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Text of the page (random words):
t a hundred years later the fear of goiter never crosses our mind as we daily add a bit of salt and health to our food the truth remains the right dose makes the difference between a poison and a remedy see more at http www cfact org 2014 05 21 fda no low dose chemical dangers sthash dj5cdkow dpuf posted by alan caruba at 3 22 pm no comments email this blogthis share to x share to facebook share to pinterest wednesday february 20 2013 february 15 2013 the wall street journal no ill effect found in human bpa exposure robert lee hotz boston human exposure to a controversial ingredient in many plastic bottles and food containers is too low to be worrisome according to a closer look at 150 studies of an additive called bisphenol a widely known as bpa a toxicologist at the federal pacific northwest national laboratory reported friday that he had re examined studies covering blood levels of bpa which in high enough doses can mimic the sex hormone estrogen among 30 000 people in 19 countries including women and infants he found the exposure levels generally much too low to affect the human body it is thousands of times lower than the levels you see in animals that do cause effects said justin teeguarden a senior research scientist who conducted the analysis at the department of energy laboratory in richland wash mr teeguarden presented his research which was funded by the environmental protection agency at the annual meeting here of the american association for the advancement of science the findings are the latest in a broad ranging scientific controversy that has continued for a decade or more over the safety of the world s food supply and the possible role that bpa may play in a variety of public health problems among other applications bpa is used in bottles soda cans food containers and many other consumer goods to harden the plastics from which they are made and to prevent the growth of germs last summer the food and drug administration banned its use in baby bottles and infant cups but continued to stand behind its safety in other products the world health organization the european food safety authority and japan s national institute of advanced industrial science and technology have all discounted its risk to human health write to robert lee hotz at sciencejournal wsj com a version of this article appeared february 16 2013 on page a3 in the u s edition of the wall street journal with the headline no ill effect found in human bpa exposure posted by alan caruba at 6 52 am no comments email this blogthis share to x share to facebook share to pinterest tuesday february 19 2013 bpa is back new science proves safety health wellness on 02 18 13 by christine lepisto bpa is not so bad after all at least there is not enough of it in our bodies to be causing obesity diabetes cancer liver disease or heart attacks just a few of the modern diseases that have been correlated with the growing presence of this plastic additive in baby and drinking bottles as well as canned food linings the news stems from a session at last week s conference of the american association for the advancement of science aaas entitled can exposure science quell the furor over environmental endocrine disruption the furor over bpa concerned parents have been inundated by studies finding toxic chemicals in the bodies of pregnant women and in our kids favorite canned soups and pasta bpa belongs to a class of chemicals suspected to act as endocrine disruptors what that means in non scientific terms is that bpa can act like the chemical messengers our body uses naturally if our body gets the wrong message at the wrong time the result can be birth defects neurological problems even diseases that might be passed on to future generations no wonder advocates for childrens health have suggested we look for alternatives to bpa fueling the furor is an overwhelming sense of loss of control these chemicals are in our environment in our food in everyday household items who is in charge of keeping us safe in the face of harmful chemicals can science quell the furor if this science came from an industry funded source it could be ignored pending independent confirmation but work funded entirely by the united states environmental protection agency epa under the science to achieve results star program certainly merits a bit of trust at the aaas conference six topics examined recent exposure science on bpa presenting a review of bpa concentrations in humans representing 30 000 people including women and infants in 19 countries the authors posed the question of whether bpa concentrations in humans are high enough to cause endocrine disruption the answer is stated bluntly they are not which raises the next question can this knowledge affect the public s view of the risks posed by bpa why facts don t quell fear a scientists will keep an open mind and look for studies that can repeat the same conclusion just to make sure we did not overlook some important factor or have a flaw in the design of our study but the information presented in this seminar gives strong support to the idea that we do not need to fear bpa as current levels of exposure but a scientist saying so does not suffice especially not when fear makes better headlines which brings us to a real problem this stuff is complex the exposure science that was discussed amongst members of the american association for the advancement of science has math models and medicine underlying it that make it virtually impossible for the average concerned parent to understand here is an overview in much simpler language the amount of bpa found in a review of many studies was not as high as that found in some studies suggesting that the studies that found high levels of bpa reflect contaminated samples or some other form of distortion the amount of bpa found in urine is not a good indicator of how much bpa the body has in the bloodstream where it might confuse the body leaning to disease this simple statement is in the scientific discussion hidden behind a lot of techno speak about intestines livers and chemical reactions required for the bpa to be harmful in the blood the body still prefers estrogen the endocrine messenger our bodies are designed to understand so it would take a lot more bpa screaming its message before our bodies would start listening so do you feel better about bpa based on the simple version of the facts but other scientists will continue to publish reports about bpa and other endocrine disruptors in which they continue to find mechanisms by which these chemicals could cause harm those studies are not lies these chemicals can have harmful effects when studied under different conditions just not at the levels of actual human exposure according to the facts above the important message for parents we always look for the take away message that gives control back to those of us trying to do our best for our kids in a complicated world which brings us to the most important message that the sum of science on bpa delivers so far a lifestyle rich in bpa does correlate with disease bpa probably cannot be blamed at least at the levels encountered the scientists discussing bpa point to another insidious hazard diet is the main source of bpa so an obvious possibility is that poorer diets are associated with higher intake of bpa poorer diets that means processed foods high in sugars and fats could be the real reason why studies show people with higher bpa levels suffer from obesity diabetes and cardiovascular disease the parent hoping to give their child a better future will be thankful for the can linings that keep food safe to eat when offering their kids their favorite canned meals accepting bpa s role in reducing food borne illnesses because there really is no bpa substitute then they will balance those convenient moments with many more meals of good fresh home cooking but that is not science it s just plain common sense http parentables howstuffworks com health wellness bpa back new science proves safety html posted by alan caruba at 6 24 am no comments email this blogthis share to x share to facebook share to pinterest exposure to bpa may be too low to cause problems tue 02 19 2013 pacific northwest national laboratory a controversial component of plastic bottles and canned food linings that have helped make the world s food supply safer has recently come under attack bisphenol a widely known as bpa it has the potential to mimic the sex hormone estrogen if blood and tissue levels are high enough now an analysis of almost 150 bpa exposure studies shows that in the general population people s exposure may be many times too low for bpa to effectively mimic estrogen in the human body the analysis presented at the american association for the advancement of science s annual meeting by toxicologist justin teeguarden of the department of energy s pacific northwest national laboratory shows that bpa in the blood of the general population is many times lower than blood levels that consistently cause toxicity in animals the result suggests that animal studies might not reflect the human bpa experience appropriately looking at all the studies together reveals a remarkably consistent picture of human exposure to bpa with implications for how the risk of human exposure is interpreted says teeguarden at these exposure levels exposure to bpa can t be compared to giving a baby the massive dose of estrogens found in a birth control pill a comparison made by others in addition to evaluating the likelihood of bpa mimicking estrogen in humans teeguarden also analyzed another set of bpa studies that looked at the chemical s toxicity in animals and cells in the lab these 130 studies are significant as a group because they refer to the exposures as low dose implying they are very relevant to human exposures according to his analysis however the low doses actually span an immense range of concentrations a billion fold in addition only a small fraction of the exposures in these self described low dose studies are in the range of human exposures from 0 8 percent to 7 percent depending on the study the term low dose cannot be understood to mean either relevant to human exposures or in the range of human exposures however this is in fact what it has come to mean to the public as well as many in the media says teeguarden analysis of 150 exposure studies the first analysis covered 30 000 individuals including women and infants in 19 countries human blood concentrations were calculated multiple ways using many kinds of exposure data teeguarden looked to see if bpa concentrations were sufficiently high to be a significant source of estrogen like activity in the blood researchers have long known that bpa can bind to the same proteins that estrogen does called estrogen receptors when estrogen is doing its job in the body however in most cases bpa does so much more weakly than estrogen to trigger biological effects through receptors bpa concentrations have to be high enough in the blood to overcome that weakness systematically testing the estrogenicity or the bioactivity of bpa at the part per trillion concentrations we expect in human blood would seem the most scientific way to substantiate or refute this conclusion says teeguarden teeguarden analyzed the data in these studies using multiple independent approaches applied systematically to the data from thousands of individuals the results showed that human blood levels of bpa are expected to be too far below levels required for significant binding to four of the five key estrogen receptors to cause biological effects teeguarden s analysis also confirmed the findings of many academic and government scientists that biologically active bpa is at such low concentrations in the blood that it is beneath toxicologists current ability to detect it raising questions about the role of sample contamination in studies reporting high levels of bpa analysis of 130 toxicity studies in this analysis teeguarden compiled all the bpa studies that included the term low dose as it referred to human exposure by using such terms as low concentration environmentally relevant or human exposure from the 130 studies found he and his pnnl biologist sesha hanson drury compiled all the doses that were actually used in the studies the results showed that a small fraction of the low doses used in these studies are within the range of human exposures with the vast majority being at least 10 to thousands of times higher than what humans are exposed to daily in addition the range of concentrations spans from upwards of 10 grams per kilogram of weight per day down to 100 picograms per kilogram of weight per day a picogram is one millionth of a gram unfortunately the low dose moniker has been used by some to promote the importance of selected toxicity studies for example in arguments to ban bpa says teeguarden for bpa and all chemicals we need more accurate language to present these findings so the public and scientists in other disciplines can understand how human exposures compare to exposures in laboratory studies reporting toxicity posted by alan caruba at 6 05 am no comments email this blogthis share to x share to facebook share to pinterest wednesday february 13 2013 what the sex lives of california mice can tell you by alan caruba according to cheryl rosenfeld an associate professor of biomedical sciences in the university of missouri s bond life science center loading up a bunch of california mice with a mega dose of bisphenol a bpa showed researchers that what we have observed in those models is that bpa affects male rodents differently from females the february 11 um news release that announced this was titled bisphenol a affects sex specific reproductive behaviors in a monogamous animal species with a sub headline that said animal findings suggest that gender may also influence chemical risks for humans so humans are expected to demand that bpa be banned based on the behavior of bpa besotted california mice but not the deer mice on which previous similar research was conducted as noted in the release the two rodent species have contrasting mating behaviors that s right it depends on the sexual proclivities of the species of the mice involved and one has to make a mighty leap of faith that ms rosenfeld s research applies to humans rosenfeld s earlier work received notice in a january 2 2013 science daily article which pointed out that following a three year study using more than 2 800 mice a university of missouri researcher was not able to replicate a series of previous studies by another research group investigating the controversial chemical bpa a synopsis of the earlier study noted that rosenfeld s group extended the studies to include animal numbers that surpassed the prior studies to verify their findings were not a fluke and to provide sufficient numbers of animals to ensure that significant differences would be detected...