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conditioned, setting, conferring, down, protect, reperfusion, forces, vesicles, called, transcribed, translated, transported, production, turn, takes, maximal, occurs, around, returns, baseline, weibel, palade, bodies, repeats, separate, whereas, cytosolic, derives, flanks, cassette, epidermal, repeat, units, intracellular, cytoplasmic, tail, cyto, three, dimensional, determined, resolution, reveals, limited, coordination, predicted, lectins, analysis, indicates, amino, side, chains, neunacα2, glcnac, tetrasaccharide, sushi, terminal, known, cd62, member, ucsc, np_035475, np_000441, nm_011345, nm_000450, mrna, q00690, p16581, uniprot, 20339, 6401, entrez, species, oma, ncbi, databases, orthologs, quickgo, amigo, actin, filament, based, internalization, heterophilic, via, extracellular, space, clathrin, coated, pit, raft, caveola, perinuclear, cytoplasm, cortical, cytoskeleton, cellular, metal, ion, sialic, oligosaccharide, ontology, biogps, lip, atrioventricular, ileal, semi, lunar, 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agents such as rrd 251 that can target activity of e2f1 may have potential therapeutic benefit against cigarette smoke induced atherosclerosis 47 cerebral aneurysm edit it s also found that e selectin expression increased in human ruptured cerebral aneurysm tissues e selectin might be an important factor involved in the process of cerebral aneurysm formation and rupture by promoting inflammation and weakening cerebral artery walls 48 as a biomarker edit e selectin is also an emerging biomarker for the metastatic potential of some cancers including colorectal cancer and recurrences 49 references edit 1 2 3 grch38 ensembl release 89 ensg00000007908 ensembl may 2017 1 2 3 grcm38 ensembl release 89 ensmusg00000026582 ensembl may 2017 human pubmed reference national center for biotechnology information u s national library of medicine mouse pubmed reference national center for biotechnology information u s national library of medicine collins t williams a johnston gi kim j eddy r shows t et al february 1991 structure and chromosomal location of the gene for endothelial leukocyte adhesion molecule 1 the journal of biological chemistry 266 4 2466 73 doi 10 1016 s0021 9258 18 52267 5 pmid 1703529 graves bj crowther rl chandran c rumberger jm li s huang ks et al february 1994 insight into e selectin ligand interaction from the crystal structure and mutagenesis of the lec egf domains nature 367 6463 532 8 bibcode 1994natur 367 532g doi 10 1038 367532a0 pmid 7509040 s2cid 4338500 somers ws tang j shaw gd camphausen rt october 2000 insights into the molecular basis of leukocyte tethering and rolling revealed by structures of p and e selectin bound to sle x and psgl 1 cell 103 3 467 79 doi 10 1016 s0092 8674 00 00138 0 pmid 11081633 s2cid 12719907 cummings rd 2008 selectins in varki a cummings rd esko jd freeze hh stanley p bertozzi cr hart gw etzler me eds essentials of glycobiology 2nd ed plainview n y cold spring harbor laboratory press isbn 978 0 87969 770 9 janeway c 2005 immunobiology the immune system in health and disease new york garland science isbn 0 8153 4101 6 1 2 leeuwenberg jf smeets ef neefjes jj shaffer ma cinek t jeunhomme tm et al december 1992 e selectin and intercellular adhesion molecule 1 are released by activated human endothelial cells in vitro immunology 77 4 543 9 pmc 1421640 pmid 1283598 huang rb eniola adefeso o 2012 shear stress modulation of il 1β induced e selectin expression in human endothelial cells plos one 7 2 e31874 bibcode 2012ploso 731874h doi 10 1371 journal pone 0031874 pmc 3286450 pmid 22384091 andrade cm sá mf toloi mr april 2012 effects of phytoestrogens derived from soy bean on expression of adhesion molecules on huvec climacteric 15 2 186 94 doi 10 3109 13697137 2011 582970 pmid 22066752 s2cid 29123853 1 2 3 robbins sl cotran rs kumar v collins t 1999 robbins pathologic basis of disease philadelphia wb saunders isbn 0 7216 7335 x zou x shinde patil vr dagia nm smith la wargo mj interliggi ka et al august 2005 psgl 1 derived from human neutrophils is a high efficiency ligand for endothelium expressed e selectin under flow american journal of physiology cell physiology 289 2 c415 24 doi 10 1152 ajpcell 00289 2004 pmid 15814589 kannagi r izawa m koike t miyazaki k kimura n may 2004 carbohydrate mediated cell adhesion in cancer metastasis and angiogenesis cancer science 95 5 377 84 doi 10 1111 j 1349 7006 2004 tb03219 x pmc 11159147 pmid 15132763 s2cid 27761640 dimitroff cj descheny l trujillo n kim r nguyen v huang w et al july 2005 identification of leukocyte e selectin ligands p selectin glycoprotein ligand 1 and e selectin ligand 1 on human metastatic prostate tumor cells cancer research 65 13 5750 60 doi 10 1158 0008 5472 can 04 4653 pmc 1472661 pmid 15994950 gout s tremblay pl huot j 2008 selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis clinical experimental metastasis 25 4 335 44 doi 10 1007 s10585 007 9096 4 pmid 17891461 s2cid 11272581 shirure vs liu t delgadillo lf cuckler cm tees df benencia f et al january 2015 cd44 variant isoforms expressed by breast cancer cells are functional e selectin ligands under flow conditions american journal of physiology cell physiology 308 1 c68 78 doi 10 1152 ajpcell 00094 2014 pmc 4281670 pmid 25339657 shirure vs reynolds nm burdick mm 2012 mac 2 binding protein is a novel e selectin ligand expressed by breast cancer cells plos one 7 9 e44529 bibcode 2012ploso 744529s doi 10 1371 journal pone 0044529 pmc 3435295 pmid 22970241 shirure vs henson ka schnaar rl nimrichter l burdick mm march 2011 gangliosides expressed on breast cancer cells are e selectin ligands biochemical and biophysical research communications 406 3 423 9 bibcode 2011bbrc 406 423s doi 10 1016 j bbrc 2011 02 061 pmid 21329670 nimrichter l burdick mm aoki k laroy w fierro ma hudson sa et al november 2008 e selectin receptors on human leukocytes blood 112 9 3744 52 doi 10 1182 blood 2008 04 149641 pmc 2572800 pmid 18579791 janeway s immunobiology 8th edition pattern recognition by cells of the innate immunity system chapter 3 page 83 bevilacqua mp pober js mendrick dl cotran rs gimbrone ma december 1987 identification of an inducible endothelial leukocyte adhesion molecule proceedings of the national academy of sciences of the united states of america 84 24 9238 42 bibcode 1987pnas 84 9238b doi 10 1073 pnas 84 24 9238 pmc 299728 pmid 2827173 walz g aruffo a kolanus w bevilacqua m seed b november 1990 recognition by elam 1 of the sialyl lex determinant on myeloid and tumor cells science 250 4984 1132 5 bibcode 1990sci 250 1132w doi 10 1126 science 1701275 pmid 1701275 khatib am kontogiannea m fallavollita l jamison b meterissian s brodt p march 1999 rapid induction of cytokine and e selectin expression in the liver in response to metastatic tumor cells cancer research 59 6 1356 61 pmid 10096570 sawada r tsuboi s fukuda m january 1994 differential e selectin dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials the journal of biological chemistry 269 2 1425 31 doi 10 1016 s0021 9258 17 42275 7 pmid 7507108 dimitroff cj lechpammer m long woodward d kutok jl august 2004 rolling of human bone metastatic prostate tumor cells on human bone marrow endothelium under shear flow is mediated by e selectin cancer research 64 15 5261 9 doi 10 1158 0008 5472 can 04 0691 pmid 15289332 s2cid 11632075 laferrière j houle f huot j 2004 adhesion of ht 29 colon carcinoma cells to endothelial cells requires sequential events involving e selectin and integrin beta4 clinical experimental metastasis 21 3 257 64 doi 10 1023 b clin 0000037708 09420 9a pmid 15387376 s2cid 22354589 barthel sr hays dl yazawa em opperman m walley kc nimrichter l et al january 2013 definition of molecular determinants of prostate cancer cell bone extravasation cancer research 73 2 942 52 doi 10 1158 0008 5472 can 12 3264 pmc 3548951 pmid 23149920 esposito m kang y february 2014 targeting tumor stromal interactions in bone metastasis pharmacology therapeutics 141 2 222 33 doi 10 1016 j pharmthera 2013 10 006 pmc 3947254 pmid 24140083 sipkins da wei x wu jw runnels jm côté d means tk et al june 2005 in vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment nature 435 7044 969 73 bibcode 2005natur 435 969s doi 10 1038 nature03703 pmc 2570168 pmid 15959517 läubli h borsig l february 2010 selectins as mediators of lung metastasis cancer microenvironment 3 1 97 105 doi 10 1007 s12307 010 0043 6 pmc 2990482 pmid 21209777 esposito m mondal n greco tm wei y spadazzi c lin sc et al may 2019 bone vascular niche e selectin induces mesenchymal epithelial transition and wnt activation in cancer cells to promote bone metastasis nature cell biology 21 5 627 639 doi 10 1038 s41556 019 0309 2 pmc 6556210 pmid 30988423 esposito m mondal n greco tm wei y spadazzi c lin sc et al may 2019 bone vascular niche e selectin induces mesenchymal epithelial transition and wnt activation in cancer cells to promote bone metastasis nature cell biology 21 5 627 639 doi 10 1038 s41556 019 0309 2 pmc 6556210 pmid 30988423 taverna d moher h crowley d borsig l varki a hynes ro january 2004 increased primary tumor growth in mice null for beta3 or beta3 beta5 integrins or selectins proceedings of the national academy of sciences of the united states of america 101 3 763 8 bibcode 2004pnas 101 763t doi 10 1073 pnas 0307289101 pmc 321755 pmid 14718670 price tt burness ml sivan a warner mj cheng r lee ch et al may 2016 dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone science translational medicine 8 340 340ra73 doi 10 1126 scitranslmed aad4059 pmc 8722465 pmid 27225183 s2cid 31317455 winkler ig barbier v nowlan b jacobsen rn forristal ce patton jt et al november 2012 vascular niche e selectin regulates hematopoietic stem cell dormancy self renewal and chemoresistance nature medicine 18 11 1651 7 doi 10 1038 nm 2969 pmid 23086476 s2cid 5593456 esposito m mondal n greco tm wei y spadazzi c lin sc et al may 2019 bone vascular niche e selectin induces mesenchymal epithelial transition and wnt activation in cancer cells to promote bone metastasis nature cell biology 21 5 627 639 doi 10 1038 s41556 019 0309 2 pmc 6556210 pmid 30988423 glycomimetics announces plans to initiate breast cancer trial to evaluate gmi 1359 www businesswire com 2019 04 12 retrieved 2019 06 10 esposito m mondal n greco tm wei y spadazzi c lin sc et al may 2019 bone vascular niche e selectin induces mesenchymal epithelial transition and wnt activation in cancer cells to promote bone metastasis nature cell biology 21 5 627 639 doi 10 1038 s41556 019 0309 2 pmc 6556210 pmid 30988423 mai j huang y mu c zhang g xu r guo x et al august 2014 bone marrow endothelium targeted therapeutics for metastatic breast cancer journal of controlled release 187 22 9 doi 10 1016 j jconrel 2014 04 057 pmc 4109393 pmid 24818768 läubli h spanaus ks borsig l november 2009 selectin mediated activation of endothelial cells induces expression of ccl5 and promotes metastasis through recruitment of monocytes blood 114 20 4583 91 doi 10 1182 blood 2008 10 186585 pmid 19779041 visser lh november 2006 critical illness polyneuropathy and myopathy clinical features risk factors and prognosis european journal of neurology 13 11 1203 12 doi 10 1111 j 1468 1331 2006 01498 x pmid 17038033 s2cid 7557453 hu y chen x duan h hu y mu x 2009 chinese herbal medicinal ingredients inhibit secretion of il 6 il 8 e selectin and txb2 in lps induced rat intestinal microvascular endothelial cells immunopharmacology and immunotoxicology 31 4 550 5 doi 10 3109 08923970902814129 pmid 19874221 s2cid 207481204 komatsu t nagano k sugiura s hagiwara m tanigawa n abiko y et al july 2012 e selectin mediates porphyromonas gingivalis adherence to human endothelial cells infection and immunity 80 7 2570 6 doi 10 1128 iai 06098 11 pmc 3416463 pmid 22508864 fang f zhang w yang l wang z liu dg december 2011 pecam 1 and e selectin expression in vulnerable plague and their relationships to myocardial leu125val polymorphism of pecam 1 and ser128arg polymorphism of e selectin in patients with acute coronary syndrome zhonghua xin xue guan bing za zhi in chinese 39 12 1110 6 pmid 22336504 alamanda v singh s lawrence nj chellappan sp february 2012 nicotine mediated induction of e selectin in aortic endothelial cells requires src kinase and e2f1 transcriptional activity biochemical and biophysical research communications 418 1 56 61 bibcode 2012bbrc 418 56a doi 10 1016 j bbrc 2011 12 127 pmc 3273677 pmid 22240023 jia w wang r zhao j liu iy zhang d wang x et al november 2011 e selectin expression increased in human ruptured cerebral aneurysm tissues the canadian journal of neurological sciences 38 6 858 62 doi 10 1017 s0317167100012439 pmid 22030423 sato h usuda n kuroda m hashimoto s maruta m maeda k november 2010 significance of serum concentrations of e selectin and ca19 9 in the prognosis of colorectal cancer japanese journal of clinical oncology 40 11 1073 80 doi 10 1093 jjco hyq095 pmid 20576794 external links edit e selectin at the u s national library of medicine medical subject headings mesh v t e pdb gallery 1esl insight into e selectin slash ligand interaction from the crystal structure and mutagenesis of the lec slash egf domains 1g1t crystal structure of e selectin lectin egf domains complexed with slex v t e membrane proteins cell adhesion molecules calcium independent igsf cam n cam myelin protein zero icam 1 5 vcam 1 pe cam l1 family l1 cam nrcam nfasc chl1 nectin pvrl1 pvrl2 pvrl3 cadm1 cadm2 cadm3 cd155 integrins lfa 1 cd11a cd18 integrin alphaxbeta2 cd11c cd18 macrophage 1 antigen cd11b cd18 vla 4 cd49d cd29 glycoprotein iib iiia itga2b itgb3 calcium dependent cadherins classical cdh1 cdh2 cdh3 desmosomal desmoglein dsg1 dsg2 dsg3 dsg4 desmocollin dsc1 dsc2 dsc3 protocadherin pcdh1 pcdh15 pcdh19 unconventional ungrouped t cadherin cdh4 cdh5 cdh6 cdh8 cdh11 cdh12 cdh15 cdh16 cdh17 cdh9 cdh10 selectins e selectin l selectin p selectin other lymphocyte homing receptor cd44 l selectin integrin vla 4 lfa 1 carcinoembryonic antigen cd24 cd44 cd146 epcam v t e proteins clusters of differentiation see also list of human clusters of differentiation 1 50 1 a c 1a 1b 1d 1e 2 3 γ δ ε 4 5 6 7 8 a 9 10 11 a b c d 13 14 15 16 a b 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 a b 33 34 35 36 37 38 39 40 41 42 a b c d 43 44 45 46 47 48 49 a b c d e f 50 51 100 51 52 53 54 55 56 57 58 59 61 62 e l p 63 64 a b c 66 a b c d e f 68 69 70 71 72 73 74 78 79 a b 80 81 82 83 84 85 a d e h j k 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 150 101 102 103 104 105 106 107 a b 108 109 110 111 112 113 114 115 116 117 118 119 120 a b 121 a b 122 123 124 125 126 127 129 130 131 132 133 134 135 136 137 138 140b 141 142 143 144 146 147 148 150 151 200 151 152 153 154 155 156 a b c 157 158 a d e i k 159 a c 160 161 162 163 164 166 167 a b 168 169 170 171 172 a b g 174 177 178 179 a b 180 181 182 183 184 185 186 191 192 193 194 195 196 197 w198 w199 200 201 250 201 202b 204 205 206 207 208 209 w210 a b 212 213a 1 2 217 218 a b 220 221 222 223 224 225 226 227 228 229 230 233 234 235 a b 236 238 239 240ce 240d 241 243 244 246 247 248 249 251 300 252 253 254 256 257 258 261 262 263 264 265 266 267 268 269 271 272 273 274 275 276 278 279 280 281 282 283 284 286 288 289 290 292 w293 294 295 297 298 299 301 350 300a 301 302 303 304 305 306 307 309 312 314 315 316 317 318 320 321 322 324 325 326 327 328 329 331 332 333 334 335 336 337 338 339 340 344 349 350 351 371 351 352 353 354 355 357 358 360 361 362 363 364 365 366 367 368 369 370 371 category commons retrieved from https en wikipedia org w index php title e selectin oldid 1372860288 categories genes on human chromosome 1 cell adhesion proteins clusters of differentiation glycoproteins transmembrane receptors selectins biomarkers...
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