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moderately, antagonizes, 289, 1351673, 1600, 0773, tb00473, 286, caille, souich, spenard, lacasse, vezina, 1984, parameters, simultaneously, 125, 6743780, bdd, 2510050205, 117, biopharmaceutics, arnestad, karinen, hilberg, woman, bronchogenic, carcinoma, 1249, 11569575, jfs15131j, 1247, harry, 735, 9183949, 731, revue, praticien, carlsten, waern, allebeck, 228, 24102880, 12850977, 14034940210167966, 224, scandinavian, public, dart, lippincott, williams, wilkins, 889, 978, 7817, 2845, isbn, auriculo, ventricular, 380, 2814922, 379, 2353332, pounder, davies, tissue, diffusion, 183, 8039775, 90273, 177, cienki, burkhart, donovan, philadelphia, 41701825, 16235515, 1081, clt, 200058944, 385, responsive, boniface, russell, 133, 8868406, yamazaki, terada, mitsukuni, yoshimura, autopsy, neuropsychopharmaceuticals, 252, 9893443, 245, hoigaku, bocxlaer, clauwaert, lambert, piette, leenheer, 8837952, specimens, hplc, diode, array, meatherall, hospitalized, patient, 343, 9068198, jfs14125j, 340, connell, 1995, 221, 7866122, 2548618, toxicity, mcmanus, ferguson, implications, prescribers, aust, press, mannaert, tytgat, daenens, connected, uncommon, drowning, 8939015, 02018, noguchi, kitazumi, mori, shiba, 15037809, 1254, jphs, electroencephalographic, kanno, watanabe, kazamatsuri, levomepromazine, transient, polygraphic, 239, 54285586, 8430216, 0278, 5846, 90044, 229, neuro, kim, zhuang, tsutsumi, okabe, kurachi, kamikawa, 661, 8290860, comparison, quantitative, women, wright, belyavin, borland, nicholson, 3505734, middle, aged
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harmacokinetics retrieved 5 december 2015 1 2 3 4 victorri vigneau c gérardin m rousselet m guerlais m grall bronnec m jolliet p 2014 an update on zolpidem abuse and dependence journal of addictive diseases 33 1 15 23 doi 10 1080 10550887 2014 882725 pmid 24467433 1 2 3 4 riemann d espie ca altena e arnardottir es baglioni c bassetti cl et al december 2023 the european insomnia guideline an update on the diagnosis and treatment of insomnia 2023 journal of sleep research 32 6 e14035 doi 10 1111 jsr 14035 hdl 11250 3121742 pmid 38016484 1 2 långtidsbehandling med imovane in swedish svelic 2018 retrieved 2026 07 07 1 2 3 4 sateia mj buysse dj krystal ad neubauer dn heald jl february 2017 clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults an american academy of sleep medicine clinical practice guideline journal of clinical sleep medicine jcsm official publication of the american academy of sleep medicine 13 2 307 349 doi 10 5664 jcsm 6470 pmc 5263087 pmid 27998379 1 2 edinoff an wu n ghaffar yt prejean r gremillion r cogburn m et al 2021 zolpidem efficacy and side effects for insomnia health psychology research 9 1 24927 doi 10 52965 001c 24927 pmc 8567759 pmid 34746488 1 2 chapter 3 the technologies section 3 4 clinical need and practice guidance on the use of zaleplon zolpidem and zopiclone for the short term management of insomnia national institute for health and care excellence nice 28 april 2004 technology appraisal guidance ta77 1 2 van der kleijn e 1989 effects of zopiclone and temazepam on sleep behaviour and mood during the day european journal of clinical pharmacology 36 3 247 251 doi 10 1007 bf00558155 issn 0031 6970 pmid 2744064 1 2 3 kuitunen t mattila mj seppala t april 1990 actions and interactions of hypnotics on human performance single doses of zopiclone triazolam and alcohol international clinical psychopharmacology 5 suppl 2 115 130 pmid 2201724 zopiclone consumer information from drugs com retrieved 2013 06 06 administration de justice do april 2005 schedules of controlled substances placement of zopiclone into schedule iv final rule federal register 70 63 16935 16937 pmid 15806735 what s wrong with prescribing hypnotics drug and therapeutics bulletin 42 12 89 93 december 2004 doi 10 1136 dtb 2004 421289 pmid 15587763 s2cid 40188442 touitou y july 2007 sleep disorders and hypnotic agents medical social and economical impact annales pharmaceutiques francaises in french 65 4 230 238 doi 10 1016 s0003 4509 07 90041 3 pmid 17652991 liira j verbeek jh costa g driscoll tr sallinen m isotalo lk et al august 2014 pharmacological interventions for sleepiness and sleep disturbances caused by shift work the cochrane database of systematic reviews 2014 8 cd009776 doi 10 1002 14651858 cd009776 pub2 pmc 10025070 pmid 25113164 cognitive therapy superior to zopiclone for insomnia the journal of family practice 55 10 845 october 2006 pmid 17089469 baillargeon l landreville p verreault r beauchemin jp grégoire jp morin cm november 2003 discontinuation of benzodiazepines among older insomniac adults treated with cognitive behavioural therapy combined with gradual tapering a randomized trial cmaj 169 10 1015 1020 pmc 236226 pmid 14609970 sivertsen b omvik s pallesen s bjorvatn b havik oe kvale g et al june 2006 cognitive behavioral therapy vs zopiclone for treatment of chronic primary insomnia in older adults a randomized controlled trial jama 295 24 2851 2858 doi 10 1001 jama 295 24 2851 pmid 16804151 morgan k dixon s mathers n thompson j tomeny m february 2004 psychological treatment for insomnia in the regulation of long term hypnotic drug use health technology assessment 8 8 winchester england iii iv 1 68 doi 10 3310 hta8080 pmid 14960254 dündar y dodd s strobl j boland a dickson r walley t july 2004 comparative efficacy of newer hypnotic drugs for the short term management of insomnia a systematic review and meta analysis human psychopharmacology 19 5 305 322 doi 10 1002 hup 594 pmid 15252823 s2cid 10888200 mets ma volkerts er olivier b verster jc august 2010 effect of hypnotic drugs on body balance and standing steadiness sleep medicine reviews 14 4 259 267 doi 10 1016 j smrv 2009 10 008 pmid 20171127 tada k sato y sakai t ueda n kasamo k kojima t 1994 effects of zopiclone triazolam and nitrazepam on standing steadiness neuropsychobiology 29 1 17 22 doi 10 1159 000119057 pmid 8127419 allain h bentué ferrer d tarral a gandon jm july 2003 effects on postural oscillation and memory functions of a single dose of zolpidem 5 mg zopiclone 3 75 mg and lormetazepam 1 mg in elderly healthy subjects a randomized cross over double blind study versus placebo european journal of clinical pharmacology 59 3 179 188 doi 10 1007 s00228 003 0591 5 pmid 12756510 s2cid 13440208 antai otong d august 2006 the art of prescribing risks and benefits of non benzodiazepine receptor agonists in the treatment of acute primary insomnia in older adults perspectives in psychiatric care 42 3 196 200 doi 10 1111 j 1744 6163 2006 00070 x pmid 16916422 bain kt june 2006 management of chronic insomnia in elderly persons the american journal of geriatric pharmacotherapy 4 2 168 192 doi 10 1016 j amjopharm 2006 06 006 pmid 16860264 parker g roberts cj september 1983 plasma concentrations and central nervous system effects of the new hypnotic agent zopiclone in patients with chronic liver disease british journal of clinical pharmacology 16 3 259 265 doi 10 1111 j 1365 2125 1983 tb02159 x pmc 1428012 pmid 6626417 kripke df february 2016 mortality risk of hypnotics strengths and limits of evidence pdf drug safety 39 2 93 107 doi 10 1007 s40264 015 0362 0 pmid 26563222 s2cid 7946506 zopiclone british national formulary national institute for health and care excellence 19 september 2016 archived from the original on 9 october 2016 staner l ertlé s boeijinga p rinaudo g arnal ma muzet a et al october 2005 next day residual effects of hypnotics in dsm iv primary insomnia a driving simulator study with simultaneous electroencephalogram monitoring psychopharmacology 181 4 berl 790 798 doi 10 1007 s00213 005 0082 8 pmid 16025317 s2cid 26351598 barbone f mcmahon ad davey pg morris ad reid ic mcdevitt dg et al october 1998 association of road traffic accidents with benzodiazepine use lancet 352 9137 london england 1331 1336 doi 10 1016 s0140 6736 98 04087 2 pmid 9802269 s2cid 40825194 yasui m kato a kanemasa t murata s nishitomi k koike k et al june 2005 pharmacological profiles of benzodiazepinergic hypnotics and correlations with receptor subtypes nihon shinkei seishin yakurigaku zasshi japanese journal of psychopharmacology 25 3 143 151 pmid 16045197 rettig hc de haan p zuurmond ww von leeuwen l december 1990 effects of hypnotics on sleep and psychomotor performance a double blind randomised study of lormetazepam midazolam and zopiclone anaesthesia 45 12 1079 1082 doi 10 1111 j 1365 2044 1990 tb14896 x pmid 2278337 s2cid 36841164 lader m denney sc 1982 a double blind study to establish the residual effects of zopiclone on performance in healthy volunteers international pharmacopsychiatry 17 suppl 2 98 108 pmid 7188379 billiard m besset a de lustrac c brissaud l 1987 dose response effects of zopiclone on night sleep and on nighttime and daytime functioning sleep 10 suppl 1 27 34 doi 10 1093 sleep 10 suppl_1 27 pmid 3326113 paul ma gray g kenny g pigeau ra december 2003 impact of melatonin zaleplon zopiclone and temazepam on psychomotor performance aviation space and environmental medicine 74 12 aerospace medical association 1263 1270 pmid 14692469 trachsel l dijk dj brunner dp klene c borbély aa february 1990 effect of zopiclone and midazolam on sleep and eeg spectra in a phase advanced sleep schedule neuropsychopharmacology 3 1 11 18 pmid 2306331 mann k bauer h hiemke c röschke j wetzel h benkert o august 1996 acute subchronic and discontinuation effects of zopiclone on sleep eeg and nocturnal melatonin secretion european neuropsychopharmacology 6 3 163 168 doi 10 1016 0924 977x 96 00014 4 pmid 8880074 s2cid 25259646 wright na belyavin a borland rg nicholson an june 1986 modulation of delta activity by hypnotics in middle aged subjects studies with a benzodiazepine flurazepam and a cyclopyrrolone zopiclone sleep 9 2 348 352 doi 10 1093 sleep 9 2 348 pmid 3505734 kim yd zhuang hy tsutsumi m okabe a kurachi m kamikawa y october 1993 comparison of the effect of zopiclone and brotizolam on sleep eeg by quantitative evaluation in healthy young women sleep 16 7 655 661 doi 10 1093 sleep 16 7 655 pmid 8290860 kanno o watanabe h kazamatsuri h march 1993 effects of zopiclone flunitrazepam triazolam and levomepromazine on the transient change in sleep wake schedule polygraphic study and the evaluation of sleep and daytime condition progress in neuro psychopharmacology biological psychiatry 17 2 229 239 doi 10 1016 0278 5846 93 90044 s pmid 8430216 s2cid 54285586 noguchi h kitazumi k mori m shiba t march 2004 electroencephalographic properties of zaleplon a non benzodiazepine sedative hypnotic in rats journal of pharmacological sciences 94 3 246 251 doi 10 1254 jphs 94 246 pmid 15037809 mannaert e tytgat j daenens p november 1996 detection and quantification of the hypnotic zopiclone connected with an uncommon case of drowning forensic science international 83 1 67 72 doi 10 1016 0379 0738 96 02018 x pmid 8939015 buckley na dawson ah whyte im mcmanus p ferguson n correlations between prescriptions and drugs taken in self poisoning implications for prescribers and drug regulation med j aust in press buckley na dawson ah whyte im o connell dl january 1995 relative toxicity of benzodiazepines in overdose bmj 310 6974 219 221 doi 10 1136 bmj 310 6974 219 pmc 2548618 pmid 7866122 meatherall rc march 1997 zopiclone fatality in a hospitalized patient journal of forensic sciences 42 2 340 343 doi 10 1520 jfs14125j pmid 9068198 van bocxlaer j meyer e clauwaert k lambert w piette m de leenheer a 1996 analysis of zopiclone imovane in postmortem specimens by gc ms and hplc with diode array detection journal of analytical toxicology 20 1 52 54 doi 10 1093 jat 20 1 52 pmid 8837952 yamazaki m terada m mitsukuni y yoshimura m august 1998 an autopsy case of poisoning by neuropsychopharmaceuticals including zopiclone nihon hoigaku zasshi the japanese journal of legal medicine in japanese 52 4 245 252 pmid 9893443 boniface pj russell sg 1996 two cases of fatal zopiclone overdose journal of analytical toxicology 20 2 131 133 doi 10 1093 jat 20 2 131 pmid 8868406 cienki jj burkhart kk donovan jw 2005 zopiclone overdose responsive to flumazenil clinical toxicology 43 5 philadelphia pa 385 386 doi 10 1081 clt 200058944 pmid 16235515 s2cid 41701825 pounder dj davies ji may 1994 zopiclone poisoning tissue distribution and potential for postmortem diffusion forensic science international 65 3 177 183 doi 10 1016 0379 0738 94 90273 9 pmid 8039775 regouby y delomez g tisserant a 1990 first degree heart block caused by voluntary zopiclone poisoning therapie in french 45 2 162 pmid 2353332 regouby y delomez g tisserant a 1989 auriculo ventricular block during voluntary poisoning with zopiclone therapie in french 44 5 379 380 pmid 2814922 dart rc 2003 medical toxicology lippincott williams wilkins p 889 isbn 978 0 7817 2845 4 carlsten a waern m holmgren p allebeck p 2003 the role of benzodiazepines in elderly suicides scandinavian journal of public health 31 3 224 228 doi 10 1080 14034940210167966 pmid 12850977 s2cid 24102880 harry p april 1997 acute poisoning by new psychotropic drugs la revue du praticien 47 7 731 735 pmid 9183949 bramness jg arnestad m karinen r hilberg t september 2001 fatal overdose of zopiclone in an elderly woman with bronchogenic carcinoma journal of forensic sciences 46 5 1247 1249 doi 10 1520 jfs15131j pmid 11569575 caille g du souich p spenard j lacasse y vezina m april 1984 pharmacokinetic and clinical parameters of zopiclone and trimipramine when administered simultaneously to volunteers biopharmaceutics drug disposition 5 2 117 125 doi 10 1002 bdd 2510050205 pmid 6743780 mattila me mattila mj nuotto e april 1992 caffeine moderately antagonizes the effects of triazolam and zopiclone on the psychomotor performance of healthy subjects pharmacology toxicology 70 4 286 289 doi 10 1111 j 1600 0773 1992 tb00473 x pmid 1351673 koski a ojanperä i vuori e may 2003 interaction of alcohol and drugs in fatal poisonings human experimental toxicology 22 5 281 287 bibcode 2003hetox 22 281k doi 10 1191 0960327103ht324oa pmid 12774892 s2cid 37777007 aranko k luurila h backman jt neuvonen pj olkkola kt october 1994 the effect of erythromycin on the pharmacokinetics and pharmacodynamics of zopiclone british journal of clinical pharmacology 38 4 363 367 doi 10 1111 j 1365 2125 1994 tb04367 x pmc 1364781 pmid 7833227 jalava km olkkola kt neuvonen pj 1996 effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone european journal of clinical pharmacology 51 3 4 331 334 doi 10 1007 s002280050207 pmid 9010708 s2cid 20916689 villikka k kivistö kt lamberg ts kantola t neuvonen pj may 1997 concentrations and effects of zopiclone are greatly reduced by rifampicin british journal of clinical pharmacology 43 5 471 474 doi 10 1046 j 1365 2125 1997 00579 x pmc 2042775 pmid 9159561 becquemont l mouajjah s escaffre o beaune p funck brentano c jaillon p september 1999 cytochrome p 450 3a4 and 2c8 are involved in zopiclone metabolism drug metabolism and disposition 27 9 1068 1073 doi 10 1016 s0090 9556 24 15027 1 pmid 10460808 archived from the original on 2005 04 17 retrieved 2008 12 16 alderman cp gebauer mg gilbert al condon jt november 2001 possible interaction of zopiclone and nefazodone the annals of pharmacotherapy 35 11 1378 1380 doi 10 1345 aph 1a074 pmid 11724087 s2cid 38894701 permanent dead link röschke j mann k aldenhoff jb benkert o march 1994 functional properties of the brain during sleep under subchronic zopiclone administration in man european neuropsychopharmacology 4 1 21 30 doi 10 1016 0924 977x 94 90311 5 pmid 8204993 s2cid 40503805 petroski re pomeroy je das r bowman h yang w chen ap et al april 2006 indiplon is a high affinity positive allosteric modulator with selectivity for alpha1 subunit containing gabaa receptors the journal of pharmacology and experimental therapeutics 317 1 369 377 doi 10 1124 jpet 105 096701 pmid 16399882 s2cid 46510829 atack jr august 2003 anxioselective compounds acting at the gaba a receptor benzodiazepine binding site current drug targets cns and neurological disorders 2 4 213 232 doi 10 2174 1568007033482841 pmid 12871032 liu hj sato k shih hc shibuya t kawamoto h kitagawa h march 1985 pharmacologic studies of the central action of zopiclone effects on locomotor activity and brain monoamines in rats international journal of clinical pharmacology therapy and toxicology 23 3 121 128 pmid 2581904 sato k hong yl yang ms shibuya t kawamoto h kitagawa h april 1985 pharmacologic studies of centra...
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