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siglec9 wikipedia jump to content main menu main menu move to sidebar hide navigation main page contents current events random article about wikipedia contact us contribute help learn to edit community portal recent changes upload file special pages search search appearance donate create account log in personal tools donate create account log in contents move to sidebar hide top 1 references 2 further reading toggle the table of contents siglec9 4 languages العربية مصرى татарча tatarça українська edit links article talk english read edit view history tools tools move to sidebar hide actions read edit view history general what links here related changes upload file permanent link page information cite this page get shortened url switch to legacy parser print export download as pdf printable version in other projects wikidata item appearance move to sidebar hide from wikipedia the free encyclopedia protein coding gene in the species homo sapiens siglec9 identifiers aliases siglec9 cd329 cdw329 foap 9 obbp like siglec 9 sialic acid binding ig like lectin 9 external ids omim 605640 mgi 1932475 genecards siglec9 gene location human chr chromosome 19 human 1 band 19q13 41 start 51 124 906 bp 1 end 51 136 651 bp 1 gene location mouse chr chromosome 7 mouse 2 band 7 b3 7 start 43 300 494 bp 2 end 43 309 585 bp 2 rna expression pattern bgee human mouse ortholog top expressed in monocyte granulocyte blood spleen upper lobe of left lung gonad right adrenal cortex appendix right lung left adrenal gland top expressed in granulocyte zygote secondary oocyte spleen blood embryo embryo right kidney bone marrow primary oocyte more reference expression data biogps more reference expression data gene ontology molecular function carbohydrate binding protein binding cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane secretory granule membrane biological process cell surface receptor signaling pathway cell adhesion regulation of immune response neutrophil degranulation sources amigo quickgo orthologs databases ncbi entry oma entry species human mouse entrez 27180 83382 ensembl ensg00000129450 ensmusg00000030474 uniprot q9y336 q91y57 refseq mrna nm_001198558 nm_014441 nm_031181 refseq protein np_001185487 np_055256 np_112458 location ucsc chr 19 51 12 51 14 mb chr 7 43 3 43 31 mb pubmed search 3 4 wikidata view edit human view edit mouse sialic acid binding ig like lectin 9 is a protein that in humans is encoded by the siglec9 gene 5 6 references edit 1 2 3 grch38 ensembl release 89 ensg00000129450 ensembl may 2017 1 2 3 grcm38 ensembl release 89 ensmusg00000030474 ensembl may 2017 human pubmed reference national center for biotechnology information u s national library of medicine mouse pubmed reference national center for biotechnology information u s national library of medicine foussias g yousef gm diamandis ep aug 2000 identification and molecular characterization of a novel member of the siglec family siglec9 genomics 67 2 171 8 doi 10 1006 geno 2000 6208 pmid 10903842 entrez gene siglec9 sialic acid binding ig like lectin 9 further reading edit yousef gm luo ly diamandis ep 2000 identification of novel human kallikrein like genes on chromosome 19q13 3 q13 4 anticancer res 19 4b 2843 52 pmid 10652563 angata t varki a 2000 cloning characterization and phylogenetic analysis of siglec 9 a new member of the cd33 related group of siglecs evidence for co evolution with sialic acid synthesis pathways j biol chem 275 29 22127 35 doi 10 1074 jbc m002775200 pmid 10801860 zhang jq nicoll g jones c crocker pr 2000 siglec 9 a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes j biol chem 275 29 22121 6 doi 10 1074 jbc m002788200 pmid 10801862 strausberg rl feingold ea grouse lh et al 2003 generation and initial analysis of more than 15 000 full length human and mouse cdna sequences proc natl acad sci u s a 99 26 16899 903 bibcode 2002pnas 9916899m doi 10 1073 pnas 242603899 pmc 139241 pmid 12477932 clark hf gurney al abaya e et al 2003 the secreted protein discovery initiative spdi a large scale effort to identify novel human secreted and transmembrane proteins a bioinformatics assessment genome res 13 10 2265 70 doi 10 1101 gr 1293003 pmc 403697 pmid 12975309 sonnenburg jl altheide tk varki a 2004 a uniquely human consequence of domain specific functional adaptation in a sialic acid binding receptor glycobiology 14 4 339 46 doi 10 1093 glycob cwh039 pmid 14693915 grimwood j gordon la olsen a et al 2004 the dna sequence and biology of human chromosome 19 nature 428 6982 529 35 bibcode 2004natur 428 529g doi 10 1038 nature02399 pmid 15057824 ikehara y ikehara sk paulson jc 2004 negative regulation of t cell receptor signaling by siglec 7 p70 airm and siglec 9 j biol chem 279 41 43117 25 doi 10 1074 jbc m403538200 pmid 15292262 avril t floyd h lopez f et al 2005 the membrane proximal immunoreceptor tyrosine based inhibitory motif is critical for the inhibitory signaling mediated by siglecs 7 and 9 cd33 related siglecs expressed on human monocytes and nk cells j immunol 173 11 6841 9 doi 10 4049 jimmunol 173 11 6841 pmid 15557178 von gunten s yousefi s seitz m et al 2005 siglec 9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment blood 106 4 1423 31 doi 10 1182 blood 2004 10 4112 pmid 15827126 rapoport em pazynina gv sablina ma et al 2006 probing sialic acid binding ig like lectins siglecs with sulfated oligosaccharides biochemistry mosc 71 5 496 504 doi 10 1134 s0006297906050051 pmid 16732727 s2cid 11537303 biedermann b gil d bowen dt crocker pr 2007 analysis of the cd33 related siglec family reveals that siglec 9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors leuk res 31 2 211 20 doi 10 1016 j leukres 2006 05 026 pmid 16828866 v t e protein lectins animal c type lectins asialoglycoprotein receptor klrd1 collectin mannan binding lectin mannose receptor proteochondroitin sulfate aggrecan versican brevican neurocan siglec sialoadhesin cd22 cd33 myelin associated glycoprotein siglec5 siglec6 siglec7 siglec8 siglec9 siglec10 siglec12 other calnexin calreticulin galectin n acetylglucosamine receptor selectin plant toxalbumins abrin ricin mitogens concanavalin a phytohaemagglutinin pokeweed mitogen legume lectin banlec v t e proteins clusters of differentiation see also list of human clusters of differentiation 1 50 1 a c 1a 1b 1d 1e 2 3 γ δ ε 4 5 6 7 8 a 9 10 11 a b c d 13 14 15 16 a b 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 a b 33 34 35 36 37 38 39 40 41 42 a b c d 43 44 45 46 47 48 49 a b c d e f 50 51 100 51 52 53 54 55 56 57 58 59 61 62 e l p 63 64 a b c 66 a b c d e f 68 69 70 71 72 73 74 78 79 a b 80 81 82 83 84 85 a d e h j k 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 150 101 102 103 104 105 106 107 a b 108 109 110 111 112 113 114 115 116 117 118 119 120 a b 121 a b 122 123 124 125 126 127 129 130 131 132 133 134 135 136 137 138 140b 141 142 143 144 146 147 148 150 151 200 151 152 153 154 155 156 a b c 157 158 a d e i k 159 a c 160 161 162 163 164 166 167 a b 168 169 170 171 172 a b g 174 177 178 179 a b 180 181 182 183 184 185 186 191 192 193 194 195 196 197 w198 w199 200 201 250 201 202b 204 205 206 207 208 209 w210 a b 212 213a 1 2 217 218 a b 220 221 222 223 224 225 226 227 228 229 230 233 234 235 a b 236 238 239 240ce 240d 241 243 244 246 247 248 249 251 300 252 253 254 256 257 258 261 262 263 264 265 266 267 268 269 271 272 273 274 275 276 278 279 280 281 282 283 284 286 288 289 290 292 w293 294 295 297 298 299 301 350 300a 301 302 303 304 305 306 307 309 312 314 315 316 317 318 320 321 322 324 325 326 327 328 329 331 332 333 334 335 336 337 338 339 340 344 349 350 351 371 351 352 353 354 355 357 358 360 361 362 363 364 365 366 367 368 369 370 371 category commons this article on a gene on human chromosome 19 is a stub you can help wikipedia by adding missing information v t e retrieved from https en wikipedia org w index php title siglec9 oldid 1300576888 categories genes on human chromosome 19 human chromosome 19 gene stubs hidden categories articles with short description short description matches wikidata all stub articles this page was last edited on 15 july 2025 at 04 45 utc page was rendered with parsoid text is available under the creative commons attribution sharealike 4 0 license additional terms may apply by using this site you agree to the terms of use and privacy policy wikipedia is a registered trademark of the wikimedia foundation inc a non profit organization privacy policy about wikipedia disclaimers contact wikipedia legal safety contacts code of conduct developers statistics cookie statement mobile view search search toggle the table of contents siglec9 4 languages add topic