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ochre bio skip to content why how what who more why how what who more human data human models human translation ochre s platform provides gsk with foundational data to create ai models allowing us to better understand liver function and disease for the development of novel medicines kim branson svp global head of ai and machine learning gsk ochre brings unique and exciting capabilities in liver disease research with the potential to uncover novel pathways that will make a meaningful difference in the lives of those affected by chronic liver disease søren tullin phd svp global head of cardiometabolic diseases research boehringer ingelheim deals like those between ochre and gsk demonstrate how high quality disease specific datasets are becoming as valuable as discovery ip underpinning next generation causal and foundational models andrew marshall phd former chief editor nature biotechnology the future of chronic liver disease treatment is being shaped by ochre bio built by some of the best scientific talent on a foundation of transdisciplinary excellence dr chinwe ukomadu senior vice president and head gastrointestinal and inflammation therapeutic area unit takeda ochre bio board observer ochre is one of several new companies using the latest ai to develop drugs more quickly but the oxford startup is focused squarely on chronic liver disease testing rna therapies for the deadly illness with limited treatments top 25 european startups to watch bloomberg founders forum the scale of ochre s work is uniquely powered to address the complexities of liver disease scott friedman md chief division of liver diseases icahn school of medicine at mount sinai the company is founded on a fully differentiated scientific strategy to uncover and validate fundamental disease pathways in the liver eliot forster phd chair ochre bio ochre s work combining ai with human data to discover rna therapeutics could radically change the future of liver disease medicine and is exciting for the pharma industry elaine sullivan phd senior non executive director ochre bio the company is developing a novel strategy that has potential to positively impact all patients with liver diseases the opportunity to validate targets in actual human livers is something no other company is doing chas bountra obe phd pro vice chancellor for innovation oxford university why we exist ochre exists to end the need for liver transplants 1 5m people globally die of liver disease for the vast majority of these the only curative treatment option is a liver transplant with just over 40k transplants done globally annually it s a medical lottery this is what ochre exists to change european health for all database data missing in 2000 liver disease is the third leading cause of premature death uk health security agency july 2021 how we do things differently human discovery platform we ve invested over 20m to build the most comprehensive human liver data sets by integrating proprietary gene perturbation atlases with patient disease atlases we make causal predictions about new drug targets human validation platform by combining ai with human validation models such as perfused livers diseased tissue slices and primary cells we model biological complexity at scale rna platform we make our own rna therapies in house reducing r d cycle times from years to weeks we believe having a strong rna modality focus improves our chances of clinical success what we re doing pipeline mechanism indication discovery validation lead development development candidate selection ind enabling studies clinical internal partnerships mechanism cytoprotection indication significant fibrosis development candidate ob 220 internal partnerships internal mechanism metabolic indication cirrhosis f4 mash lead development internal partnerships internal mechanism multiple indication significant fibrosis discovery validation internal partnerships internal mechanism regeneration indication cirrhosis discovery validation internal partnerships partnership who we are built on decades of leading genomics ai drug discovery and development experience ochre bio s teams are our secret sauce built on a foundation of ambitious science exec and board no lab nyc organ lab oxford bioescalator oxford oxford science park oxford chem lab oxford dry lab oxford wet lab taipei tissue lab quin wills founder ceo ahmad bashir barekzai clinical research scientist alex k shalek sab member ana miar cuervo lead discovery innovation anthony beucher lead computational biology ashley hoffland scientist i birbal prasad senior scientist i calum irwin scientist i chas bountra sab member chinwe ukomadu board observer cho chin cheng senior scientist i eduardo martins sab member edward o neill scientist i elaine sullivan board member eliot forster board chair esther arnaiz gonzalez scientist ii fabio sanna head of discovery innovation fleur palmer paquis scientist i francesca flintoft burt lead senior programme management giuseppe d agostino principal scientist i guillaume noell principal scientist i jack castle chief business officer jan traulsen scientist i jian hua wang research associate ii jie yu liu lead early validation joanne soong lab manager julian maller head of computational biology jung an lin research associate i kayla lawrence research associate ii kelly tompeck lead perfusion research quin wills founder ceo chinwe ukomadu board observer elaine sullivan board member eliot forster board chair jack castle chief business officer ness bermingham board member sarah batey chief operating officer more latest from linkedin loading linkedin posts oops something went wrong while fetching our awesome linkedin posts mind giving it another try news announcements view all gsk signs ai pact with ochre to pinpoint source of liver diseases june 12 2024 uk biotech signs 1bn deal to develop liver disease drugs april 22 2024 boehringer ingelheim inks chronic liver disease research pact with ochre bio april 22 2024 view all partners investors ochre ideas view all think you d like to join our team check out our open positions or ask us to hold your cv at jobs ochre bio com subscribe for updates more linkedin careers news contact locations oxford uk taipei city taiwan new york city ny contact contact ochre bio com 2026 ochre bio all rights reserved all regular disclaimers apply privacy policy join our mailing list this website uses cookies to ensure you get the best experience on our website view our policy here got it home news careers contact us login facebook f twitter