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kira homepage science pipeline pipeline kp104 about us investors presentations science pipeline pipeline kp104 about us investors presentations pioneering a world free from complement disease explore our mission advancing transformative therapies for patients with complement mediated diseases advancing transformative therapies for patients with complement mediated diseases named after a patient with complement 3 glomerulopathy c3g kira pharmaceuticals is driven by the opportunity for impact with the mission to advance transformative therapies for patients around the world with complement mediated diseases kira pharmaceuticals is a clinical stage biotechnology company pioneering a world free from complement disease enabled by its logic platform the company has developed a robust pipeline of nine 9 novel complement assets since its inception in 2017 focused on validated targets across the complement cascade with an experienced team of complement biology experts drug developers protein engineers and leaders from across the pharma and biotech industry kira pharmaceuticals is uniquely positioned to tackle some of the most complex and toughest challenges in the complement space and to deliver first in class and best in class therapies to transform the lives of patients the challenge complexities of complement the complement systems regulates important immune functions but its complex biology has historically posed a challenge for drug development the complement system is complex and implicated in a large number of autoimmune and inflammatory conditions across hematology nephrology neurology dermatology ophthalmology and many other disease areas however given the complex biology and abundance of proteins involved in the complement system it has historically been challenging to develop effective and convenient therapies to modulate the complement system the science our solution world renowned expertise and logic based approach deep complement knowledge combined with precise drug design and associated validation tools optimize assets for clinical success founded and advised by world renowned complement biology experts and in collaboration with or op tier research institutions both in the us and europe through ongoing sponsored research agreements kira pharmaceuticals is leveraging its proprietary logic platform l ead identification o ptimization and attribute g eneration i n vivo c onfirmation to overcome key challenges of developing complement therapeutics and increasing their probability of success in the clinic we are moving from complexity to clarity to improve the lives of patients anti complement drugs have great potential in treating a variety of human immunological disorders and kira s approach of bringing together deep complement expertise with seasoned and experienced drug developers and protein engineers is a powerful combination to develop next generation therapeutics that could transform the lives of patients with complement mediated disease wenru song md phd president head of r d co founder more on our science and logic approach our pipeline kira pharmaceuticals is pioneering the field developing a broad pipeline of compelling therapies designed to achieve better longer acting and targeted immune modulation across a range of complement diseases with our lead asset entering phase 2 and nine assets in the pipeline we are advancing the next generation of complement therapies these assets are investigational agents and have not yet been approved by any health authority such as the fda assets indications trials vision see our pipeline about our team kira s experienced team includes established drug developers and protein engineers world renowned experts in complement biology and leaders from across the pharma and biotech industry the team is augmented by well respected academic collaborators at major us and european research institutions alongside an outstanding scientific advisory board with international reputations in complement biology and immunology about us kira where established drug developers and world renown experts in complement biology come together to pioneer a world free from complement disease latest news stay up to date with kira pharmaceutical s latest news and updates kira to present at the 41st annual j p morgan healthcare conference cambridge ma january 5 2023 kira pharmaceuticals a global biotechnology jan 05 2023 read full article news kira pharmaceuticals kira pharmaceuticals announces clearance to initiate phase 2 evaluation of kp104 in iga nephropathy igan and complement 3 glomerulopathy c3g in china and australia cambridge ma usa and suzhou jiangsu china december 20 2022 kira dec 20 2022 read full article news kira pharmaceuticals kira pharmaceuticals announces first cohort of patients dosed in phase 2 study of kp104 in paroxysmal nocturnal hemoglobinuria pnh cambridge ma november 30 2022 kira pharmaceuticals a global nov 30 2022 read full article all news presentations see our latest presentations and posters poster synergy 1 a phase 1 first in human safety tolerability immunogenicity pk and pd study of kp104 in escalating single and multiple doses in healthy subjects nov 05 2022 poster emchd 2022 design and characterization of kp104 a bifunctional anti c5 mab and fh1 5 fusion protein that synergistically inhibits alternative and terminal pathways of complement activation aug 26 2022 all presentations latest news stay up to date with kira pharmaceutical s latest news and updates july 16 2026 jasper therapeutics announces merger with kira pharmaceuticals read full news release presentations see our latest presentations and posters presentation corporate presentation july 2026 july 16 2026 poster ash 2025 kp104 a bifunctional c5 mab factor h fusion protein demonstrates sustained long term efficacy and safety in complement inhibitor naïve pnh patients 2 year results from a phase 2 study with 8 week post treatment safety follow up nov 03 2025 all presentations science pipeline about us investors presentations kira pharmaceuticals us llc 245 main street 12th fl cambridge ma 02142 info kirapharma com investors and media argot partners 212 600 1902 kira argotpartners com financial conflict of interest policy terms of use privacy policy 2026 kira pharma company all rights reserved