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165, tribendimidine, tebanicline, 6683, 5619, 5214, 2216, 1827, 1734, 1698, suxethonium, succinyldicholine, suxamethonium, succinylcholine, suberyldicholine, 180, 711, sofinicline, 894, 1553a, 1508y, sebacylcholine, 206553, sazetidine, rjr, 2429, rivanicline, pyrantel, pozanicline, 120, 596, 709, 829, 613, nndmai, 1738, morantel, mem, 908, 3487, levamisole, jnj, 39393406, ispronicline, gts, galantamine, 6124, 4473, ethoxysebacylcholine, epiboxidine, epibatidine, dimethylphenylpiperazinium, dianicline, desformylflustrabromine, cotinine, bromophenyl, butyrylcholine, butinoline, bephenium, hydroxynaphthoate, r17779, anatoxin, anatabine, anabasine, altinicline, 560, 418, 867, 744, 582, 941, 366, 833, chloronicotine, hiaa, nachrs, metabotropic, agn, 241751, saffron, transcrocetin, psychotridine, isethionate, mpep, metaphit, 27266, ipenoxazone, mlv, 6976, hodgkinsine, 115427, fpl, dexanabinol, αaa, conantokin, 869, arr, xylene, urethane, octanol, hexanol, volatile, cations, 213, 007, 004, nr2a, traxoprodil, 101606, safaprodil, 6981, 4304, rislenemdaz, cerc, 0657, radiprodil, rgh, 896, isoxsuprine, eliprodil, 101244, 174494, buphenine, nylidrin, besonprodil, nr2b, tenocyclidine, tabernanthine, sabeluzole, rolicyclidine, rimantadine, remacemide, propoxyphene, phencyclamine, meperidine, 137889, pcpr, noribogaine, nitromemantine, nefa, milnacipran, methoxphenidine, methoxetamine, levomilnacipran, levomethorphan, lanicemine, ketobemidone, indantadol, ibogamine, gacyclidine, fluorolintane, 17475, eticyclidine, etoxadrol, ephenidine, diphenidine, dieticyclidine, dextromethadone, dextrallorphan, dexoxadrol, delucemine, nps, 1506, 5161, budipine, 16247, arketamine, argiotoxin, 636, aptiganel, alazocine, skf, 10047, alaproclate, endopsychosin, pdhq, pcmo, pce, mdp, uncompetitive, mostly, putrescine, huperzine, diethylenetriamine, diaminopropane, 101676, arcaine, 9379, mrz, 576, 105519, 73068, 701324, 689560, harkoseride, 196771, gavestinel, 1328, cka, dcka, kyn, selfotel, sdz, 220581, ppda, perzinfotel, peaqx, pbpd, 17742, 12626, midafotel, cppene, 100453, 274614, 235959, 233053, cpp, 19755, 40116, 39551, 37849, ap7, ap5, apv, competitive, 718, plazinemdor, epipregnanolone, dehydroepiandrosterone, hydroxycholesterol, spermine, spermidine, neomycin, neboglamine, nebostinel, 687, 414, 966, dimethylglycine, dhpg, ccg, b6b21, acpd, acpc, acbd, fluoro, tetrazolylglycine, quinolinic, homoquinolinic, homocysteic, hca, amaa, 3763, ubp, 302, ns102, 382884, sym, 2081, 339434, kainic, atpa, iodowillardiine, bromowillardiine, kar, talampanel, rap, 219, irampanel, 53655, 52466, zonampanel, ym90k, fanapanel, mpqx, becampanel, atpo, tulrampator, 47445, 1632, 18986, pramiracetam, piracetam, pepa, oxiracetam, 26576, nooglutyl, mibampator, 451395, 503430, 451646, 404187, 395153, 392098, idra, hydrochlorothiazide, hctz, 1942, 1739, 717, farampator, 691, 24448, 614, 546, aniracetam, willardiine, boaa, fluorowillardiine, amino, hydroxy, isoxazolepropionic, ampar, lgics, trps, trifluoperazine, talniflumate, mepacrine, phenanthridine, ivacaftor, benzoquinoline, lonidamine, cystic, fibrosis, conductance, regulator, cftr, mefloquine, ethacrynic, dids, crofelemer, caccs, pctx1, ibuprofen, 317567, sensing, asics, solnatide, triamterene, benzamil, epithelial, enac, poneratoxin, grayanotoxins, ciguatoxins, batrachotoxin, atracotoxins, versutoxin, robustoxin, atracotoxin, aconitine, mint, evenamide, zetekitoxin, tetrodotoxin, saxitoxin, neosaxitoxin, suzetrigine, rg7893, 0287, raxatrigine, 05089771, 04531083, nktr, 171, 0276, funapide, dsp, 2230, 3161, analgesics, trimecaine, tetracaine, risocaine, proxymetacaine, propoxycaine, procaine, prilocaine, piperocaine, orthocaine, metabutoxycaine, meprylcaine, mepivacaine, iontocaine, hexylcaine, etidocaine, dimethocaine, cyclomethycaine, cinchocaine, chloroprocaine, butamben, butacaine, ropivacaine, levobupivacaine, bupivacaine, benzocaine, articaine, amylocaine, fbt, local, valproic, semisodium, oxitriptyline, 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2 adrenergic receptor agonists e g clonidine tizanidine antipsychotics e g quetiapine olanzapine risperidone chlorpromazine ashwagandha benzoctamine cannabinoids e g cannabis dronabinol thc nabilone zenivol chamomile fenadiazole gaba a receptor agonists e g gaboxadol thip muscimol amanita muscaria gaba b receptor agonists e g sodium oxybate γ hydroxybutyrate ghb baclofen phenibut gaba reuptake inhibitors e g tiagabine gabapentinoids e g gabapentin gabapentin enacarbil pregabalin hops lavender menthyl isovalerate opioids e g hydrocodone oxycodone morphine passion flower pellotine scopolamine serotonin precursors tryptophan 5 hydroxytryptophan 5 htp oxitriptan phenylpiperazines e g trazodone niaprazine theanine tributyrin tricyclic antidepressants e g amitriptyline doxepin trimipramine tetracyclic antidepressants e g mirtazapine valnoctamide who em withdrawn from market clinical trials phase iii never to phase iii pharmacodynamics v t e gaba a receptor positive modulators alcohols brometone butanol chloralodol chlorobutanol cloretone ethanol alcohol alcoholic drink ethchlorvynol isobutanol isopropanol menthol methanol methylpentynol pentanol petrichloral propanol tert butanol 2m2p tert pentanol 2m2b tribromoethanol trichloroethanol triclofos trifluoroethanol barbiturates dmbb allobarbital alphenal amobarbital aprobarbital barbexaclone barbital benzobarbital benzylbutylbarbiturate brallobarbital brophebarbital butabarbital secbutabarbital butalbital buthalital butobarbital butallylonal carbubarb crotylbarbital cyclobarbital cyclopentobarbital difebarbamate enallylpropymal ethallobarbital eterobarb febarbamate heptabarb heptobarbital hexethal hexobarbital methallatal metharbital methitural methohexital methylphenobarbital narcobarbital nealbarbital pentobarbital phenallymal phenobarbital phetharbital primidone probarbital propallylonal propylbarbital proxibarbital reposal secobarbital sigmodal spirobarbital talbutal tetrabamate tetrabarbital thialbarbital thiamylal thiobarbital thiobutabarbital thiopental thiotetrabarbital valofane vinbarbital vinylbital benzodiazepines 2 oxoquazepam 3 hydroxyphenazepam adinazolam alprazolam arfendazam avizafone bentazepam bretazenil bromazepam bromazolam brotizolam camazepam carburazepam chlordiazepoxide ciclotizolam cinazepam cinolazepam clazolam climazolam clobazam clonazepam clonazolam cloniprazepam clorazepate clotiazepam cloxazolam cp 1414s cyprazepam delorazepam demoxepam diazepam diclazepam dimdazenil doxefazepam elfazepam estazolam ethyl carfluzepate ethyl dirazepate ethyl loflazepate etizolam fg 8205 fletazepam flubromazepam flubromazolam fludiazepam flunitrazepam flunitrazolam flurazepam flutazolam flutemazepam flutoprazepam fosazepam gidazepam halazepam haloxazolam iclazepam imidazenil irazepine ketazolam lofendazam lopirazepam loprazolam lorazepam lormetazepam meclonazepam medazepam menitrazepam metaclazepam mexazolam midazolam motrazepam n desalkylflurazepam nifoxipam nimetazepam nitrazepam nitrazepate nitrazolam nordazepam nortetrazepam oxazepam oxazolam phenazepam pinazepam pivoxazepam prazepam premazepam proflazepam pyrazolam qh ii 66 quazepam reclazepam remimazolam rilmazafone ripazepam ro48 6791 ro48 8684 sh 053 r ch3 2 f sulazepam temazepam tetrazepam tolufazepam triazolam triflubazam triflunordazepam ro5 2904 tuclazepam uldazepam zapizolam zolazepam zomebazam carbamates carisbamate carisoprodol clocental cyclarbamate difebarbamate emylcamate ethinamate febarbamate felbamate hexapropymate hydroxyphenamate lorbamate mebutamate meprobamate nisobamate pentabamate phenprobamate procymate styramate tetrabamate tybamate flavonoids 6 methylapigenin ampelopsin dihydromyricetin apigenin baicalein baicalin catechin egc egcg hispidulin linarin luteolin rc ome skullcap constituents e g baicalin wogonin imidazoles etomidate metomidate methoxyetomidate propoxate isopropoxate butomidate iso butomidate sec butomidate cf2 etomidate cf3 etomidate cf3 propoxate flutomidate 2 6 dichloro 3 fluoroetomidate kava constituents 10 methoxyyangonin 11 methoxyyangonin 11 hydroxyyangonin desmethoxyyangonin 11 methoxy 12 hydroxydehydrokavain 7 8 dihydroyangonin kavain 5 hydroxykavain 5 6 dihydroyangonin 7 8 dihydrokavain 5 6 7 8 tetrahydroyangonin 5 6 dehydromethysticin methysticin 7 8 dihydromethysticin yangonin monoureides acecarbromal apronal apronalide bromisoval carbromal capuride ectylurea neurosteroids acebrochol allopregnanolone brexanolone alfadolone alfaxalone 3α androstanediol androstenol androsterone certain anabolic androgenic steroids cholesterol cortisol hydrocortisone dhdoc 3α dhp 5α dhp 5β dhp dht etiocholanolone etx 155 ganaxolone hydroxydione lpcn 1154 minaxolone nora 520 org 20599 org 21465 p1 185 posovolone prax 114 pregnanolone eltanolone progesterone renanolone sage 105 sage 324 sage 516 sage 689 sage 872 testosterone thdoc zuranolone nonbenzodiazepines cyclopyrrolones eszopiclone pagoclone pazinaclone suproclone suriclone zopiclone imidazopyridines alpidem ds 1 necopidem saripidem zolpidem pyrazolopyrimidines divaplon fasiplon indiplon lorediplon ocinaplon panadiplon taniplon zaleplon others adipiplon axs 17 baer 101 azd 7325 cgs 8216 cgs 9896 cgs 13767 cgs 20625 cl 218 872 cp 615 003 ctp 354 elb 139 enx 102 tpa 023b gbld 345 imepitoin jm 1232 l 838 417 lirequinil ro41 3696 miltirone rosmariquinone ns 2664 ns 2710 ns 11394 ns 11821 pipequaline rod 188 rwj 51204 sb 205 384 sx 3228 tgsc01aa tp 003 tpa 023 tp 13 u 89843a u 90042 viqualine y 23684 phenols cipepofol fospropofol propofol propofol hemisuccinate thymol piperidinediones glutethimide methyprylon piperidione pyrithyldione pyrazolopyridines cartazolate etazolate ici 190 622 tracazolate quinazolinones afloqualone cloroqualone diproqualone etaqualone mebroqualone mecloqualone methaqualone methylmethaqualone nitromethaqualone sl 164 volatiles gases acetone acetophenone acetylglycinamide chloral hydrate aliflurane benzene butane butylene centalun chloral chloral betaine chloral hydrate chloroform cryofluorane desflurane dichloralphenazone dichloromethane diethyl ether enflurane ethyl chloride ethylene fluroxene gasoline halopropane halothane isoflurane kerosine methoxyflurane methoxypropane nitric oxide nitrogen nitrous oxide norflurane paraldehyde propane propylene roflurane sevoflurane synthane teflurane toluene trichloroethane methyl chloroform trichloroethylene vinyl ether others unsorted 3 hydroxybutanal α emtbl aa 29504 alogabat avermectins e g ivermectin bromide compounds e g lithium bromide potassium bromide sodium bromide carbamazepine chloralose chlormezanone clomethiazole darigabat deabl deuterated etifoxine dihydroergolines e g dihydroergocryptine dihydroergosine dihydroergotamine ergoloid dihydroergotoxine ds2 efavirenz etazepine etifoxine fenamates e g flufenamic acid mefenamic acid niflumic acid tolfenamic acid fluoxetine flupirtine hopantenic acid krm ii 81 lanthanum lavender oil lignans e g 4 o methylhonokiol honokiol magnolol obovatol loreclezole menthyl isovalerate validolum monastrol nezavist dcuk oet nicotinic acid nicotinamide ntx 1955 ro 7308480 org 25 435 phenytoin propanidid retigabine ezogabine safranal seproxetine stiripentol sulfonylalkanes e g sulfonmethane sulfonal tetronal trional terpenoids e g borneol topiramate valerian constituents e g isovaleric acid isovaleramide valerenic acid valerenol unsorted benzodiazepine site positive modulators α pinene mrk 409 mk 0343 tcs 1105 tcs 1205 see also receptor signaling modulators gaba receptor modulators gaba metabolism transport modulators v t e glycine receptor modulators receptor ligands glyr tooltip glycine receptor agonists β alanine β aba baba β aiba caesium d alanine d serine gaba glycine hypotaurine ivermectin l alanine l proline l serine l threonine mdl 27531 milacemide picolinic acid propofol quisqualamine sarcosine taurine positive modulators alcohols e g brometone chlorobutanol chloretone ethanol alcohol tert butanol 2m2p tribromoethanol trichloroethanol trifluoroethanol alkylbenzene sulfonate anandamide barbiturates e g pentobarbital sodium thiopental chlormethiazole d12 116 dihydropyridines e g nicardipine etomidate ginseng constituents e g ginsenosides e g ginsenoside rf glutamic acid glutamate ivermectin ketamine neuroactive steroids e g alfaxolone pregnenolone eltanolone pregnenolone acetate minaxolone org 20599 nitrous oxide penicillin g propofol tamoxifen tetrahydrocannabinol triclofos tropeines e g atropine bemesetron cocaine ly 278584 tropisetron zatosetron volatiles gases e g chloral hydrate chloroform desflurane diethyl ether ether enflurane halothane isoflurane methoxyflurane sevoflurane toluene trichloroethane methyl chloroform trichloroethylene xenon zinc antagonists 2 aminostrychnine 2 nitrostrychnine 4 phenyl 4 formyl n methylpiperidine αembtl bicuculline brucine cacotheline caffeine colchicine colubrine cyanotriphenylborate dendrobine diaboline endocannabinoids e g 2 ag anandamide aea gaboxadol thip gelsemine iso thaz isobutyric acid isonipecotic acid isostrychnine laudanosine n methylbicuculline n methylstrychnine n n dimethylmuscimol nipecotic acid pitrazepin pseudostrychnine quinolines e g 4 hydroxyquinoline 4 hydroxyquinoline 3 carboxylic acid 5 7 ciqa 7 ciq 7 tfq 7 tfqa ru 5135 sinomenine strychnine thaz thiocolchicoside tutin negative modulators amiloride benzodiazepines e g bromazepam clonazepam diazepam flunitrazepam flurazepam corymine cyanotriphenylborate daidzein dihydropyridines e g nicardipine nifedipine nitrendipine furosemide genistein ginkgo constituents e g bilobalide ginkgolides e g ginkgolide a ginkgolide b ginkgolide c ginkgolide j ginkgolide m imipramine nbqx neuroactive steroids e g 3α androsterone sulfate 3β androsterone sulfate deoxycorticosterone dhea sulfate pregnenolone sulfate progesterone opioids e g codeine dextromethorphan dextrorphan levomethadone levorphanol morphine oripavine pethidine thebaine picrotoxin i e picrotin and picrotoxinin pmba riluzole tropeines e g bemesetron ly 278584 tropisetron zatosetron verapamil zinc nmdar tooltip n methyl d aspartate receptor see here instead transporter blockers glyt1 tooltip sodium and chloride dependent glycine transporter 1 acppb alx 5407 nfps asp2535 bitopertin rg1678 ro4917838 cp 802079 ethanol alcohol glycyldodecylamide gsk1018921 iclepertin ly 2365109 mardepodect org 24598 org 25935 sch 900435 pesampator biib 104 pf 04958242 pf 03463275 sarcosine sng 12 synapsinae ssr 103 800 ssr 504 734 tilapertin glyt2 tooltip glycine transporter 2 alx 1393 amoxapine ethanol alcohol nagly opiranserin vvz 149 org 25543 vvz 368 see also receptor signaling modulators gaba receptor modulators gaba a receptor positive modulators ionotropic glutamate receptor modulators v t e ion channel modulators calcium vdccs tooltip voltage dependent calcium channels blockers l type selective dihydropyridines amlodipine telmisartan and indapamide aranidipine azelnidipine barnidipine clevidipine cronidipine darodipine dexniguldipine elgodipine elnadipine felodipine flordipine furnidipine iganidipine isradipine lacidipine lemildipine lercanidipine levamlodipine levniguldipine manidipine mepirodipine mesudipine nicardipine nifedipine niguldipine niludipine nilvadipine nimodipine nisoldipine nitrendipine olradipine oxodipine palonidipine pranidipine ryodipine riodipine sagandipine sornidipine teludipine tiamdipine trombodipine vatanidipine diltiazem derivatives clentiazem diltiazem iprotiazem nictiazem siratiazem phenylalkylamines anipamil dagapamil devapamil dexverapamil emopamil etripamil falipamil gallopamil levemopamil nexopamil norverapamil ronipamil tiapamil verapamil others ah 1058 brinazarone budiodarone celivarone cyproheptadine dronedarone fantofarone sr 33805 tetrahydropalmatine n type selective ω conotoxins ω conotoxin gvia caroverine huwentoxin xvi leconotide ω conotoxin cvid pd 173212 ralfinamide safinamide z160 ziconotide ω conotoxin mviia p type selective ω agatoxin iva ω agatoxin ivb r type selective snx 482 t type selective abt 639 ml 218 niflumic acid nnc 55 0396 protx i z944 zonisamide non selective ω agatoxin tk ω conotoxin mviic benidipine bepridil cilnidipine cinnarizine dotarizine efonidipine flunarizine lamotrigine levetiracetam lomerizine loperamide mibefradil np078585 ruthenium red trox 1 α 2 δ subunit selective gabapentinoids 4 methylpregabalin arbaclofen arbaclofen placarbil atagabalin baclofen gabapentin gabapentin enacarbil imagabalin mirogabalin pd 200 347 pd 217 014 pd 299 685 phenibut pregabalin others unsorted bencyclane berbamine bevantolol canadine carboxyamidotriazole cycleanine dauricine dimeditiapramine diproteverine enpiperate eperisone elpetrigine ethadione ethanol alcohol ethosuximide fasudil fendiline fostedil imepitoin jtv 519 lidoflazine magnesium manoalide mesuximide monatepil naftopidil ochratoxin a osthol otilonium bromide paramethadione phensuximide pinaverium bromide prenylamine rhynchophylline sesamodil silperisone sipatrigine terodiline tetrandrine tolperisone trimethadione valperinol activators l type selective bay k8644 potassium vgkcs tooltip voltage gated potassium channels blockers 3 4 diaminopyridine amifampridine 4 aminopyridine fampridine dalfampridine adekalant almokalant amiodarone azimilide bretylium bunaftine charybdotoxin clamikalant conotoxins dalazatide dendrotoxin dofetilide dronedarone e 4031 hanatoxin hgetx1 hstx1 ibutilide inakalant kaliotoxin linopirdine lolitrem b maurotoxin nifekalant notoxin paxilline pinokalant quinidine shk 186 sotalol tedisamil terikalant tetraethylammonium vernakalant herg kcnh2 k v 11 1 specific ajmaline amiodarone ammtx3 astemizole azaspiracid azd1305 azimilide bedaquiline bekm 1 bmtx3 brl 32872 chlorpromazine cisapride clarithromycin darifenacin dextropropoxyphene diallyl trisulfide domperidone e 4031 ergtoxins erythromycin gigactonine haloperidol ketoconazole norpropoxyphene orphenadrine pimozide pnu 282 987 promethazine quinidine ranolazine roxithromycin sertindole solifenacin tamulotoxin terodiline terfenadine thioridazine tolterodine vanoxerine vernakalant kcnq k v 7 specific linopirdine spooky toxin sstx xe 991 activators kcnq k v 7 specific azetukalner encukalner cb03 154 fluoxakalner flupirtine opakalim pynegabine retigabine ezogabine irks tooltip inwardly rectifying potassium channel blockers k atp tooltip atp sensitive potassium channel specific acetohexamide carbutamide chlorpropamide glibenclamide glyburide glibornuride glicaramide gliclazide glimepiride glipizide gliquidone glisoxepide glyclopyramide glycyclamide metahexamide mitiglinide nateglinide repaglinide tolazamide tolbutamide girk tooltip g protein coupled inwardly rectifying potassium channel specific barium caramiphen cloperastine clozapine dextromethorphan ethosuximide ifenprodil tertiapin tipepidine activators k atp tooltip atp sensitive potassium channel specific aprikalim bimakalim cromakalim diazoxide emakalim levcromakalim mazokalim minoxidil minoxidil sulfate naminidil nicorandil pinacidil rilmakali...
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