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california san francisco menggunakan kombinasi teknik biokimia genetik dan pencitraan untuk menyelidiki fungsi apg9 dalam autophagy para peneliti menemukan bahwa apg9 memainkan peran penting dalam pembentukan autofagosom struktur yang bertanggung jawab untuk menelan dan menguraikan limbah seluler lebih lanjut penelitian tersebut menemukan bahwa mutasi pada apg9 dapat mengganggu proses autophagy yang menyebabkan penumpukan protein dan organel yang rusak di dalam sel akumulasi ini telah dikaitkan dengan perkembangan berbagai penyakit termasuk penyakit alzheimer penyakit parkinson dan kanker para peneliti juga mengidentifikasi protein spesifik yang disebut wipi2 yang berinteraksi dengan apg9 untuk mengatur pembentukan autofagosom dengan menargetkan interaksi antara apg9 dan wipi2 dimungkinkan untuk memodulasi autophagy dan berpotensi mengobati penyakit yang terkait dengan autophagy yang tidak diatur temuan ini mempunyai implikasi signifikan terhadap pemahaman kita tentang mekanisme 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