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description= Quiver Bioscience was built to create transformational medicines for patients living with disorders of the brain. Utilizing human disease models, novel AI, and best-in-world platform, we stand as the premier partner in the journey from target discovery to the clinic.;
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quiver bioscience home our mission platform models signals insights insights pipeline people press join us decoding neurons to unlock breakthrough cns therapeutics mission to accelerate discovery of empirically grounded ai driven therapeutics that deliver transformative value to patients with neurological disease all powered through quiver s innovation engine and strategic partnerships the opportunity brain health is a growing global crisis but neurological drug development continues to see the lowest success rates most failures trace back to weak targets unexpected toxicities and misaligned patient selection issues driven by the historical lack of scalable human relevant models reliable neural measurements and the computational power needed to decode complex brain biology quiver s solution our value proposition is simple safer more effective cns drugs discovered faster and at lower cost with human relevance built in from day one our approach integrates cutting edge scalable biology state of the art technology and engineering and learning and surrogate models to identify novel therapeutic targets and the best candidate molecules to deliver new and meaningful therapeutics to patients 01 models patient derived stem cell models enhance translatability by capturing disease phenotypes in vitro assays are complemented by ex vivo tissue slice assays to probe 3d circuits learn more 02 signals all optical electrophysiology that scalably assesses neuron function at the gold standard resolution but with 10 000x throughput 9 6b action potentials from 126m neurons and counting learn more 03 insights ai models mine our high dimensional data to a establish disease phenotypes b assess drug efficacy c match drugs to targets and d avoid unwanted off vector toxicity learn more quiver s solution our value proposition is simple safer more effective cns drugs discovered faster and at lower cost with human relevance built in from day one our approach integrates cutting edge scalable biology state of the art technology and engineering and learning and surrogate models to identify novel therapeutic targets and the best candidate molecules to deliver new and meaningful therapeutics to patients 01 models patient derived stem cell models enhance translatability by capturing disease phenotypes 02 signals all optical electrophysiology that scalably assesses neuron function at the gold standard resolution but with 5 000x throughput 1b action potentials from 25m neurons in 6 months 03 insights ai models mine our high dimensional data to a establish disease phenotypes b assess drug efficacy c match drugs to targets and d avoid unwanted off vector toxicity our platform powered therapeutic pipeline development stage partner platform value delivered target modality indication discovery pre clinical clinical wholly owned identify the best molecule efficacy toxicity genetically validated nav1 7 aso chronic pain dc in 1q 26 ube3a aso dup15q syndrome dc in 2q 26 nav1 8 aso chronic pain stxbp1 aso dee4 syngap1 aso dee nav1 7 1 8 dual aso chronic pain fmr1 undisclosed fxs identify target and the best molecule novel tsc2 small molecule tsc wholly owned new target discovery undisclosed pharma 1 new target discovery undisclosed pharma 2 dee developmental and epileptic encephalopathy fragile x syndrome tuberous sclerosis excitatory inhibitory additional early discovery programs not listed include scn8a aso dual nav1 7 1 8 aso nav1 8 sm signed in q4 2025 we welcome partnership opportunities with other organizations seeking to develop novel therapeutics for serious diseases or with parties interested in leveraging our unique platform capabilities get in touch press view all may 4 2026 quiver bioscience receives nih heal initiative award to advance nav1 7 antisense therapy for chronic pain through early clinical trials read article april 13 2026 quiver bioscience receives strategic investment from the porta family to advance ube3a aso therapeutic program for dup15q syndrome read article february 23 2026 angelini pharma and quiver bioscience announce strategic research collaboration and licensing agreement to discover and advance novel therapeutics for genetic epilepsies read article behind our cutting edge technologies and drug discovery efforts is an amazing team discover jobs 2025 quiver bioscience privacy contact terms
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