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description=The IUPHAR/BPS Guide to PHARMACOLOGY. An expert-driven guide to pharmacological targets with quantitative information on the prescription medicines and experimental drugs that act on them. Developed as a joint initiative of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS) and is now the new home of the IUPHAR Database (IUPHAR-DB).;

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home iuphar bps guide to pharmacology home about about the guide to pharmacology about nc iuphar database content contributors sponsors citing linking to us disclaimer commercial access fees privacy and cookie policy targets gpcrs ion channels lgics vgics other channels nuclear receptors kinases catalytic receptors transporters enzymes other protein targets target search target search tools blast ligands ligand list ligand families ligand search diseases resources help tutorial faq terms and symbols nomenclature guidelines publications antibacterials drug approvals downloads download data and reports web services slides and posters news immunopharmacology meeting 2018 latest news hot topics latest pairings concise guide to pharmacology useful links advanced search target search target search tools blast ligand search pharmacology search immuno portal malaria portal gtopdb now requires users to register to use the website please see our blog post for more information quick links targets g protein coupled receptors ion channels nuclear hormone receptors kinases catalytic receptors transporters enzymes other protein targets ligands approved drugs synthetic organics metabolites natural products endogenous peptides other peptides inorganics antibodies labelled ligands resources help documentation faq tutorial download data reports antibacterials drug approvals rest api web services database reports view all our past database reports on our downloads page reports are also accessible along with database update presentations on our zenodo archive latest report doi 10 5281 zenodo 23667960 advanced search targets target pharmacology ligands chemical structure current release version 2026 3 1 12th october 2026 read our release notes blog coronavirus covid 19 view our information page ligand activity charts use our interactive ligand activity charts to compare pharmacology across targets and species nar database issue the guide to pharmacology in 2026 our latest update in nar database issue has been published and is available online includes developments in antibacterial natural product and nucleic acid based ligand curation and an improved presentation of approved drugs immunopharmacology iuphar guide to immunopharmacology an immunological access point to gtopdb data malaria pharmacology iuphar mmv guide to malaria pharmacology optimised access for the malaria research community latest news and hot topics in pharmacology powered by surfing waves all news our blog hot topics latest pairings the concise guide to pharmacology 2025 26 access the table of contents please see the 5 minute introductory video on the concise guide sorry this content is unavailable until you click to accept cookies from this site accept cookies recent publications insight into structural properties of viral g protein coupled receptors and their role in the viral infection iuphar review 41 tsutsumi n kildedal df hansen ok kong q schols d van loy t rosenkilde mm 2024 br j pharmacol epub ahead of print 10 1111 bph 17379 targeting rna with small molecules from rna structures to precision medicines iuphar review 40 tong y childs disney jl disney md 2024 br j pharmacol epub ahead of print doi 10 1111 bph 17308 advancing the field of viroporins structure function and pharmacology iuphar review 39 devantier k kjær vms griffin s kragelund bb rosenkilde mm 2024 br j pharmacol epub ahead of print 10 1111 bph 17317 international union of basic and clinical pharmacology cxxii applying an objective evaluation to the status of class a orphan g protein coupled receptors alexander sph et al 2026 pharmacol rev 78 4 100141 doi 10 1016 j pharmr 2026 100141 international union of basic and clinical pharmacology cxxi apelin receptor pharmacology in the human cardiovascular system and emerging clinical applications davenport ap williams tl nyimanu d macrae rgc kuc re chapman fa yang p dhaun n maguire jj 2026 pharmacol rev 78 3 100130 doi 10 1016 j pharmr 2026 100130 international union of basic and clinical pharmacology cxx γ hydroxybutyrate protein targets in the mammalian brain beyond classic receptors wellendorph p gauger sj andersen jv kornum br solbak smo frølund b 2025 pharmacol rev 77 4 100064 doi 10 1016 j pharmr 2025 100064 publication list iuphar bps guide to pharmacology citing and license the guide to pharmacology database is licensed under the open data commons open database license odbl its contents are licensed under a creative commons attribution sharealike 4 0 international license in order to cite the database in general please use the following to cite specific data please see our citing page harding sd armstrong jf faccenda e southan c alexander sph davenport ap spedding m davies ja 2025 the iuphar bps guide to pharmacology in 2026 nucl acids res 2026 54 d1 d1446 d1456 doi 10 1093 nar gkaf1067 full text pmid 41160876 download citation vancouver harvard bibtex ris download file contact us privacy and cookie policy sponsors list this work is licensed under a creative commons attribution sharealike 4 0 international license