected material effectively scouring them clean 51 52 ancient dna analysis of pre antibiotic era 19th 20th century human bone specimens from germany recovered staphylococcus aureus streptococcus pyogenes and acinetobacter baumannii genomes showing that many virulence genes and antimicrobial resistance genes seen in modern strains were already present before antibiotics came into use with some strains belonging to lineages responsible for outbreaks worldwide today 53 fossil record edit main article paleopathology evidence for osteomyelitis found in the fossil record is studied by paleopathologists specialists in ancient disease and injury it has been reported in fossils of the large carnivorous dinosaur allosaurus fragilis 54 osteomyelitis has been also associated with the first evidence of parasites in dinosaur bones 55 see also edit brodie abscess chronic recurrent multifocal osteomyelitis sapho syndrome garre s sclerosing osteomyelitis references edit 1 2 3 4 5 6 osteomyelitis nord national organization for rare disorders 2005 archived from the original on 11 february 2017 retrieved 20 july 2017 1 2 3 4 5 osteomyelitis genetic and rare diseases information center gard 2016 archived from the original on 9 february 2017 retrieved 20 july 2017 1 2 ferri fred f 2017 ferri s clinical advisor 2018 e book 5 books in 1 elsevier health sciences p 924 isbn 978 0 323 52957 0 archived from the original on 2017 09 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 schmitt sk june 2017 osteomyelitis infectious disease clinics of north america 31 2 325 38 doi 10 1016 j idc 2017 01 010 pmid 28483044 s2cid 257184257 bennett john e dolin raphael blaser martin j 2014 principles and practice of infectious diseases elsevier health sciences p 2267 isbn 978 1 4557 4801 3 archived from the original on 2017 09 10 1 2 hochberg marc c silman alan j smolen josef s et al 2014 rheumatology e book elsevier health sciences p 885 isbn 978 0 7020 6303 9 archived from the original on 2017 09 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 bury david c rogers tyler s dickman michael m 2021 osteomyelitis diagnosis and treatment american family physician 104 4 395 402 issn 1532 0650 pmid 34652112 archived from the original on 2025 09 15 1 2 3 4 5 el sobky t mahmoud s july 2021 acute osteoarticular infections in children are frequently forgotten multidiscipline emergencies beyond the technical skills efort open reviews 6 7 584 592 doi 10 1302 2058 5241 6 200155 pmc 8335954 pmid 34377550 1 2 3 osteomyelitis genetic and rare diseases information center gard 2016 archived from the original on 9 february 2017 retrieved 20 july 2017 el sobky ta haleem jf samir s 2015 eumycetoma osteomyelitis of the calcaneus in a child a radiologic pathologic correlation following total calcanectomy case reports in pathology 2015 129020 doi 10 1155 2015 129020 pmc 4592886 pmid 26483983 1 2 colston julia atkins bridget march 18 2018 bone and joint infection clinical medicine 18 2 150 154 doi 10 7861 clinmedicine 18 2 150 pmc 6303448 pmid 29626020 brackenridge r d c croxson richard s mackenzie ross 2016 medical selection of life risks 5th edition swiss re branded springer p 912 isbn 978 1 349 56632 7 archived from the original on 2017 09 10 1 2 3 4 5 6 7 8 9 10 11 12 13 chin hong peter joyce elizabeth a karandikar manjiree matloubian mehrdad rubio luis alberto schwartz brian levinson warren 2024 70 bone joint infections levinson s review of medical microbiology immunology a guide to clinical infectious diseases 18th ed access medicine mcgraw hill isbn 978 1 265 12600 1 el sobky t mahmoud s july 2021 acute osteoarticular infections in children are frequently forgotten multidiscipline emergencies beyond the technical skills efort open reviews 6 7 584 592 doi 10 1302 2058 5241 6 200155 pmc 8335954 pmid 34377550 1 2 3 4 5 6 7 kumar vinay abbas abul k fausto nelson mitchell richard n 2007 robbins basic pathology 8th ed saunders elsevier pp 810 11 isbn 978 1 4160 2973 1 carek p j l m dickerson j l sack 2001 06 15 diagnosis and management of osteomyelitis am fam physician 63 12 2413 20 pmid 11430456 burnett m w j w bass b a cook 1998 02 01 etiology of osteomyelitis complicating sickle cell disease pediatrics 101 2 296 97 doi 10 1542 peds 101 2 296 pmid 9445507 osteomyelitis mayo clinic 8 november 2022 retrieved 25 july 2023 berbari elie f kanj souha s kowalski todd j darouiche rabih o widmer andreas f schmitt steven k hendershot edward f holtom paul d huddleston paul m petermann gregory w osmon douglas r 2015 09 15 2015 infectious diseases society of america idsa clinical practice guidelines for the diagnosis and treatment of native vertebral osteomyelitis in adultsa clinical infectious diseases 61 6 e26 e46 doi 10 1093 cid civ482 issn 1537 6591 pmid 26229122 weinstein lenny knowlton christin a smith miriam a 2007 12 16 cervical osteomyelitis caused by burkholderia cepacia after rhinoplasty journal of infection in developing countries 2 1 76 77 doi 10 3855 jidc 327 issn 1972 2680 pmid 19736393 1 2 3 4 yang ze lin bingyuan ren haiyong liu yiyang huang kai guo qiaofeng wang xiang august 1 2025 risk factors for osteomyelitis a systematic review and meta analysis international journal of surgery 111 8 5606 5622 doi 10 1097 js9 0000000000002811 issn 1743 9159 pmid 40607967 1 2 luqmani raashid robb james daniel porter benjamin joseph 2013 orthopaedics trauma and rheumatology 2nd ed mosby p 96 isbn 978 0 7234 3680 5 king md randall w johnson d 2006 07 13 osteomyelitis emedicine webmd archived from the original on 2007 11 09 retrieved 2007 11 11 1 2 3 4 5 kumar vinay abbas abul k aster jon c deyrup andrea t 2023 bones joints and soft tissue tumors robbins kumar basic pathology 11th ed elsevier isbn 978 0 323 79018 5 ellington jk reilly ss 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complex regional pain syndrome hypertrophic pulmonary osteoarthropathy nonossifying fibroma pseudarthrosis stress fracture fibrous dysplasia monostotic polyostotic skeletal fluorosis bone cyst aneurysmal bone cyst hyperostosis infantile cortical hyperostosis osteosclerosis melorheostosis pycnodysostosis joint chondritis costochondritis relapsing polychondritis other slipping rib syndrome tietze syndrome combined osteochondritis osteochondritis dissecans child leg hip legg calvé perthes disease tibia osgood schlatter disease blount s disease foot köhler disease sever s disease spine scheuermann s disease arm wrist kienböck s disease elbow panner disease authority control databases international gnd national united states france bnf data czech republic israel other yale lux retrieved from https en wikipedia org w index php title osteomyelitis oldid 1375985238 categories bacterial diseases osteopathies hidden categories articles with short description short description is different from wikidata comm...