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site title: Security Update: Meltdown and Spectre Vulnerabilities - Inside DNAnexus

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description=On January 3rd, a new class of security flaw was reported that impacts most processors including those that are used by Cloud Service Providers (CSPs), such as Amazon AWS and Microsoft Azure.  The issue exploits the speculative execution optimizations in processors as a side-channel attack that leak kernel memory (Meltdown, CVE-2017-5754) or user memory (Spectre,… Read more Security Update: Meltdown and Spectre Vulnerabilities;

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security update meltdown and spectre vulnerabilities inside dnanexus skip to content platform show submenu for platform platform the dnanexus platform manage your data organized and managed in one place analyze a comprehensive suite of bioinformatics tools collaborate powering collaborative exploration and discovery security compliance comply with regulations standards and frameworks latest press releases our latest announcements and coverage read more solutions show submenu for solutions industries pharmaceutical biotech academic medical center clinical diagnostics commercial data businesses biobanks population programs global health authorities solutions ngs data analysis translational informatics population genomics trusted regulatory spaces trusted research environments services professional services managed services partners show submenu for partners partners cloud partners technology partners services partners data biobank partners instrument partners uk biobank heading learn 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population programs global health authorities solutions ngs data analysis translational informatics population genomics trusted regulatory spaces trusted research environments services professional services managed services partners show submenu for partners partners cloud partners technology partners services partners data biobank partners instrument partners uk biobank heading learn more about the uk biobank research analysis platform resources show submenu for resources resources learn more with webinars case studies white papers and videos developer resources documentation status upadates learn more with webinars case studies white papers partner briefs and videos blogs company show submenu for company company about dnanexus leadership team careers legal latest latest news our latest news and press coverage read more more dnanexus events contact us sign up log in sign up log in request a demo blog inside dnanexus security update meltdown and spectre vulnerabilities on january 3rd a new class of security flaw was reported that impacts most processors including those that are used by cloud service providers csps such as amazon aws and microsoft azure the issue exploits the speculative execution optimizations in processors as a side channel attack that leak kernel memory meltdown cve 2017 5754 or user memory spectre cve 2017 5715 cve 2017 5753 at this point we have no evidence that this flaw has been exploited at dnanexus patching process and status we are actively working to address this flaw while minimizing any interruption in the dnanexus service we are working with our csps and vendors to receive test and deploy patches efficiently and reliably once available patches are rapidly deployed in our staging environment where automated functional and scalability tests are performed when the patch is verified it is deployed into our production environment without any expected downtime for the dnanexus service on january 3rd the csps have patched their hypervisors to prevent this class of flaw from leaking information between their cloud virtual instances this required a reboot of all dnanexus servers which was completed that same day we have been working with canonical the organization that supports the ubuntu operating system used at dnanexus canonical has released a meltdown patch that we are in the process of testing we will be deploying the patch in two phases to ensure meltdown cannot be exploited by a malicious dnanexus user app we will patch the worker fleet across all regions and clouds followed by deployment of the patch across all supporting systems once the patch has been verified it will be deployed into the worker fleet within 1 hour all new worker instances will take the patch all currently executing jobs will be allowed to complete to minimize disruption then we will initiate the patching process of our supporting systems which is expected to take 1 week to address spectre given the nature of the flaw we expect to receive multiple patches in the future we will work closely with our vendors to ensure the patches are deployed quickly while maintaining our high quality of service profiling the impact on compute performance for standard genomics tools the patches developed to mitigate this security flaw may cause certain applications to run slower this will impact all patched work whether conducted in dnanexus on local machines or in other cloud environments typical guidance from non genomics areas is a slowdown from 5 30 depending on domain the degree of impact depends on the type of computational operations and the only way to reliably determine this is empirically we have performed the exact same analyses on meltdown patched machines with several popular genomic tools to assess the impact our initial analysis indicates that most genomic analyses require around 5 more compute with the meltdown patch with a range of 5 10 we expect this to generalize to the most common types of genomic analysis fortunately this suggests genomic workflows are less impacted than some other reported areas if you have any concerns please contact dnanexus at support dnanexus com facebook twitter linkedin experience dnanexus move beyond genomics learn more share related articles today s precision medicine requires an enterprise strategy news dnanexus offers service for clinical testing labs help save the black rhino most recent clinical diagnostics setting yourself up for success choosing the right omics platform for your diagnostics pipeline meeting where you are at growing with you by darren ames head of solutions science the aligner the bioinformatician s fever dream data nirvana or just a really stable manifest by darren ames head of solutions science building a measurable evidence engine for cell gene and rna therapies by todd oakland svp gm biopharma rx dx dnanexus platform professional services our partners about dnanexus careers resource center developer resources documentation status updates site map legal 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