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ideas humans might never think of potentially speeding the race to new cures ai models are now able to generate atomic designs for drugs almost as easily as chatgpt can write a thank you note however when it came time to file for an all important patent to protect that new chemical structure the company made no mention of ai instead the patent names five humans including ceo alex zhavoronkov as the drug s inventors the discrepancy points to a fascinating wrinkle in intellectual property law no matter how fundamental an ai is to a discovery when it comes to winning rights to an invention it s humans and only humans who can take the credit us courts reached that conclusion after ryan abbott a partner at the la law firm brown neri smith khan brought a pro bono test case naming an ai called dabus as an inventor of a better food container whose intricate geometric surface lets it transfer heat well and stack easily because no human contributed to the design abbott argued that the ai should be named the inventor the case might have raised philosophical questions like whether ais deserve legal rights or what the true nature is of that eureka moment that leads to a better mousetrap but in 2022 an appeals court in washington dc said these metaphysical matters were beside the point instead it noted that us statutes describe an inventor as an individual the plain meaning of which is a human being since machines aren t people they can t be inventors case closed there needs to be a human inventor or there s no invention and no patent says sarah korman a patent attorney who is now chief business officer and legal officer of isomorphic labs an alphabet spinout with big ambitions for ai cures korman who made her remarks at mit technology review s emtech event last year added that there is no doubt our laws will need to evolve to keep pace with ai that s partly because no one is denying that ais can invent things in the future they may do so with less and less human intervention as the us patent and trademark office has itself acknowledged an ai system like other tools may perform acts that if performed by a human could constitute inventorship under our laws instead the key question going forward may actually be whether or not any human contributed enough to be named as an inventor abbott believes there could be legal challenges to ai generated drugs since one way to invalidate a patent is to show it has the wrong inventors listed abbott s worry is that if us policy excludes ai generated outputs from protection that could put a damper on future drug development already the us copyright office is refusing to grant copyrights to images and text generated by ai raising concerns from organizations like the motion picture association of america whose members are using those tools the point of our intellectual property laws is to encourage innovation abbott says it s right there in article 1 of the us constitution which says inventors and authors need to be given exclusive rights to their ideas for a limited time in order to promote the progress of science and the useful arts currently the us patent office seems to be taking a don t ask don t tell approach to the use of ai under the biden administration the agency published guidance to help applicants determine whether and when humans would truly qualify as co inventors of an ai discovery but after trump arrived in office it reversed course now the patent office says ai is merely a tool like a calculator no need to even mention it you can bet that pioneering ai drug companies are keeping humans in the loop at least for now and documenting everything carefully at insilico zhavoronkov says human chemists still have to synthesize the drugs create variants and test them on animals that s the person who is going to be named on the patent he says and even if you decided to completely roboticize this process including the experiments someone will still push the button and give the budget should pushing a button count as being an inventor abbott says that s a question for future legal cases what if i asked claude to cure cancer and it did he says i think it would be inappropriate to claim that i invented that this article first appeared in the checkup mit technology review s weekly biotech newsletter to receive it in your inbox every thursday and read articles like this first sign up here related story ai designed viruses are here and already killing bacteria read next when the biotech company insilico medicine used its computer models to propose a promising drug for pulmonary fibrosis it enthusiastically claimed in a press release that the molecule had been discovered by its generative ai platform insilico leads a pack of companies using ai to rapidly come up with drug ideas humans might never think of potentially speeding the race to new cures ai models are now able to generate atomic designs for drugs almost as easily as chatgpt can write a thank you note however when it came time to file for an all important patent to protect that new chemical structure the company made no mention of ai instead the patent names five humans including ceo alex zhavoronkov as the drug s inventors the discrepancy points to a fascinating wrinkle in intellectual property law no matter how fundamental an ai is to a discovery when it comes to winning rights to an invention it s humans and only humans who can take the credit us courts reached that conclusion after ryan abbott a partner at the la law firm brown neri smith khan brought a pro bono test case naming an ai called dabus as an inventor of a better food container whose intricate geometric surface lets it transfer heat well and stack easily because no human contributed to the design abbott argued that the ai should be named the inventor the case might have raised philosophical questions like whether ais deserve legal rights or what the true nature is of that eureka moment that leads to a better mousetrap but in 2022 an appeals court in washington dc said these metaphysical matters were beside the point instead it noted that us statutes describe an inventor as an individual the plain meaning of which is a human being since machines aren t people they can t be inventors case closed there needs to be a human inventor or there s no invention and no patent says sarah korman a patent attorney who is now chief business officer and legal officer of isomorphic labs an alphabet spinout with big ambitions for ai cures korman who made her remarks at mit technology review s emtech event last year added that there is no doubt our laws will need to evolve to keep pace with ai that s partly because no one is denying that ais can invent things in the future they may do so with less and less human intervention as the us patent and trademark office has itself acknowledged an ai system like other tools may perform acts that if performed by a human could constitute inventorship under our laws instead the key question going forward may actually be whether or not any human contributed enough to be named as an inventor abbott believes there could be legal challenges to ai generated drugs since one way to invalidate a patent is to show it has the wrong inventors listed abbott s worry is that if us policy excludes ai generated outputs from protection that could put a damper on future drug development already the us copyright office is refusing to grant copyrights to images and text generated by ai raising concerns from organizations like the motion picture association of america whose members are using those tools the point of our intellectual property laws is to encourage innovation abbott says it s right there in article 1 of the us constitution which says inventors and authors need to be given exclusive rights to their ideas for a limited time in order to promote the progress of science and the useful arts currently the us patent office seems to be taking a don t ask don t tell approach to the use of ai under the biden administration the agency published guidance to help applicants determine whether and when humans would truly qualify as co inventors of an ai discovery but after trump arrived in office it reversed course now the patent office says ai is merely a tool like a calculator no need to even mention it you can bet that pioneering ai drug companies are keeping humans in the loop at least for now and documenting everything carefully at insilico zhavoronkov says human chemists still have to synthesize the drugs create variants and test them on animals that s the person who is going to be named on the patent he says and even if you decided to completely roboticize this process including the experiments someone will still push the button and give the budget should pushing a button count as being an inventor abbott says that s a question for future legal cases what if i asked claude to cure cancer and it did he says i think it would be inappropriate to claim that i invented that this article first appeared in the checkup mit technology review s weekly biotech newsletter to receive it in your inbox every thursday and read articles like this first sign up here related story microsoft says ai can create zero day threats in biology read next when the biotech company insilico medicine used its computer models to propose a promising drug for pulmonary fibrosis it enthusiastically claimed in a press release that the molecule had been discovered by its generative ai platform insilico leads a pack of companies using ai to rapidly come up with drug ideas humans might never think of potentially speeding the race to new cures ai models are now able to generate atomic designs for drugs almost as easily as chatgpt can write a thank you note however when it came time to file for an all important patent to protect that new chemical structure the company made no mention of ai instead the patent names five humans including ceo alex zhavoronkov as the drug s inventors the discrepancy points to a fascinating wrinkle in intellectual property law no matter how fundamental an ai is to a discovery when it comes to winning rights to an invention it s humans and only humans who can take the credit us courts reached that conclusion after ryan abbott a partner at the la law firm brown neri smith khan brought a pro bono test case naming an ai called dabus as an inventor of a better food container whose intricate geometric surface lets it transfer heat well and stack easily because no human contributed to the design abbott argued that the ai should be named the inventor the case might have raised philosophical questions like whether ais deserve legal rights or what the true nature is of that eureka moment that leads to a better mousetrap but in 2022 an appeals court in washington dc said these metaphysical matters were beside the point instead it noted that us statutes describe an inventor as an individual the plain meaning of which is a human being since machines aren t people they can t be inventors case closed there needs to be a human inventor or there s no invention and no patent says sarah korman a patent attorney who is now chief business officer and legal officer of isomorphic labs an alphabet spinout with big ambitions for ai cures korman who made her remarks at mit technology review s emtech event last year added that there is no doubt our laws will need to evolve to keep pace with ai that s partly because no one is denying that ais can invent things in the future they may do so with less and less human intervention as the us patent and trademark office has itself acknowledged an ai system like other tools may perform acts that if performed by a human could constitute inventorship under our laws instead the key question going forward may actually be whether or not any human contributed enough to be named as an inventor abbott believes there could be legal challenges to ai generated drugs since one way to invalidate a patent is to show it has the wrong inventors listed abbott s worry is that if us policy excludes ai generated outputs from protection that could put a damper on future drug development already the us copyright office is refusing to grant copyrights to images and text generated by ai raising concerns from organizations like the motion picture association of america whose members are using those tools the point of our intellectual property laws is to encourage innovation abbott says it s right there in article 1 of the us constitution which says inventors and authors need to be given exclusive rights to their ideas for a limited time in order to promote the progress of science and the useful arts currently the us patent office seems to be taking a don t ask don t tell approach to the use of ai under the biden administration the agency published guidance to help applicants determine whether and when humans would truly qualify as co inventors of an ai discovery but after trump arrived in office it reversed course now the patent office says ai is merely a tool like a calculator no need to even mention it you can bet that pioneering ai drug companies are keeping humans in the loop at least for now and documenting everything carefully at insilico zhavoronkov says human chemists still have to synthesize the drugs create variants and test them on animals that s the person who is going to be named on the patent he says and even if you decided to completely roboticize this process including the experiments someone will still push the button and give the budget should pushing a button count as being an inventor abbott says that s a question for future legal cases what if i asked claude to cure cancer and it did he says i think it would be inappropriate to claim that i invented that this article first appeared in the checkup mit technology review s weekly biotech newsletter to receive it in your inbox every thursday and read articles like this first sign up here sign up to get the checkup weekly in your inbox enter your email sign up for free more newsletters explainers mit technology review explains let our writers untangle the complex messy world of technology to help you understand what s coming next in our popular explainer series previous slide next slide biotechnology and health inside interoception the hidden sense of how you feel inside researchers are decoding how signals move between body and brain with implications for how we understand and treat conditions from obesity to anxiety biotechnology and health here s what you need to know about the cruise ship hantavirus outbreak and why health experts believe it can be contained climate change and energy what do new nuclear reactors mean for waste new designs mean new strategies for managing spent fuel biotechnology and health peptides are everywhere here s what you need to know the compounds have exploded in popularity but big questions about safety and effectiveness are still unresolved artificial intelligence this is the most misunder...