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entactogens com the chemistry of the soul entactogens literally to touch within offer a whole new mode of introspective well being they belie the worry that the happiness of our emotionally enriched descendants will be shallow for the happiness of post darwinian superminds won t be soma like and one dimensional á la aldous huxley s brave new world on the contrary their spectrum of mental superhealth promises to be rich profound and unimaginably diverse contemporary states of depersonalisation and derealisation are typically associated with dysfunction of the serotonin neurotransmitter system by contrast drugs like mdma ecstasy can induce in hugely exaggerated form the opposite of this syndrome by triggering the release of a lot of extra oxytocin serotonin and dopamine and thereby causing post synaptic intra cellular cascades we still don t fully understand the entactogens deliver an enhanced sense of self and reality a greater sense of authenticity and a wonderful i m alive on the planet sense of this is the real me better still the heightened awareness of selfhood one enjoys on mdma and its congeners is very different from the hard edged egotism promoted by dopaminergic power drugs like cocaine and the amphetamines today perhaps most of us feel relatively self alienated we often feel out of touch with ourselves certainly by comparison to what will be normal for our succcessors this self alienation is not properly corrected by psychic anaesthetisers such as prozac this is because the selective serotonin reuptake inhibitors ssris tend to flatten rather than intensify emotion what s needed instead are analogues and enhancements of today s entactogens and empathogens full blown mental health demands the development of designer drugs that are safe clean and sustainable i e act via long term receptor re regulation and altered gene expression profiles rather than explosive monoamine release germ line gene therapy can follow culminating in one scenario at least in genetically preprogrmmed well being for all sentient life by offering at once a clearer sense of self spiritually enriched emotion more lucid introspection and unprecedented self love fused with a profound love of others this extraordinary family of feeling enhancing compounds opens up beautiful new modes of introspection and selfhood although chemically catalysed such new modes of existence don t feel weird so one doesn t feel drugged today we think of feelings of un reality as having a neurophysiological basis but equally one s fluctuating sense of how real things seem is itself chemically based reality does not admit of degrees yet our sense of reality certainly does this sense can be chemically manipulated too thus the psyche can be redesigned so that all our states of consciousness feel more compellingly real than anything accessible to contemporary homo sapiens abstract the molecular biology of paradise 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 mdma hedweb herbweb bltc research sensualism com empathogens com the good drug guide utopian pharmacology quora answers 2015 23 the hedonistic imperative mdma ecstasy research critique of brave new world